Protein: HSF2
Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2)

Gene: HSF2
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q03933

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001162 - RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

961060

HSF1
Heat shock factor protein 1

8

17

Small-scale

0.979

High

977937

HSF4
Heat shock factor protein 4

2

17

High-throughput

0.811

High

903151

WDR5
WD repeat-containing protein 5

5

3

Small-scale

0.717

High

977890

MTUS2
Microtubule-associated tumor suppressor candidate 2

4

2

High-throughput

0.698

High

740135

NUP62
Nuclear pore glycoprotein p62

3

7

Small-scale

0.673

High

314030

BAG4
BAG family molecular chaperone regulator 4

3

6

High-throughput

0.667

High

252989

HSF2B
Heat shock factor 2-binding protein

3

1

High-throughput

0.665

High

418942

TPM3
Tropomyosin alpha-3 chain

5

4

High-throughput

0.662

High

503937

HSP7C
Heat shock cognate 71 kDa protein

2

10

High-throughput

0.628

High

871535

HSP72
Heat shock-related 70 kDa protein 2

2

12

High-throughput

0.611

High

977907

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

2

2

High-throughput

0.611

High

930158

UBC9
SUMO-conjugating enzyme UBC9

2

2

Small-scale

0.594

High

153010

IMPA2
Inositol monophosphatase 2

2

0

High-throughput

0.585

High

977883

ASAH1
Acid ceramidase

2

0

High-throughput

0.585

High

977929

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

977941

DEOC
Deoxyribose-phosphate aldolase

2

0

High-throughput

0.580

High

977901

WDR5B
WD repeat-containing protein 5B

2

3

High-throughput

0.574

High

977931

HPBP1
Hsp70-binding protein 1

2

6

High-throughput

0.574

High

977942

WASC3
WASH complex subunit 3

2

1

High-throughput

0.574

High

718392

PCGF2
Polycomb group RING finger protein 2

1

1

Small-scale

0.573

High

672816

CDC27
Cell division cycle protein 27 homolog

1

4

Small-scale

0.561

High

977882

CDC20
Cell division cycle protein 20 homolog

1

6

Small-scale

0.561

High

977938

FZR1
Fizzy-related protein homolog

1

6

Small-scale

0.561

High

323702

BAG2
BAG family molecular chaperone regulator 2

2

2

High-throughput

0.558

High

977912

CEP76
Centrosomal protein of 76 kDa

2

1

High-throughput

0.553

High

977884

CUL3
Cullin-3

1

0

Small-scale

0.549

High

977925

TRI54
Tripartite motif-containing protein 54

1

3

High-throughput

0.541

High

234208

PEPL
Periplakin

1

4

High-throughput

0.536

High

376221

ANXA1
Annexin A1

1

3

High-throughput

0.536

High

416612

S10A6
Protein S100-A6

1

5

High-throughput

0.536

High

738748

SPB5
Serpin B5

1

1

High-throughput

0.536

High

912809

TYB4
Thymosin beta-4

1

1

High-throughput

0.536

High

977887

SRSF7
Serine/arginine-rich splicing factor 7

1

2

High-throughput

0.536

High

977897

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

1

High-throughput

0.536

High

977914

EVPL
Envoplakin

1

3

High-throughput

0.536

High

977915

RAD50
DNA repair protein RAD50

1

5

High-throughput

0.536

High

977920

LURA1
Leucine rich adaptor protein 1

1

1

High-throughput

0.536

High

977923

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.536

High

977934

CRNN
Cornulin

1

5

High-throughput

0.536

High

977943

CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

0.536

High

904465

1433G
14-3-3 protein gamma

1

6

High-throughput

0.515

High

977916

KAT5
Histone acetyltransferase KAT5

1

2

High-throughput

0.515

High

306577

SCEL
Sciellin

1

0

High-throughput

0.513

High

428574

INVO
Involucrin

1

0

High-throughput

0.513

High

546838

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.513

High

676736

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

High-throughput

0.513

High

727133

DDIT3
DNA damage-inducible transcript 3 protein

1

0

High-throughput

0.513

High

966522

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.513

High

977880

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.513

High

977885

THOC5
THO complex subunit 5 homolog

1

0

High-throughput

0.513

High

977910

INADL
InaD-like protein

1

0

High-throughput

0.513

High

977913

PRCC
Proline-rich protein PRCC

1

0

High-throughput

0.513

High

714191

HSP74
Heat shock 70 kDa protein 4

1

13

Small-scale

0.501

High

977886

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.493

High

977911

LMO3
LIM domain only protein 3

1

0

High-throughput

0.493

High

267396

ECI2
Enoyl-CoA delta isomerase 2

1

1

High-throughput

0.489

High

701681

DSG3
Desmoglein-3

1

2

High-throughput

0.489

High

977906

LIPB2
Liprin-beta-2

1

1

High-throughput

0.489

High

977932

ZNFX1
NFX1-type zinc finger-containing protein 1

1

2

High-throughput

0.489

High

195828

TET3
Methylcytosine dioxygenase TET3

1

2

High-throughput

0.479

High

295620

RMP
Unconventional prefoldin RPB5 interactor 1

1

1

High-throughput

0.479

High

324353

BAG3
BAG family molecular chaperone regulator 3

1

6

High-throughput

0.479

High

339233

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

2

High-throughput

0.479

High

386573

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

574144

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

1

High-throughput

0.479

High

708610

MCM5
DNA replication licensing factor MCM5

1

3

High-throughput

0.479

High

977881

EP300
Histone acetyltransferase p300

1

6

Small-scale

0.479

High

977888

FX4L6
Forkhead box protein D4-like 6

1

1

High-throughput

0.479

High

977895

Q6FHN3
Nucleoside diphosphate kinase

1

3

High-throughput

0.479

High

977899

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

1

2

High-throughput

0.479

High

977900

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

1

High-throughput

0.479

High

977905

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

977908

NUP43
Nucleoporin Nup43

1

4

High-throughput

0.479

High

977917

Q93000
CHL1 protein

1

1

High-throughput

0.479

High

977919

PIWL1
Piwi-like protein 1

1

2

High-throughput

0.479

High

977922

Q96S08
Some homology with holliday junction DNA helicase RUVB like

1

3

High-throughput

0.479

High

977924

BAG1
BAG family molecular chaperone regulator 1

1

2

High-throughput

0.479

High

977926

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

1

High-throughput

0.479

High

977928

Q9HAV2
Heat shock transcription factor 1

1

5

High-throughput

0.479

High

977935

BAG5
BAG family molecular chaperone regulator 5

1

6

High-throughput

0.479

High

977939

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

High-throughput

0.479

High

977944

RBM7
RNA-binding protein 7

1

4

High-throughput

0.479

High

977893

Q5VU62
TPM3 protein

1

3

High-throughput

0.470

High

974531

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.460

High

886395

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

High-throughput

0.458

High

977889

TFDP3
Transcription factor Dp family member 3

1

0

High-throughput

0.458

High

977891

Q5T7U4
General transcription factor IIIC subunit 5

1

0

High-throughput

0.458

High

977896

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

977902

DAA11
Dynein axonemal assembly factor 11

1

0

High-throughput

0.458

High

977927

PIF1
ATP-dependent DNA helicase PIF1

1

0

High-throughput

0.458

High

977940

DYN3
Dynamin-3

1

0

High-throughput

0.458

High

110681

H3BSK8
RB binding protein 6, ubiquitin ligase

1

1

High-throughput

0.445

High

111289

J3KPD3
RNA binding motif protein 7

1

2

High-throughput

0.445

High

977921

CF418
Cilia- and flagella-associated protein 418

1

0

Small-scale

0.438

High

59976

A4FVC0
eIF2C2 protein

1

2

High-throughput

0.437

High

72287

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

151774

IRS4
Insulin receptor substrate 4

1

1

High-throughput

0.437

High

977909

HUS1B
Checkpoint protein HUS1B

1

1

High-throughput

0.437

High

977918

Q96BE0
Heat shock cognate 71 kDa protein

1

13

High-throughput

0.437

High

977930

WSB2
WD repeat and SOCS box-containing protein 2

1

6

High-throughput

0.437

High

66387

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

572121

SAP3
Ganglioside GM2 activator

2

0

High-throughput

0.318

High

850464

PLXA3
Plexin-A3

1

0

High-throughput

0.279

Low

977892

OBSCN
Obscurin

1

0

High-throughput

0.279

Low

977898

GBP6
Guanylate-binding protein 6

1

0

High-throughput

0.279

Low

977903

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.279

Low

977933

SPRR3
Small proline-rich protein 3

1

0

High-throughput

0.279

Low

264479

FBX24
F-box only protein 24

1

0

High-throughput

0.249

Low

677568

CALCR
Calcitonin receptor

1

0

High-throughput

0.249

Low

977894

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

977904

Q8IWP3
Kappa-type opioid receptor

1

0

High-throughput

0.249

Low

977936

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024