HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	18715871, 16085932, 33961781, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 307
+	Hs
		573203 TCPA_HUMAN (1-556): 0: 630: 100.00		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		573211 TCPA_HUMAN (1-556): 0: 630: 100.00		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Hs
		826591 TCPG_HUMAN (5-550): 0: 593: 33.03		PP4C_HUMAN (1-307): 0: 536: 100.00
+	Hs
		826603 TCPG_HUMAN (5-550): 0: 593: 33.03		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		826610 TCPG_HUMAN (5-550): 0: 593: 33.03		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Hs
		890997 TCPH_HUMAN (1-545): 0: 566: 34.84		PP4C_HUMAN (1-307): 0: 536: 100.00
+	Hs
		915267 TCPH_HUMAN (1-545): 0: 566: 34.84		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		930969 TCPH_HUMAN (1-545): 0: 566: 34.84		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Hs
		821143 TCPE_HUMAN (4-530): 0: 550: 31.96		PP4C_HUMAN (1-307): 0: 536: 100.00
+	Hs
		821154 TCPE_HUMAN (4-530): 0: 550: 31.96		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		821161 TCPE_HUMAN (4-530): 0: 550: 31.96		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Hs
		135360 TCPA_HUMAN (1-556): 0: 630: 100.00		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92
+	Hs
		135401 TCPG_HUMAN (5-550): 0: 593: 33.03		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92
+	Hs
		135491 TCPH_HUMAN (1-545): 0: 566: 34.84		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92
+	Sc
		519896 TCPA_YEAST (4-542): 0: 558: 62.57		PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98
+	Sc
		519909 TCPA_YEAST (4-542): 0: 558: 62.57		PP4C_YEAST (6-307): 7.03e-149: 421: 63.07
+	Sc
		618772 TCPG_YEAST (1-538): 0: 552: 29.20		PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98
+	Sc
		688117 TCPG_YEAST (1-538): 0: 552: 29.20		PP4C_YEAST (6-307): 7.03e-149: 421: 63.07
+	Hs
		135397 TCPE_HUMAN (4-530): 0: 550: 31.96		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92
+	Sc
		618781 TCPH_YEAST (10-531): 1.74e-87: 282: 35.10		PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98