HitPredict

Interactor 1: CHD7 (A2AJK6)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Interactor 2: SMCE1 (O54941)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57)
Gene: Smarce1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21532573
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2986 Mm			1 411
+	Hs
		1281258 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SMCE1_HUMAN (1-411): 3.03e-77: 246: 97.32
+	Hs
		1332326 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX17_HUMAN (2-151): 6.27e-35: 135: 17.88
+	Hs
		818550 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX2_HUMAN (31-149): 1.96e-29: 118: 19.33
+	Hs
		1199209 CHD7_HUMAN (1-2986): 0: 2602: 94.33		PB1_HUMAN (51-138): 9.72e-13: 72.4: 20.46
+	Hs
		818102 CHD9_HUMAN (1-2969): 0: 2063: 45.16		SOX2_HUMAN (31-149): 1.96e-29: 118: 19.33
+	Hs
		1059778 CHD4_HUMAN (681-1972): 0: 886: 27.17		SMCE1_HUMAN (1-411): 3.03e-77: 246: 97.32
+	Mm
		222673 SMCA4_MOUSE (222-1594): 0: 886: 23.03		SMCE1_MOUSE (1-411): 2.56e-76: 244: 100.00
+	Hs
		229300 SMCA5_HUMAN (806-1870): 0: 897: 26.80		UBF1_HUMAN (55-387): 2.03e-44: 166: 15.22
+	Hs
		567697 CHD4_HUMAN (681-1972): 0: 886: 27.17		UBF1_HUMAN (55-387): 2.03e-44: 166: 15.22
+	Hs
		229364 SMCA5_HUMAN (806-1870): 0: 897: 26.80		TFAM_HUMAN (66-259): 7.28e-31: 120: 19.39
+	Hs
		229339 SMCA5_HUMAN (806-1870): 0: 897: 26.80		SOX2_HUMAN (31-149): 1.96e-29: 118: 19.33
+	Hs
		229376 SMCA5_HUMAN (806-1870): 0: 897: 26.80		SSRP1_HUMAN (26-134): 3.96e-26: 112: 18.35
+	Hs
		818056 CHD4_HUMAN (681-1972): 0: 886: 27.17		SOX2_HUMAN (31-149): 1.96e-29: 118: 19.33
+	Hs
		817810 SMCA4_HUMAN (222-1594): 0: 880: 22.38		SOX2_HUMAN (31-149): 1.96e-29: 118: 19.33
+	Hs
		996673 CHD4_HUMAN (681-1972): 0: 886: 27.17		SSRP1_HUMAN (26-134): 3.96e-26: 112: 18.35
+	Hs
		658657 SMCA1_HUMAN (799-1853): 0: 881: 25.90		SSRP1_HUMAN (26-134): 3.96e-26: 112: 18.35
+	Zm
		9144 A0A1D6FIP6_MAIZE (852-1888): 0: 886: 27.64		A0A1D6EUM9_MAIZE (39-181): 4.16e-27: 107: 25.00
+	Hs
		846944 SMCA4_HUMAN (222-1594): 0: 880: 22.38		SSRP1_HUMAN (26-134): 3.96e-26: 112: 18.35
+	Mm
		101533 SMCA4_MOUSE (222-1594): 0: 886: 23.03		F8VQD1_MOUSE (51-138): 8.76e-13: 72.4: 20.46
+	Hs
		1059704 CHD4_HUMAN (681-1972): 0: 886: 27.17		PB1_HUMAN (51-138): 9.72e-13: 72.4: 20.46