HitPredict

Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.535

Property	Details
Experiments	10480872
Identification Methods	enzymatic study, in-gel kinase assay, protein kinase assay
Interaction Type	direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 499
+	Hs
		573612 PTN1_HUMAN (1-435): 0: 539: 100.00		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		414726 PTN1_HUMAN (1-435): 0: 539: 100.00		CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95
+	Hs
		573685 PTN1_HUMAN (1-435): 0: 539: 100.00		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		1031979 PTPRS_HUMAN (1-278): 3.66e-109: 355: 30.74		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		833841 PTN22_HUMAN (297-430): 8.46e-19: 91.2: 13.10		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		414758 PTN6_HUMAN (342-432): 1.75e-12: 71.2: 10.48		CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95