Protein: ENY2
Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog)

Gene: ENY2
Organism: Homo sapiens
Interactions: 189
UniProt ID: Q9NPA8

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1446151

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

5

3

Small-scale

0.922

High

245743

GANP
Germinal-center associated nuclear protein

2

1

High-throughput

0.817

High

1258107

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

2

3

High-throughput

0.789

High

1135643

AT7L3
Ataxin-7-like protein 3

11

4

Small-scale

0.759

High

181660

CETN3
Centrin-3

1

1

High-throughput

0.691

High

184749

ATX7
Ataxin-7

3

2

Small-scale

0.667

High

1287325

TAD2B
Transcriptional adapter 2-beta

3

2

High-throughput

0.656

High

1369163

KAT2A
Histone acetyltransferase KAT2A

3

5

Small-scale

0.656

High

1389692

SGF29
SAGA-associated factor 29

3

1

High-throughput

0.656

High

1446155

TRRAP
Transformation/transcription domain-associated protein

3

1

Small-scale

0.656

High

284886

TADA3
Transcriptional adapter 3

3

0

High-throughput

0.628

High

1337586

SP20H
Transcription factor SPT20 homolog

3

0

High-throughput

0.628

High

1086188

CETN1
Centrin-1

1

1

High-throughput

0.618

High

1040380

DYST
Dystonin

1

1

High-throughput

0.618

High

284986

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

2

1

High-throughput

0.611

High

1438397

TAF9B
Transcription initiation factor TFIID subunit 9B

2

2

High-throughput

0.611

High

319176

ST65G
STAGA complex 65 subunit gamma

2

0

High-throughput

0.585

High

1384791

TADA1
Transcriptional adapter 1

2

0

High-throughput

0.585

High

1446159

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

2

0

High-throughput

0.585

High

283626

SUPT3
Transcription initiation protein SPT3 homolog

2

1

High-throughput

0.584

High

373220

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

1091652

TAF10
Transcription initiation factor TFIID subunit 10

2

1

Small-scale

0.584

High

1369213

KAT2B
Histone acetyltransferase KAT2B

2

5

High-throughput

0.584

High

1392518

A7L3B
Ataxin-7-like protein 3B

2

1

Small-scale

0.583

High

1213439

AT7L2
Ataxin-7-like protein 2

2

2

High-throughput

0.558

High

67146

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

3

High-throughput

0.553

High

794634

RBMX
RNA-binding motif protein, X chromosome

1

3

High-throughput

0.536

High

969462

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.536

High

1062660

DHX9
ATP-dependent RNA helicase A

1

1

High-throughput

0.536

High

1215016

INT11
Integrator complex subunit 11

1

1

High-throughput

0.536

High

359747

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.513

High

447475

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

462657

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.513

High

476834

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.513

High

586900

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

658421

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

673966

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.513

High

809858

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

859082

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

859464

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

860370

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

860617

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

954280

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.513

High

961411

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.513

High

967567

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.513

High

969699

RS15A
Small ribosomal subunit protein uS8

1

0

High-throughput

0.513

High

970119

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

972779

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.513

High

972970

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.513

High

973318

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

973596

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

977378

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.513

High

979267

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.513

High

981976

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

982839

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.513

High

983063

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.513

High

983346

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.513

High

985005

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.513

High

986230

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

992974

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.513

High

1089886

ILF3
Interleukin enhancer-binding factor 3

1

0

High-throughput

0.513

High

1117152

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.513

High

1121887

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.513

High

1148055

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.513

High

1151204

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.513

High

1288799

KTN1
Kinectin

1

0

High-throughput

0.513

High

1347612

NEIL3
Endonuclease 8-like 3

1

0

High-throughput

0.513

High

1363632

H1X
Histone H1.10

1

0

High-throughput

0.513

High

1407891

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.513

High

1446150

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

1446152

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.513

High

81735

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

1

1

High-throughput

0.489

High

295241

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

3

High-throughput

0.489

High

550480

PABP1
Polyadenylate-binding protein 1

1

2

High-throughput

0.489

High

939442

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.489

High

1102107

PABP4
Polyadenylate-binding protein 4

1

2

High-throughput

0.489

High

1405773

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.489

High

1446149

AT7L1
Ataxin-7-like protein 1

1

2

High-throughput

0.489

High

650972

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

3

High-throughput

0.481

High

256994

H2B1K
Histone H2B type 1-K

1

4

High-throughput

0.479

High

260489

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.479

High

343061

HERC2
E3 ubiquitin-protein ligase HERC2

1

1

High-throughput

0.479

High

406679

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

430389

JUN
Transcription factor Jun

1

1

High-throughput

0.479

High

461954

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.479

High

468829

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

607128

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

946886

H2B1D
Histone H2B type 1-D

1

4

High-throughput

0.479

High

959977

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

981114

H2B1C
Histone H2B type 1-C/E/F/G/I

1

4

High-throughput

0.479

High

985902

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.479

High

992535

RS21
Small ribosomal subunit protein eS21

1

1

High-throughput

0.479

High

1068314

AHNK
Neuroblast differentiation-associated protein AHNAK

1

1

High-throughput

0.479

High

1157611

TAF12
Transcription initiation factor TFIID subunit 12

1

2

High-throughput

0.479

High

1159337

TAF9
Transcription initiation factor TFIID subunit 9

1

2

High-throughput

0.479

High

1287835

PABP2
Polyadenylate-binding protein 2

1

2

High-throughput

0.479

High

1372312

H2B1H
Histone H2B type 1-H

1

4

High-throughput

0.479

High

1408055

H2B1L
Histone H2B type 1-L

1

4

High-throughput

0.479

High

116823

I6L957
Heterogeneous nuclear ribonucleoproteins A2/B1

1

4

High-throughput

0.470

High

134877

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

170364

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

905171

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

980373

H4
Histone H4

1

0

High-throughput

0.458

High

1039574

TOP2B
DNA topoisomerase 2-beta

1

0

High-throughput

0.458

High

1280518

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1294960

PALB2
Partner and localizer of BRCA2

1

0

Small-scale

0.458

High

1346941

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1446148

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

636033

PRPS3
Ribose-phosphate pyrophosphokinase 3

1

1

High-throughput

0.437

High

686453

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.437

High

837857

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.437

High

961850

RL37A
Large ribosomal subunit protein eL43

1

1

High-throughput

0.437

High

984662

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.437

High

1039409

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.437

High

1214955

CCD18
Coiled-coil domain-containing protein 18

1

1

High-throughput

0.437

High

530409

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

765911

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

954744

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.426

High

887245

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

94439

D6RAT0
Small ribosomal subunit protein eS1

1

1

High-throughput

0.407

High

107278

F8VR69
Ribosomal protein L6

1

1

High-throughput

0.407

High

116401

H3BUK8
Large ribosomal subunit protein eL13

1

1

High-throughput

0.407

High

837418

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

1

High-throughput

0.407

High

954622

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.407

High

1202584

R39L5
Putative ribosomal protein eL39-like 5

1

1

High-throughput

0.407

High

1218550

Q5VVC8
Large ribosomal subunit protein uL5

1

1

High-throughput

0.407

High

1242405

Q6P4E4
RPL37A protein

1

1

High-throughput

0.407

High

1357928

Q8WVC2
40S ribosomal protein S21

1

1

High-throughput

0.407

High

1434990

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

2

0

High-throughput

0.316

High

187803

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

High-throughput

0.279

Low

188039

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

0

High-throughput

0.279

Low

278969

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.279

Low

303635

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.279

Low

428234

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.279

Low

428523

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.279

Low

429000

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.279

Low

460641

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.279

Low

611981

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.279

Low

612789

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.279

Low

616000

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.279

Low

693999

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.279

Low

749141

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.279

Low

770308

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.279

Low

785469

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.279

Low

810400

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.279

Low

824376

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.279

Low

832127

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

0

High-throughput

0.279

Low

842552

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.279

Low

859701

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.279

Low

860014

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.279

Low

868602

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.279

Low

880387

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.279

Low

898838

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.279

Low

954006

IF4A1
Eukaryotic initiation factor 4A-I

1

0

High-throughput

0.279

Low

960900

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.279

Low

975962

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.279

Low

978740

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.279

Low

984553

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.279

Low

985347

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.279

Low

985560

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.279

Low

992088

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.279

Low

1013876

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.279

Low

1016243

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.279

Low

1037655

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.279

Low

1057917

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.279

Low

1126545

CAPR1
Caprin-1

1

0

High-throughput

0.279

Low

1334951

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.279

Low

1446147

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.279

Low

1446153

E41L3
Band 4.1-like protein 3

1

0

High-throughput

0.279

Low

1446154

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.279

Low

1446156

PRC2C
Protein PRRC2C

1

0

High-throughput

0.279

Low

1446157

YTHD2
YTH domain-containing family protein 2

1

0

High-throughput

0.279

Low

1446158

PCDBF
Protocadherin beta-15

1

0

High-throughput

0.279

Low

1323390

LYG1
Lysozyme g-like protein 1

1

0

High-throughput

0.269

Low

423239

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

320070

UFL1
E3 UFM1-protein ligase 1

1

0

Small-scale

0.251

Low

635556

NEBU
Nebulin

1

0

High-throughput

0.249

Low

971125

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

972027

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.249

Low

986742

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.249

Low

995830

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

1132339

GOGB1
Golgin subfamily B member 1

1

0

High-throughput

0.249

Low

1178395

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1256926

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

1290746

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1337381

FXL13
F-box and leucine-rich repeat protein 13

1

0

Small-scale

0.249

Low

1397455

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

255224

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

1034531

TAGL
Transgelin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025