Protein: PERI
Peripherin (Neurofilament 4)

Gene: PERI, PRPH
Organism: Homo sapiens
Interactions: 236
UniProt ID: P41219

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005200 - structural constituent of cytoskeleton
GO:0005737 - cytoplasm
GO:0005882 - intermediate filament
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475537

K1C19
Keratin, type I cytoskeletal 19

5

20

High-throughput

0.918

High

606086

DESM
Desmin

4

20

High-throughput

0.898

High

474530

VIME
Vimentin

4

20

High-throughput

0.891

High

777379

K1C20
Keratin, type I cytoskeletal 20

3

20

High-throughput

0.852

High

437114

K2C8
Keratin, type II cytoskeletal 8

3

20

High-throughput

0.847

High

341747

K2C75
Keratin, type II cytoskeletal 75

3

20

High-throughput

0.843

High

385062

K1C14
Keratin, type I cytoskeletal 14

3

20

High-throughput

0.843

High

476277

K1C16
Keratin, type I cytoskeletal 16

3

20

High-throughput

0.843

High

833366

SYNCI
Syncoilin

2

20

High-throughput

0.811

High

618006

K1C15
Keratin, type I cytoskeletal 15

2

20

High-throughput

0.793

High

833275

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.783

High

833281

K1C24
Keratin, type I cytoskeletal 24

2

20

High-throughput

0.783

High

833304

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

436818

K1C18
Keratin, type I cytoskeletal 18

2

20

High-throughput

0.754

High

833238

NEST
Nestin

2

20

High-throughput

0.754

High

833319

LNX1
E3 ubiquitin-protein ligase LNX

4

12

Small-scale

0.689

High

833266

KT33B
Keratin, type I cuticular Ha3-II

1

20

High-throughput

0.665

High

833341

ASPP1
Apoptosis-stimulating of p53 protein 1

3

14

High-throughput

0.653

High

833394

ST38L
Serine/threonine-protein kinase 38-like

2

19

High-throughput

0.628

High

176333

SYNEM
Synemin

1

20

High-throughput

0.618

High

385245

K2C6A
Keratin, type II cytoskeletal 6A

1

20

High-throughput

0.618

High

407258

K2C6B
Keratin, type II cytoskeletal 6B

1

20

High-throughput

0.618

High

407406

K2C1
Keratin, type II cytoskeletal 1

1

20

High-throughput

0.618

High

551541

K2C3
Keratin, type II cytoskeletal 3

1

20

High-throughput

0.618

High

566110

K1C10
Keratin, type I cytoskeletal 10

1

20

High-throughput

0.618

High

566339

K2C5
Keratin, type II cytoskeletal 5

1

20

High-throughput

0.618

High

570369

GFAP
Glial fibrillary acidic protein

1

19

High-throughput

0.618

High

777418

K22E
Keratin, type II cytoskeletal 2 epidermal

1

20

High-throughput

0.618

High

833237

K2C6C
Keratin, type II cytoskeletal 6C

1

20

High-throughput

0.618

High

833251

K22O
Keratin, type II cytoskeletal 2 oral

1

20

High-throughput

0.618

High

833254

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.618

High

833269

K2C72
Keratin, type II cytoskeletal 72

1

20

High-throughput

0.618

High

833277

AINX
Alpha-internexin

1

20

High-throughput

0.618

High

833283

K2C71
Keratin, type II cytoskeletal 71

1

20

High-throughput

0.618

High

833292

IFFO2
Intermediate filament family orphan 2

1

20

High-throughput

0.618

High

833305

K2C1B
Keratin, type II cytoskeletal 1b

1

20

High-throughput

0.618

High

833347

K1C12
Keratin, type I cytoskeletal 12

1

20

High-throughput

0.618

High

833374

KRT84
Keratin, type II cuticular Hb4

1

20

High-throughput

0.618

High

833342

F167A
Protein FAM167A

3

1

High-throughput

0.613

High

680805

PSA1
Proteasome subunit alpha type-1

2

1

High-throughput

0.606

High

684109

DDX6
Probable ATP-dependent RNA helicase DDX6

2

10

High-throughput

0.606

High

833244

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

7

High-throughput

0.606

High

833257

INCA1
Protein INCA1

2

3

High-throughput

0.606

High

833279

CDC37
Hsp90 co-chaperone Cdc37

2

2

High-throughput

0.606

High

833294

PPR18
Phostensin

2

17

High-throughput

0.606

High

833323

CT55
Cancer/testis antigen 55

2

3

High-throughput

0.606

High

833354

KIFC3
Kinesin-like protein KIFC3

2

13

High-throughput

0.606

High

833371

ZC4H2
Zinc finger C4H2 domain-containing protein

2

1

High-throughput

0.606

High

833381

NXF1
Nuclear RNA export factor 1

2

2

High-throughput

0.606

High

833322

TCP1L
T-complex protein 10A homolog 1

3

2

High-throughput

0.603

High

833290

SKT
Sickle tail protein homolog

2

5

High-throughput

0.601

High

833272

KIF14
Kinesin-like protein KIF14

2

20

High-throughput

0.584

High

297769

PIAS2
E3 SUMO-protein ligase PIAS2

2

7

High-throughput

0.553

High

337209

LCA5L
Lebercilin-like protein

2

2

High-throughput

0.553

High

833276

TCEA2
Transcription elongation factor A protein 2

2

3

High-throughput

0.553

High

833293

TTC23
Tetratricopeptide repeat protein 23

2

7

High-throughput

0.553

High

833303

ZN572
Zinc finger protein 572

2

8

High-throughput

0.553

High

833334

MGN2
Protein mago nashi homolog 2

2

3

High-throughput

0.553

High

833335

LENG1
Leukocyte receptor cluster member 1

2

3

High-throughput

0.553

High

361156

SODC
Superoxide dismutase [Cu-Zn]

1

3

High-throughput

0.536

High

640793

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

2

High-throughput

0.536

High

787914

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

5

High-throughput

0.536

High

833250

ANK2
Ankyrin-2

1

15

High-throughput

0.536

High

833261

CUL3
Cullin-3

1

20

High-throughput

0.536

High

833345

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

2

High-throughput

0.536

High

833349

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.536

High

833376

SMOX
Spermine oxidase

1

6

High-throughput

0.515

High

188447

NVL
Nuclear valosin-containing protein-like

1

9

High-throughput

0.515

High

384376

CRYAA
Alpha-crystallin A chain

1

9

High-throughput

0.515

High

833259

NDF1
Neurogenic differentiation factor 1

1

4

High-throughput

0.515

High

833270

FL2D
Pre-mRNA-splicing regulator WTAP

1

6

High-throughput

0.515

High

833284

USH1G
pre-mRNA splicing regulator USH1G

1

11

High-throughput

0.515

High

833297

KLC3
Kinesin light chain 3

1

8

High-throughput

0.515

High

833311

IFT20
Intraflagellar transport protein 20 homolog

1

1

High-throughput

0.515

High

833313

KCD17
BTB/POZ domain-containing protein KCTD17

1

19

High-throughput

0.515

High

833324

BRK1
Protein BRICK1

1

1

High-throughput

0.515

High

833325

PIHD2
PIH1 domain-containing protein 2

1

4

High-throughput

0.515

High

833326

ATLA1
Atlastin-1

1

1

High-throughput

0.515

High

833346

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

12

High-throughput

0.515

High

833350

HAUS7
HAUS augmin-like complex subunit 7

1

1

High-throughput

0.515

High

833382

GCP4
Gamma-tubulin complex component 4

1

6

High-throughput

0.515

High

833386

RN112
RING finger protein 112

1

10

High-throughput

0.515

High

833264

C1D
Nuclear nucleic acid-binding protein C1D

1

0

High-throughput

0.513

High

833307

Q86TN1
ARNT2 protein

1

0

High-throughput

0.493

High

833332

TMM54
Transmembrane protein 54

1

0

High-throughput

0.493

High

833339

RUSF1
RUS family member 1

1

0

High-throughput

0.493

High

833390

CSN3
COP9 signalosome complex subunit 3

1

0

High-throughput

0.493

High

470897

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

8

High-throughput

0.489

High

723993

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.489

High

833302

COX15
Heme A synthase COX15

1

2

High-throughput

0.489

High

155650

FCHO1
F-BAR domain only protein 1

1

1

High-throughput

0.481

High

67759

TBKB1
TANK-binding kinase 1-binding protein 1

1

8

High-throughput

0.479

High

128169

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

High-throughput

0.479

High

140162

SDCB1
Syntenin-1

1

9

High-throughput

0.479

High

157047

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.479

High

159165

ABLM1
Actin-binding LIM protein 1

1

8

High-throughput

0.479

High

169470

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

13

High-throughput

0.479

High

214399

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

2

High-throughput

0.479

High

215906

SYNJ1
Synaptojanin-1

1

5

High-throughput

0.479

High

222788

PRC1
Protein regulator of cytokinesis 1

1

12

High-throughput

0.479

High

244545

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

12

High-throughput

0.479

High

245885

KIF1B
Kinesin-like protein KIF1B

1

10

High-throughput

0.479

High

258792

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.479

High

270782

ROCK2
Rho-associated protein kinase 2

1

16

High-throughput

0.479

High

317242

AL1A2
Retinal dehydrogenase 2

1

1

High-throughput

0.479

High

324618

HEXI1
Protein HEXIM1

1

17

High-throughput

0.479

High

330729

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

347562

BAG3
BAG family molecular chaperone regulator 3

1

6

High-throughput

0.479

High

371376

MYC
Myc proto-oncogene protein

1

15

High-throughput

0.479

High

443244

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.479

High

445765

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

450944

LDHB
L-lactate dehydrogenase B chain

1

1

High-throughput

0.479

High

529266

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.479

High

587583

DESP
Desmoplakin

1

20

High-throughput

0.479

High

664663

CCND1
G1/S-specific cyclin-D1

1

4

High-throughput

0.479

High

778621

PRS7
26S proteasome regulatory subunit 7

1

2

High-throughput

0.479

High

791148

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

833235

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

833236

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

833241

IRAK1
Interleukin-1 receptor-associated kinase 1

1

2

High-throughput

0.479

High

833243

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.479

High

833252

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

10

High-throughput

0.479

High

833253

KIF23
Kinesin-like protein KIF23

1

14

High-throughput

0.479

High

833256

IFFO1
Non-homologous end joining factor IFFO1

1

20

High-throughput

0.479

High

833262

CUL4B
Cullin-4B

1

20

High-throughput

0.479

High

833263

ASPP2
Apoptosis-stimulating of p53 protein 2

1

14

High-throughput

0.479

High

833267

LASP1
LIM and SH3 domain protein 1

1

15

High-throughput

0.479

High

833271

IF4H
Eukaryotic translation initiation factor 4H

1

6

High-throughput

0.479

High

833273

PLEC
Plectin

1

20

High-throughput

0.479

High

833274

STK38
Serine/threonine-protein kinase 38

1

17

High-throughput

0.479

High

833280

KIF7
Kinesin-like protein KIF7

1

5

High-throughput

0.479

High

833282

AAK1
AP2-associated protein kinase 1

1

11

High-throughput

0.479

High

833287

SH319
SH3 domain-containing protein 19

1

20

High-throughput

0.479

High

833288

FA83B
Protein FAM83B

1

12

High-throughput

0.479

High

833291

RHG21
Rho GTPase-activating protein 21

1

10

High-throughput

0.479

High

833299

VP13C
Intermembrane lipid transfer protein VPS13C

1

4

High-throughput

0.479

High

833310

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

7

High-throughput

0.479

High

833314

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

5

High-throughput

0.479

High

833317

IPMK
Inositol polyphosphate multikinase

1

1

High-throughput

0.479

High

833321

BICD2
Protein bicaudal D homolog 2

1

20

High-throughput

0.479

High

833327

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

833330

LPP
Lipoma-preferred partner

1

9

High-throughput

0.479

High

833331

FBXW7
F-box/WD repeat-containing protein 7

1

10

Small-scale

0.479

High

833333

EXOC4
Exocyst complex component 4

1

4

High-throughput

0.479

High

833337

BICD1
Protein bicaudal D homolog 1

1

20

High-throughput

0.479

High

833348

MPP9
M-phase phosphoprotein 9

1

1

High-throughput

0.479

High

833351

ANM1
Protein arginine N-methyltransferase 1

1

9

High-throughput

0.479

High

833353

TCHP
Trichoplein keratin filament-binding protein

1

20

High-throughput

0.479

High

833356

SRBS1
Sorbin and SH3 domain-containing protein 1

1

19

High-throughput

0.479

High

833358

CEP41
Centrosomal protein of 41 kDa

1

1

High-throughput

0.479

High

833362

GAN
Gigaxonin

1

15

High-throughput

0.479

High

833364

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

833367

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

833369

BRD7
Bromodomain-containing protein 7

1

5

High-throughput

0.479

High

833377

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

6

High-throughput

0.479

High

833378

SACS
Sacsin

1

1

High-throughput

0.479

High

833379

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

13

High-throughput

0.479

High

833383

LIMD1
LIM domain-containing protein 1

1

14

High-throughput

0.479

High

833384

TBK1
Serine/threonine-protein kinase TBK1

1

8

High-throughput

0.479

High

833387

DD19B
ATP-dependent RNA helicase DDX19B

1

9

High-throughput

0.479

High

833388

CHIP
E3 ubiquitin-protein ligase CHIP

1

5

High-throughput

0.479

High

833389

SNX6
Sorting nexin-6

1

2

High-throughput

0.479

High

833392

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

1

High-throughput

0.479

High

833395

RTCB
RNA-splicing ligase RtcB homolog

1

1

High-throughput

0.479

High

833396

ARI1
E3 ubiquitin-protein ligase ARIH1

1

18

High-throughput

0.479

High

2796

A0A0C3SFZ9
FCH and mu domain containing endocytic adaptor 1

1

1

High-throughput

0.470

High

165153

PHX2A
Paired mesoderm homeobox protein 2A

1

3

High-throughput

0.470

High

297494

PIAS1
E3 SUMO-protein ligase PIAS1

1

7

High-throughput

0.470

High

833246

RBM11
Splicing regulator RBM11

1

2

High-throughput

0.470

High

833260

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.470

High

833285

ZC21C
Zinc finger C2HC domain-containing protein 1C

1

2

High-throughput

0.470

High

833298

K0408
Uncharacterized protein KIAA0408

1

3

High-throughput

0.470

High

833309

LUR1L
Leucine rich adaptor protein 1-like

1

1

High-throughput

0.470

High

833312

ZN444
Zinc finger protein 444

1

13

High-throughput

0.470

High

833315

SAMD3
Sterile alpha motif domain-containing protein 3

1

1

High-throughput

0.470

High

833338

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

2

High-throughput

0.470

High

833340

CC120
Coiled-coil domain-containing protein 120

1

5

High-throughput

0.470

High

833368

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

6

High-throughput

0.470

High

833391

ZN232
Zinc finger protein 232

1

11

High-throughput

0.470

High

467882

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

0

High-throughput

0.458

High

553142

KCRB
Creatine kinase B-type

1

0

High-throughput

0.458

High

833239

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.458

High

833248

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.458

High

833352

PDD2L
Programmed cell death protein 2-like

1

0

High-throughput

0.458

High

833373

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.458

High

833393

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.458

High

626111

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

15

High-throughput

0.445

High

833245

TERA
Transitional endoplasmic reticulum ATPase

1

9

High-throughput

0.445

High

833247

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

833361

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

66585

CC85C
Coiled-coil domain-containing protein 85C

1

3

High-throughput

0.437

High

67630

RHG32
Rho GTPase-activating protein 32

1

10

High-throughput

0.437

High

71710

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

1

High-throughput

0.437

High

345161

ZMYM6
Zinc finger MYM-type protein 6

1

4

High-throughput

0.437

High

405866

MYCN
N-myc proto-oncogene protein

1

15

High-throughput

0.437

High

833240

MECP2
Methyl-CpG-binding protein 2

1

11

High-throughput

0.437

High

833242

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

15

High-throughput

0.437

High

833249

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

7

High-throughput

0.437

High

833255

GOGA2
Golgin subfamily A member 2

1

20

High-throughput

0.437

High

833258

TFCP2
Alpha-globin transcription factor CP2

1

7

High-throughput

0.437

High

833265

RBM39
RNA-binding protein 39

1

5

High-throughput

0.437

High

833286

PDLI3
PDZ and LIM domain protein 3

1

15

High-throughput

0.437

High

833289

CF132
Uncharacterized protein C6orf132

1

15

High-throughput

0.437

High

833296

SCYL2
SCY1-like protein 2

1

2

High-throughput

0.437

High

833300

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

1

High-throughput

0.437

High

833316

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

7

High-throughput

0.437

High

833318

RASF8
Ras association domain-containing protein 8

1

2

High-throughput

0.437

High

833329

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.437

High

833343

IFT74
Intraflagellar transport protein 74 homolog

1

20

High-throughput

0.437

High

833357

K1671
Uncharacterized protein KIAA1671

1

3

High-throughput

0.437

High

833359

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.437

High

833363

CA198
Uncharacterized protein C1orf198

1

2

High-throughput

0.437

High

833370

ANLN
Anillin

1

12

High-throughput

0.437

High

833372

PDLI7
PDZ and LIM domain protein 7

1

15

High-throughput

0.437

High

833375

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

2

High-throughput

0.437

High

833385

PKHG1
Pleckstrin homology domain-containing family G member 1

1

13

High-throughput

0.437

High

833278

CRY1
Cryptochrome-1

1

0

Small-scale

0.426

High

429454

JUN
Transcription factor Jun

1

13

High-throughput

0.407

High

765207

BMI1
Polycomb complex protein BMI-1

1

14

High-throughput

0.407

High

833328

ESR2
Estrogen receptor beta

1

18

High-throughput

0.407

High

833344

ZMAT2
Zinc finger matrin-type protein 2

2

0

High-throughput

0.316

High

833301

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

0

High-throughput

0.279

Low

833306

CENPV
Centromere protein V

1

0

High-throughput

0.268

Low

833308

TEN1L
CST complex subunit TEN1

1

0

High-throughput

0.268

Low

833320

ENKUR
Enkurin

1

0

High-throughput

0.268

Low

833336

RN183
E3 ubiquitin-protein ligase RNF183

1

0

High-throughput

0.268

Low

270000

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.249

Low

469269

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

0

High-throughput

0.249

Low

568375

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

753906

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

0

High-throughput

0.249

Low

833268

Q149M6
Exophilin 5

1

0

High-throughput

0.249

Low

833295

FAP20
Fanconi anemia core complex-associated protein 20

1

0

High-throughput

0.249

Low

833355

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

833360

CSTFT
Cleavage stimulation factor subunit 2 tau variant

1

0

High-throughput

0.249

Low

833365

CS044
Uncharacterized protein C19orf44

1

0

High-throughput

0.249

Low

833380

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025