HitPredict

Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: EPOR (P19235)
Erythropoietin receptor (EPO-R)
Gene: EPOR

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.528

Property	Details
Experiments	14527337
Identification Methods	pull down, coimmunoprecipitation, phosphatase assay
Interaction Type	physical association, dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 508
+	Hs
		581148 PTPRB_HUMAN (2-311): 4.08e-124: 398: 34.39		EPOR_HUMAN (1-508): 8.71e-145: 427: 100.00
+	Hs
		500943 PTN1_HUMAN (1-435): 0: 539: 100.00		GHR_HUMAN (6-482): 1.38e-87: 283: 15.10
+	Hs
		581162 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		EPOR_HUMAN (1-508): 8.71e-145: 427: 100.00
+	Hs
		500942 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		GHR_HUMAN (6-482): 1.38e-87: 283: 15.10
+	Hs
		573583 PTN1_HUMAN (1-435): 0: 539: 100.00		EPHA8_HUMAN (2-369): 1.81e-38: 152: 13.80
+	Hs
		441174 PTPRC_HUMAN (16-337): 3.28e-77: 263: 22.95		EPOR_HUMAN (1-508): 8.71e-145: 427: 100.00
+	Hs
		500946 PTPRB_HUMAN (2-311): 4.08e-124: 398: 34.39		GHR_HUMAN (6-482): 1.38e-87: 283: 15.10
+	Hs
		500961 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		GHR_HUMAN (6-482): 1.38e-87: 283: 15.10
+	Hs
		500959 PTN12_HUMAN (24-314): 1e-122: 376: 33.55		GHR_HUMAN (6-482): 1.38e-87: 283: 15.10
+	Hs
		616945 PTPRD_HUMAN (1-278): 8.51e-109: 354: 31.45		IL2RG_HUMAN (15-351): 3.88e-59: 201: 17.35
+	Hs
		441167 PTPRC_HUMAN (16-337): 3.28e-77: 263: 22.95		GHR_HUMAN (6-482): 1.38e-87: 283: 15.10
+	Hs
		1031984 PTPRS_HUMAN (1-278): 3.66e-109: 355: 30.74		I13R2_HUMAN (22-284): 2.33e-52: 183: 16.67
+	Hs
		265768 PTPRS_HUMAN (1-278): 3.66e-109: 355: 30.74		CRLF1_HUMAN (14-250): 1.84e-49: 177: 22.18
+	Hs
		489962 PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94		I13R2_HUMAN (22-284): 2.33e-52: 183: 16.67
+	Hs
		817318 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		LEPR_HUMAN (49-259): 5.61e-29: 123: 12.50
+	Hs
		616942 PTPRD_HUMAN (1-278): 8.51e-109: 354: 31.45		IL3RA_HUMAN (37-316): 4.98e-41: 153: 20.00
+	Hs
		616944 PTPRD_HUMAN (1-278): 8.51e-109: 354: 31.45		EPHA8_HUMAN (2-369): 1.81e-38: 152: 13.80
+	Hs
		489957 PTPRS_HUMAN (1-278): 3.66e-109: 355: 30.74		PTPRF_HUMAN (8-269): 5.2e-13: 73.9: 16.31
+	Hs
		489886 PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94		PTPRF_HUMAN (8-269): 5.2e-13: 73.9: 16.31
+	Mm
		56906 PTPRA_MOUSE (12-278): 2.85e-105: 332: 31.99		PTPRF_MOUSE (6-234): 1.46e-11: 69.2: 17.24