HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 746
+	Hs
		826679 TCPG_HUMAN (5-550): 0: 593: 33.03		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		516942 TCPA_MOUSE (1-556): 0: 622: 96.40		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		1080275 TCPH_HUMAN (1-545): 0: 566: 34.84		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945989 TCPG_MOUSE (5-550): 0: 593: 32.48		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		821226 TCPE_HUMAN (4-530): 0: 550: 31.96		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945919 TCPH_MOUSE (1-551): 0: 577: 35.18		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		573423 TCPA_HUMAN (1-556): 0: 630: 100.00		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		573479 TCPA_HUMAN (1-556): 0: 630: 100.00		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203623 TCPA_HUMAN (1-556): 0: 630: 100.00		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Sc
		519937 TCPA_YEAST (4-542): 0: 558: 62.57		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Sc
		755768 TCPG_YEAST (1-538): 0: 552: 29.20		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Hs
		826825 TCPG_HUMAN (5-550): 0: 593: 33.03		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		826887 TCPG_HUMAN (5-550): 0: 593: 33.03		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203640 TCPG_HUMAN (5-550): 0: 593: 33.03		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		1296406 TCPH_HUMAN (1-545): 0: 566: 34.84		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		1306682 TCPH_HUMAN (1-545): 0: 566: 34.84		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203775 TCPH_HUMAN (1-545): 0: 566: 34.84		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		821409 TCPE_HUMAN (4-530): 0: 550: 31.96		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203639 TCPE_HUMAN (4-530): 0: 550: 31.96		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Sc
		755775 TCPH_YEAST (10-531): 1.74e-87: 282: 35.10		SET1_YEAST (205-733): 1.13e-84: 292: 16.01