HitPredict

Interactor 1: MED12 (A2AGH6)
Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein)
Gene: MED12

Interactor 2: CDK8 (Q8R3L8)
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8)
Gene: CDK8

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.594

The method score is based on:

Property Details
Experiments 25344755, 20720539
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
GO:0016567 - protein ubiquitination
GO:0061630 - ubiquitin protein ligase activity
and 1 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2190
Mm

1 464
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024