Interactor 1: PTN2 (P17706)
Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP)
Gene: PTPN2
Interactor 2: STAT6 (P42226)
Signal transducer and activator of transcription 6 (IL-4 Stat)
Gene: STAT6
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.55 | 1.00 | 0.747 |
The method score is based on:
Property | Details |
---|---|
Experiments | 17210636 |
Identification Methods | affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation |
Interaction Type | physical association, direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | SH2~Y_phosphatase |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024