Interactor 1: HCLS1 (P14317)
Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75)
Gene: HCLS1
Interactor 2: EGLN (P17813)
Endoglin (CD antigen CD105)
Gene: ENG
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.60 | 0.536 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31540324 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005886 - plasma membrane GO:0006355 - regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
