Interactor 1: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Interactor 2: DDX17 (Q92841)
Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72)
Gene: DDX17

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35235311, 34349018, 36652389, 19995069, 22365833, 35271311, 37071682, 24581491
Identification Methods affinity chromatography technology, cross-linking study, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, Helicase_C~Helicase_C
Common GO terms GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001837 - epithelial to mesenchymal transition
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
and 17 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 614
Hs

1 729
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024