HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: ERCC8 (Q13216)
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)
Gene: ERCC8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	29531219, 34581821, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 396
+	Hs
		826641 TCPG_HUMAN (5-550): 0: 593: 33.03		ERCC8_HUMAN (1-396): 7.48e-87: 270: 100.00
+	Hs
		573446 TCPA_HUMAN (1-556): 0: 630: 100.00		TBL1Y_HUMAN (2-321): 1.67e-67: 224: 18.24
+	Hs
		573406 TCPA_HUMAN (1-556): 0: 630: 100.00		FBXW7_HUMAN (128-395): 4.9e-60: 208: 13.76
+	Hs
		826848 TCPG_HUMAN (5-550): 0: 593: 33.03		TBL1Y_HUMAN (2-321): 1.67e-67: 224: 18.24
+	Hs
		573412 TCPA_HUMAN (1-556): 0: 630: 100.00		SNR40_HUMAN (140-394): 5.23e-55: 186: 13.41
+	Hs
		826807 TCPG_HUMAN (5-550): 0: 593: 33.03		FBXW7_HUMAN (128-395): 4.9e-60: 208: 13.76
+	Hs
		573201 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		573346 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	Hs
		573384 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1B_HUMAN (228-395): 1.45e-33: 132: 15.29
+	Hs
		826601 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		826748 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	Hs
		792942 TCPG_HUMAN (5-550): 0: 593: 33.03		LIS1_HUMAN (218-395): 1.1e-38: 145: 14.44
+	Hs
		573371 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Hs
		826784 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1B_HUMAN (228-395): 1.45e-33: 132: 15.29
+	Hs
		573279 TCPA_HUMAN (1-556): 0: 630: 100.00		RBBP7_HUMAN (129-368): 4.26e-15: 78.3: 19.22
+	Hs
		826772 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Hs
		573235 TCPA_HUMAN (1-556): 0: 630: 100.00		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		196954 TCPA_HUMAN (1-556): 0: 630: 100.00		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27
+	Hs
		826632 TCPG_HUMAN (5-550): 0: 593: 33.03		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		196973 TCPG_HUMAN (5-550): 0: 593: 33.03		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27