HitPredict

Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 232
+	Hs
		573644 PTN1_HUMAN (1-435): 0: 539: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		573624 PTN1_HUMAN (1-435): 0: 539: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		573655 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		573643 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		573653 PTN1_HUMAN (1-435): 0: 539: 100.00		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		545198 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		573648 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		573659 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		436151 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		120299 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		573919 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Hs
		545197 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		570514 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		570523 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		893944 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		892338 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		545345 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		436150 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		436276 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		120410 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76