Protein: KPYM
Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (p58)

Gene: KPYM, PKM
Organism: Homo sapiens
Interactions: 418
UniProt ID: P14618

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0004713 - protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

572968

KPYM
Pyruvate kinase PKM

3

13

Small-scale

0.834

High

240646

PRKN
E3 ubiquitin-protein ligase parkin

6

5

Small-scale

0.735

High

573010

CTNB1
Catenin beta-1

5

1

Small-scale

0.718

High

573271

HDAC6
Protein deacetylase HDAC6

4

6

Small-scale

0.676

High

371061

MYC
Myc proto-oncogene protein

4

1

High-throughput

0.672

High

573005

KPYR
Pyruvate kinase PKLR

1

14

High-throughput

0.665

High

573281

CHIP
E3 ubiquitin-protein ligase CHIP

3

2

Small-scale

0.664

High

573197

TRI63
E3 ubiquitin-protein ligase TRIM63

3

5

Small-scale

0.656

High

563116

CFTR
Cystic fibrosis transmembrane conductance regulator

3

1

High-throughput

0.650

High

573092

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

3

0

Small-scale

0.650

High

413112

P53
Cellular tumor antigen p53

3

0

Small-scale

0.636

High

573067

MDM2
E3 ubiquitin-protein ligase Mdm2

2

0

Small-scale

0.625

High

573194

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

1

Small-scale

0.624

High

573200

OTUB2
Ubiquitin thioesterase OTUB2

2

1

Small-scale

0.624

High

573042

IMA5
Importin subunit alpha-5

2

0

Small-scale

0.619

High

573234

TRI55
Tripartite motif-containing protein 55

2

8

High-throughput

0.614

High

482229

PAEP
Glycodelin

3

0

High-throughput

0.613

High

573095

CUL3
Cullin-3

2

5

High-throughput

0.611

High

573079

EP300
Histone acetyltransferase p300

2

2

Small-scale

0.601

High

573115

EZH2
Histone-lysine N-methyltransferase EZH2

2

2

High-throughput

0.601

High

573280

UBQL1
Ubiquilin-1

2

2

High-throughput

0.601

High

400223

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

3

Small-scale

0.600

High

573058

GRB2
Growth factor receptor-bound protein 2

3

0

High-throughput

0.597

High

573023

HD
Huntingtin

2

3

High-throughput

0.596

High

461099

HS90A
Heat shock protein HSP 90-alpha

2

5

Small-scale

0.595

High

541308

FGFR1
Fibroblast growth factor receptor 1

2

2

Small-scale

0.595

High

573120

HIF1A
Hypoxia-inducible factor 1-alpha

1

3

Small-scale

0.589

High

573043

DAPK1
Death-associated protein kinase 1

1

2

Small-scale

0.586

High

425289

ISG15
Ubiquitin-like protein ISG15

2

8

High-throughput

0.584

High

445713

ENOA
Alpha-enolase

2

4

High-throughput

0.584

High

573002

PML
Protein PML

2

6

Small-scale

0.584

High

573026

YAP1
Transcriptional coactivator YAP1

2

9

High-throughput

0.584

High

533986

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

1

Small-scale

0.578

High

572999

MK01
Mitogen-activated protein kinase 1

1

4

Small-scale

0.578

High

573253

EGLN3
Prolyl hydroxylase EGLN3

1

1

Small-scale

0.578

High

573097

DX39B
Spliceosome RNA helicase DDX39B

1

2

Small-scale

0.573

High

573046

TERA
Transitional endoplasmic reticulum ATPase

2

3

High-throughput

0.571

High

573289

LOXL2
Lysyl oxidase homolog 2

2

1

Small-scale

0.571

High

573272

DUX4
Double homeobox protein 4

1

2

High-throughput

0.569

High

573284

TRI35
E3 ubiquitin-protein ligase TRIM35

1

3

Small-scale

0.561

High

253230

REV3L
DNA polymerase zeta catalytic subunit

2

0

High-throughput

0.559

High

336336

SVIL
Supervillin

2

0

High-throughput

0.559

High

352918

AGR2
Anterior gradient protein 2 homolog

2

0

Small-scale

0.559

High

446604

NPM
Nucleophosmin

2

0

High-throughput

0.559

High

573232

ACE2
Angiotensin-converting enzyme 2

2

0

High-throughput

0.559

High

573259

ANLN
Anillin

2

0

High-throughput

0.559

High

573129

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

1

High-throughput

0.552

High

568997

ENOB
Beta-enolase

1

4

High-throughput

0.541

High

573030

HXA1
Homeobox protein Hox-A1

1

1

High-throughput

0.541

High

573036

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.541

High

573037

FXR2
RNA-binding protein FXR2

1

1

High-throughput

0.541

High

573072

TF65
Transcription factor p65

1

1

High-throughput

0.541

High

573076

PAX8
Paired box protein Pax-8

1

1

High-throughput

0.541

High

573184

LMO7
LIM domain only protein 7

1

1

High-throughput

0.541

High

573213

RHG07
Rho GTPase-activating protein 7

1

1

High-throughput

0.541

High

573215

ARX
Homeobox protein ARX

1

2

High-throughput

0.541

High

573168

KDM8
Bifunctional peptidase and arginyl-hydroxylase JMJD5

1

0

Small-scale

0.537

High

468024

HS90B
Heat shock protein HSP 90-beta

1

5

Small-scale

0.536

High

528992

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.536

High

572972

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

573006

CLIP1
CAP-Gly domain-containing linker protein 1

1

2

High-throughput

0.536

High

573008

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

573028

ARRB1
Beta-arrestin-1

1

1

High-throughput

0.536

High

573041

NEK4
Serine/threonine-protein kinase Nek4

1

6

High-throughput

0.536

High

573065

CDK16
Cyclin-dependent kinase 16

1

3

High-throughput

0.536

High

573093

CUL1
Cullin-1

1

5

High-throughput

0.536

High

573094

CUL2
Cullin-2

1

5

High-throughput

0.536

High

573124

GRDN
Girdin

1

1

High-throughput

0.536

High

573193

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.536

High

573195

CUL5
Cullin-5

1

5

High-throughput

0.536

High

573270

NLK
Serine/threonine-protein kinase NLK

1

6

High-throughput

0.536

High

573279

DD19B
ATP-dependent RNA helicase DDX19B

1

1

High-throughput

0.536

High

332736

EPM2A
Laforin

1

0

Small-scale

0.529

High

573045

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.529

High

573114

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

7

Small-scale

0.527

High

573212

CLIC6
Chloride intracellular channel protein 6

1

0

High-throughput

0.518

High

573242

EGLN1
Egl nine homolog 1

1

1

Small-scale

0.515

High

572989

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.515

High

573004

MPIP1
M-phase inducer phosphatase 1

1

0

Small-scale

0.513

High

274456

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

336588

PPN
Papilin

1

0

High-throughput

0.513

High

388982

FINC
Fibronectin

1

0

High-throughput

0.513

High

415988

CP1A1
Cytochrome P450 1A1

1

0

High-throughput

0.513

High

571746

FPPS
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.513

High

572975

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

572977

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

573179

MIPT3
TRAF3-interacting protein 1

1

0

Small-scale

0.513

High

573180

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

573183

TRUB1
Pseudouridylate synthase TRUB1

1

0

High-throughput

0.513

High

573228

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

549038

CDK4
Cyclin-dependent kinase 4

1

4

High-throughput

0.508

High

572980

RCC1
Regulator of chromosome condensation

1

1

High-throughput

0.508

High

572984

ANXA7
Annexin A7

1

1

High-throughput

0.508

High

573100

GRB7
Growth factor receptor-bound protein 7

1

2

High-throughput

0.508

High

185402

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

421427

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

572995

1433T
14-3-3 protein theta

1

2

High-throughput

0.501

High

573055

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.501

High

573060

SUMO1
Small ubiquitin-related modifier 1

1

2

Small-scale

0.501

High

573074

UBE3A
Ubiquitin-protein ligase E3A

1

7

Small-scale

0.501

High

573204

AURKB
Aurora kinase B

1

4

Small-scale

0.501

High

573292

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

1

Small-scale

0.501

High

327543

ELP1
Elongator complex protein 1

1

0

Small-scale

0.493

High

573021

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

573106

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

573191

NDRG1
Protein NDRG1

1

0

Small-scale

0.493

High

573150

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

573170

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.493

High

573208

BOD1
Biorientation of chromosomes in cell division protein 1

1

0

High-throughput

0.493

High

405391

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

573019

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

573054

RAP1B
Ras-related protein Rap-1b

1

0

High-throughput

0.486

High

573119

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

573258

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.486

High

573274

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.486

High

354893

CHK2
Serine/threonine-protein kinase Chk2

1

1

Small-scale

0.484

High

407784

SHBG
Sex hormone-binding globulin

1

2

Small-scale

0.481

High

573047

DPOE2
DNA polymerase epsilon subunit 2

1

1

High-throughput

0.481

High

573178

LNX1
E3 ubiquitin-protein ligase LNX

1

2

High-throughput

0.481

High

573224

MYOC
Myocilin

1

1

Small-scale

0.481

High

573257

NXT2
NTF2-related export protein 2

1

2

High-throughput

0.481

High

573051

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.480

High

129978

PGRC1
Membrane-associated progesterone receptor component 1

1

1

Small-scale

0.479

High

131313

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

1

Small-scale

0.479

High

131707

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

5

Small-scale

0.479

High

136816

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

2

High-throughput

0.479

High

137939

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

High-throughput

0.479

High

159493

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

3

High-throughput

0.479

High

172004

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

3

High-throughput

0.479

High

181247

PGRC2
Membrane-associated progesterone receptor component 2

1

1

High-throughput

0.479

High

188162

HDAC3
Histone deacetylase 3

1

3

Small-scale

0.479

High

247223

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

259374

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

271220

CPNE3
Copine-3

1

1

High-throughput

0.479

High

279112

ULK1
Serine/threonine-protein kinase ULK1

1

2

Small-scale

0.479

High

302357

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

High-throughput

0.479

High

323147

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

High-throughput

0.479

High

330627

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.479

High

380253

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

3

Small-scale

0.479

High

405748

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

408647

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

411289

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

479105

ENOG
Gamma-enolase

1

4

Small-scale

0.479

High

484888

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

2

High-throughput

0.479

High

507485

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

Small-scale

0.479

High

519705

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

565119

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

565758

EF2
Elongation factor 2

1

2

High-throughput

0.479

High

568104

DRB4
HLA class II histocompatibility antigen, DR beta 4 chain

1

3

Small-scale

0.479

High

572969

PO2F1
POU domain, class 2, transcription factor 1

1

2

Small-scale

0.479

High

572979

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

572982

RO52
E3 ubiquitin-protein ligase TRIM21

1

3

High-throughput

0.479

High

572986

EFNA1
Ephrin-A1

1

1

High-throughput

0.479

High

572987

ZP3
Zona pellucida sperm-binding protein 3

1

2

Small-scale

0.479

High

572992

CDK2
Cyclin-dependent kinase 2

1

4

High-throughput

0.479

High

572993

PSA3
Proteasome subunit alpha type-3

1

1

Small-scale

0.479

High

572994

U2AF2
Splicing factor U2AF 65 kDa subunit

1

3

High-throughput

0.479

High

573007

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

573009

MCM5
DNA replication licensing factor MCM5

1

6

High-throughput

0.479

High

573014

MSX2
Homeobox protein MSX-2

1

2

High-throughput

0.479

High

573015

FUS
RNA-binding protein FUS

1

1

High-throughput

0.479

High

573016

TRI23
E3 ubiquitin-protein ligase TRIM23

1

1

High-throughput

0.479

High

573017

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.479

High

573018

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

573027

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

573033

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.479

High

573034

GSK3B
Glycogen synthase kinase-3 beta

1

5

High-throughput

0.479

High

573035

CDK9
Cyclin-dependent kinase 9

1

5

High-throughput

0.479

High

573040

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

High-throughput

0.479

High

573048

HDAC4
Histone deacetylase 4

1

6

High-throughput

0.479

High

573049

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

1

High-throughput

0.479

High

573059

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.479

High

573062

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

573063

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

3

Small-scale

0.479

High

573066

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

573068

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

573075

ZP2
Zona pellucida sperm-binding protein 2

1

2

Small-scale

0.479

High

573080

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.479

High

573081

ZP4
Zona pellucida sperm-binding protein 4

1

2

Small-scale

0.479

High

573082

ANK3
Ankyrin-3

1

1

High-throughput

0.479

High

573083

NFX1
Transcriptional repressor NF-X1

1

2

High-throughput

0.479

High

573085

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

Small-scale

0.479

High

573087

MK07
Mitogen-activated protein kinase 7

1

5

Small-scale

0.479

High

573088

TIF1B
Transcription intermediary factor 1-beta

1

7

High-throughput

0.479

High

573090

IKZF1
DNA-binding protein Ikaros

1

1

High-throughput

0.479

High

573096

CUL4A
Cullin-4A

1

5

High-throughput

0.479

High

573098

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

3

High-throughput

0.479

High

573101

RBM39
RNA-binding protein 39

1

1

High-throughput

0.479

High

573104

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.479

High

573105

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

1

High-throughput

0.479

High

573107

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

573108

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

573109

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.479

High

573110

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

573117

CRY1
Cryptochrome-1

1

1

High-throughput

0.479

High

573122

DRB5
HLA class II histocompatibility antigen, DR beta 5 chain

1

3

Small-scale

0.479

High

573125

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

573126

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.479

High

573131

RC3H1
Roquin-1

1

1

Small-scale

0.479

High

573133

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

573134

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

573139

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

573142

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

1

High-throughput

0.479

High

573143

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

573145

ASXL2
Putative Polycomb group protein ASXL2

1

4

High-throughput

0.479

High

573151

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

6

High-throughput

0.479

High

573156

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

Small-scale

0.479

High

573157

HOOK3
Protein Hook homolog 3

1

1

High-throughput

0.479

High

573159

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

573160

ARMC8
Armadillo repeat-containing protein 8

1

2

Small-scale

0.479

High

573162

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

1

High-throughput

0.479

High

573164

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.479

High

573166

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.479

High

573173

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

573176

TRI58
E3 ubiquitin-protein ligase TRIM58

1

3

Small-scale

0.479

High

573177

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.479

High

573186

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

1

High-throughput

0.479

High

573187

SYNE2
Nesprin-2

1

1

High-throughput

0.479

High

573188

DDB2
DNA damage-binding protein 2

1

2

Small-scale

0.479

High

573189

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

573190

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

573192

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

573196

IGSF8
Immunoglobulin superfamily member 8

1

1

High-throughput

0.479

High

573202

TRI44
Tripartite motif-containing protein 44

1

3

Small-scale

0.479

High

573209

PAWR
PRKC apoptosis WT1 regulator protein

1

1

High-throughput

0.479

High

573210

CLMN
Calmin

1

1

High-throughput

0.479

High

573217

RANB9
Ran-binding protein 9

1

2

Small-scale

0.479

High

573218

RUFY1
RUN and FYVE domain-containing protein 1

1

1

High-throughput

0.479

High

573221

KIF2C
Kinesin-like protein KIF2C

1

2

Small-scale

0.479

High

573222

EPAS1
Endothelial PAS domain-containing protein 1

1

3

Small-scale

0.479

High

573226

PELO
Protein pelota homolog

1

1

High-throughput

0.479

High

573229

TRAF4
TNF receptor-associated factor 4

1

4

Small-scale

0.479

High

573230

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.479

High

573231

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

573236

TRI31
E3 ubiquitin-protein ligase TRIM31

1

4

High-throughput

0.479

High

573239

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.479

High

573241

DDX24
ATP-dependent RNA helicase DDX24

1

2

High-throughput

0.479

High

573246

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

6

High-throughput

0.479

High

573252

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

573254

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

573255

RC3H2
Roquin-2

1

1

Small-scale

0.479

High

573256

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

573260

SAR1A
Small COPII coat GTPase SAR1A

1

3

High-throughput

0.479

High

573264

HELLS
Lymphoid-specific helicase

1

2

Small-scale

0.479

High

573266

RAB20
Ras-related protein Rab-20

1

2

High-throughput

0.479

High

573268

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

573273

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

573276

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.479

High

573277

MKLN1
Muskelin

1

1

Small-scale

0.479

High

573278

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

573283

TRI33
E3 ubiquitin-protein ligase TRIM33

1

7

Small-scale

0.479

High

573285

HDAC5
Histone deacetylase 5

1

6

High-throughput

0.479

High

573286

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.479

High

573290

TRAF6
TNF receptor-associated factor 6

1

9

Small-scale

0.479

High

573294

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.479

High

573071

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.460

High

573261

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.460

High

193969

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

257323

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

271866

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

284059

SRS10
Serine/arginine-rich splicing factor 10

1

0

High-throughput

0.458

High

285576

BAF
Barrier-to-autointegration factor

1

0

Small-scale

0.458

High

293146

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

315076

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

319359

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

320374

SASH1
SAM and SH3 domain-containing protein 1

1

0

High-throughput

0.458

High

324489

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

345319

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

347506

BAG3
BAG family molecular chaperone regulator 3

1

0

Small-scale

0.458

High

349774

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

377390

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

377941

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

536416

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

555848

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

572970

ETS1
Protein C-ets-1

1

0

High-throughput

0.458

High

572971

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

572973

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

572974

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

572976

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.458

High

572985

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

572990

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

0

Small-scale

0.458

High

572997

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

572998

PSA5
Proteasome subunit alpha type-5

1

0

Small-scale

0.458

High

573001

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

573003

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.458

High

573012

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

573020

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.458

High

573024

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

573025

NOP2
28S rRNA

1

0

High-throughput

0.458

High

573029

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.458

High

573031

CTCF
Transcriptional repressor CTCF

1

0

Small-scale

0.458

High

573038

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

573044

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

573050

CD81
CD81 antigen

1

0

High-throughput

0.458

High

573053

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

573056

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

573057

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

573064

VIGLN
Vigilin

1

0

High-throughput

0.458

High

573070

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

573073

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.458

High

573078

ADCY2
Adenylate cyclase type 2

1

0

High-throughput

0.458

High

573086

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

573091

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

573099

FA50A
Protein FAM50A

1

0

High-throughput

0.458

High

573102

CUL7
Cullin-7

1

0

High-throughput

0.458

High

573103

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

573111

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

573118

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

573121

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

573135

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

573136

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

573137

CDC73
Parafibromin

1

0

High-throughput

0.458

High

573138

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

573141

ZN574
Zinc finger protein 574

1

0

High-throughput

0.458

High

573144

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

573147

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

573148

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

573149

Z804A
Zinc finger protein 804A

1

0

High-throughput

0.458

High

573152

SLN11
Schlafen family member 11

1

0

Small-scale

0.458

High

573153

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

573154

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

573155

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

573158

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

573167

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

573174

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

573175

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

573181

STAG1
Cohesin subunit SA-1

1

0

High-throughput

0.458

High

573182

TP8L1
Tumor necrosis factor alpha-induced protein 8-like protein 1

1

0

Small-scale

0.458

High

573185

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.458

High

573198

PP14B
Protein phosphatase 1 regulatory subunit 14B

1

0

High-throughput

0.458

High

573199

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

573201

PABP5
Polyadenylate-binding protein 5

1

0

High-throughput

0.458

High

573207

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

573211

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

573214

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.458

High

573216

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

573220

NECD
Necdin

1

0

High-throughput

0.458

High

573223

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

573225

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

573233

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

0

High-throughput

0.458

High

573235

GTPB4
GTP-binding protein 4

1

0

Small-scale

0.458

High

573237

API5
Apoptosis inhibitor 5

1

0

High-throughput

0.458

High

573243

LHPP
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

1

0

Small-scale

0.458

High

573244

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

573245

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.458

High

573248

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

573262

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

573265

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

573269

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

573275

FBXL4
F-box/LRR-repeat protein 4

1

0

Small-scale

0.458

High

573282

FAF1
FAS-associated factor 1

1

0

High-throughput

0.458

High

573288

FBX7
F-box only protein 7

1

0

High-throughput

0.458

High

573291

PPME1
Protein phosphatase methylesterase 1

1

0

Small-scale

0.458

High

350682

NOE2
Noelin-2

1

1

High-throughput

0.457

High

521183

ARAF
Serine/threonine-protein kinase A-Raf

1

3

Small-scale

0.457

High

573251

SAV1
Protein salvador homolog 1

1

7

Small-scale

0.457

High

184570

MK13
Mitogen-activated protein kinase 13

1

6

Small-scale

0.445

High

354520

PAK4
Serine/threonine-protein kinase PAK 4

1

3

High-throughput

0.445

High

429228

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

442865

PRGR
Progesterone receptor

1

2

Small-scale

0.445

High

567248

TCTP
Translationally-controlled tumor protein

1

1

Small-scale

0.445

High

572983

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.445

High

572996

MK03
Mitogen-activated protein kinase 3

1

4

Small-scale

0.445

High

573000

GRN
Progranulin

1

1

High-throughput

0.445

High

573011

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.445

High

573052

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

3

High-throughput

0.445

High

573061

H31
Histone H3.1

1

2

Small-scale

0.445

High

573077

LG3BP
Galectin-3-binding protein

1

1

High-throughput

0.445

High

573084

STK4
Serine/threonine-protein kinase 4

1

2

High-throughput

0.445

High

573089

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

573140

DUX4C
Double homeobox protein 4C

1

2

High-throughput

0.445

High

573203

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.445

High

573240

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

3

High-throughput

0.445

High

573247

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

3

High-throughput

0.445

High

573250

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

3

High-throughput

0.445

High

138445

BIN1
Myc box-dependent-interacting protein 1

1

0

High-throughput

0.438

High

573263

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

573112

UBE3C
Ubiquitin-protein ligase E3C

1

8

Small-scale

0.437

High

573123

ANR55
Ankyrin repeat domain-containing protein 55

1

3

High-throughput

0.437

High

573130

NHSL1
NHS-like protein 1

1

3

High-throughput

0.437

High

573132

OTUD1
OTU domain-containing protein 1

1

1

High-throughput

0.437

High

573146

KCTD9
BTB/POZ domain-containing protein KCTD9

1

2

High-throughput

0.437

High

573205

RN185
E3 ubiquitin-protein ligase RNF185

1

3

Small-scale

0.437

High

573206

DIRA2
GTP-binding protein Di-Ras2

1

1

Small-scale

0.437

High

135474

DNM1L
Dynamin-1-like protein

1

0

Small-scale

0.426

High

572981

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

572991

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

573069

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

573163

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.426

High

573219

ZBT18
Zinc finger and BTB domain-containing protein 18

1

0

High-throughput

0.426

High

573032

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

114545

H0YI16
Pro-apoptotic WT1 regulator

1

1

High-throughput

0.407

High

573113

SYCP1
Synaptonemal complex protein 1

3

0

High-throughput

0.334

High

573227

TINF2
TERF1-interacting nuclear factor 2

1

0

High-throughput

0.299

High

573039

CCR4
C-C chemokine receptor type 4

1

0

High-throughput

0.282

High

573238

SEM4C
Semaphorin-4C

1

0

High-throughput

0.279

Low

572988

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.269

Low

573293

Q9Y649
GW128

1

0

High-throughput

0.268

Low

325423

RPP14
Ribonuclease P protein subunit p14

1

0

High-throughput

0.265

Low

60854

C144A
Coiled-coil domain-containing protein 144A

1

0

High-throughput

0.249

Low

64729

GOG6B
Golgin subfamily A member 6B

1

0

High-throughput

0.249

Low

105249

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

239704

PCDH7
Protocadherin-7

1

0

High-throughput

0.249

Low

572978

INAR1
Interferon alpha/beta receptor 1

1

0

Small-scale

0.249

Low

573013

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

573116

AINX
Alpha-internexin

1

0

High-throughput

0.249

Low

573127

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

573128

FRPD3
FERM and PDZ domain-containing protein 3

1

0

High-throughput

0.249

Low

573165

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.249

Low

573171

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

573172

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

573249

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.249

Low

573267

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

573287

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

573022

S19A1
Reduced folate transporter

1

0

High-throughput

0.232

Low

573161

S41A1
Solute carrier family 41 member 1

1

0

High-throughput

0.232

Low

573169

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025