Protein: CCNA1
Cyclin-A1

Gene: CCNA1
Organism: Homo sapiens
Interactions: 88
UniProt ID: P78396

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005815 - microtubule organizing center

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

667764

CDK2
Cyclin-dependent kinase 2

21

20

Small-scale

0.986

High

857308

CDN1B
Cyclin-dependent kinase inhibitor 1B

8

15

Small-scale

0.968

High

808019

CDN1A
Cyclin-dependent kinase inhibitor 1

8

15

Small-scale

0.968

High

443299

CDK1
Cyclin-dependent kinase 1

4

20

Small-scale

0.882

High

629098

CCNA2
Cyclin-A2

3

5

High-throughput

0.861

High

1007661

FZR1
Fizzy-related protein homolog

8

20

Small-scale

0.748

High

719007

WEE1
Wee1-like protein kinase

1

9

Small-scale

0.724

High

1007633

SKP2
S-phase kinase-associated protein 2

4

4

Small-scale

0.696

High

1007655

CDT1
DNA replication factor Cdt1

4

2

Small-scale

0.672

High

1007630

CDC20
Cell division cycle protein 20 homolog

3

20

Small-scale

0.665

High

1007625

H11
Histone H1.1

3

7

Small-scale

0.655

High

442665

RB
Retinoblastoma-associated protein

2

7

Small-scale

0.629

High

519481

MYBB
Myb-related protein B

2

2

Small-scale

0.629

High

1007624

E2F1
Transcription factor E2F1

2

9

Small-scale

0.629

High

755684

MCM4
DNA replication licensing factor MCM4

2

3

Small-scale

0.619

High

877085

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.618

High

885745

KC1E
Casein kinase I isoform epsilon

1

4

High-throughput

0.618

High

1007637

CUL1
Cullin-1

2

3

Small-scale

0.611

High

595392

H15
Histone H1.5

2

7

Small-scale

0.602

High

241375

PRKN
E3 ubiquitin-protein ligase parkin

2

3

Small-scale

0.601

High

719128

MPIP1
M-phase inducer phosphatase 1

2

8

Small-scale

0.584

High

258273

TRI13
E3 ubiquitin-protein ligase TRIM13

1

1

Small-scale

0.561

High

904273

BRCA2
Breast cancer type 2 susceptibility protein

1

2

Small-scale

0.561

High

1007629

INCA1
Protein INCA1

1

0

Small-scale

0.549

High

1007631

GPS2
G protein pathway suppressor 2

1

0

Small-scale

0.549

High

1007639

MCM6
DNA replication licensing factor MCM6

1

5

High-throughput

0.536

High

1007643

CSN6
COP9 signalosome complex subunit 6

1

6

High-throughput

0.536

High

1007650

CSN5
COP9 signalosome complex subunit 5

1

6

High-throughput

0.536

High

442919

PRGR
Progesterone receptor

1

0

Small-scale

0.529

High

1007644

CCAR2
Cell cycle and apoptosis regulator protein 2

1

1

High-throughput

0.515

High

992687

RACK1
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.504

High

464904

SP1
Transcription factor Sp1

1

2

Small-scale

0.501

High

681150

PSA2
Proteasome subunit alpha type-2

1

2

Small-scale

0.501

High

695195

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

Small-scale

0.501

High

704936

RBL1
Retinoblastoma-like protein 1

1

7

Small-scale

0.501

High

753912

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

20

Small-scale

0.501

High

814783

CUX1
Homeobox protein cut-like 1

1

2

Small-scale

0.501

High

956644

CKS1
Cyclin-dependent kinases regulatory subunit 1

1

20

Small-scale

0.501

High

1007627

RBL2
Retinoblastoma-like protein 2

1

7

Small-scale

0.501

High

1007651

H2B1A
Histone H2B type 1-A

1

1

Small-scale

0.501

High

1007659

APC4
Anaphase-promoting complex subunit 4

1

2

Small-scale

0.501

High

212718

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

0

High-throughput

0.493

High

659440

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.493

High

557222

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

Small-scale

0.481

High

558031

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.481

High

1007654

RBM4
RNA-binding protein 4

1

1

Small-scale

0.481

High

1007638

NPAT
Protein NPAT

1

0

Small-scale

0.480

High

131399

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

6

High-throughput

0.479

High

288388

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

2

Small-scale

0.479

High

669871

MCM3
DNA replication licensing factor MCM3

1

5

High-throughput

0.479

High

764652

CTNB1
Catenin beta-1

1

5

Small-scale

0.479

High

887966

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.479

High

967663

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

High-throughput

0.479

High

977460

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

6

High-throughput

0.479

High

1007626

FAK1
Focal adhesion kinase 1

1

3

High-throughput

0.479

High

1007628

EP300
Histone acetyltransferase p300

1

6

Small-scale

0.479

High

1007632

TIF1B
Transcription intermediary factor 1-beta

1

4

High-throughput

0.479

High

1007634

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.479

High

1007641

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

5

High-throughput

0.479

High

1007648

ATX2L
Ataxin-2-like protein

1

1

High-throughput

0.479

High

1007649

LAR4B
La-related protein 4B

1

2

High-throughput

0.479

High

1007656

XPO5
Exportin-5

1

4

High-throughput

0.479

High

1007662

EXO1
Exonuclease 1

1

6

Small-scale

0.479

High

1007663

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

1

Small-scale

0.479

High

176662

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

405271

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

547589

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.458

High

646820

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.458

High

697070

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

822603

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

841681

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

915063

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.458

High

920782

ACLY
ATP-citrate synthase

1

0

High-throughput

0.458

High

938204

SEC13
Protein SEC13 homolog

1

0

High-throughput

0.458

High

1007652

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1007653

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

0

High-throughput

0.458

High

1007658

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.458

High

1007647

MIPT3
TRAF3-interacting protein 1

1

1

High-throughput

0.457

High

1007635

ORC1
Origin recognition complex subunit 1

1

7

Small-scale

0.445

High

1007636

ORC2
Origin recognition complex subunit 2

1

3

Small-scale

0.445

High

882620

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.437

High

1007660

STML2
Stomatin-like protein 2, mitochondrial

1

2

High-throughput

0.437

High

1007642

SMTL2
Smoothelin-like protein 2

1

1

High-throughput

0.407

High

1007645

PRCA1
Protein PROCA1

1

0

Small-scale

0.275

Low

1007657

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

0

High-throughput

0.269

Low

1007646

KLDC9
Kelch domain-containing protein 9

1

0

Small-scale

0.251

Low

362027

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.249

Low

1007640

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025