Protein: UBE2C
Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (UbcH10) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C)

Gene: UBE2C
Organism: Homo sapiens
Interactions: 56
UniProt ID: O00762

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

135955

APC11
Anaphase-promoting complex subunit 11

64

20

Small-scale

0.997

High

135909

UBE2C
Ubiquitin-conjugating enzyme E2 C

5

17

Small-scale

0.924

High

135923

UBA1
Ubiquitin-like modifier-activating enzyme 1

5

20

Small-scale

0.919

High

135956

RBX2
RING-box protein 2

4

20

Small-scale

0.899

High

135959

ANC2
Anaphase-promoting complex subunit 2

4

20

Small-scale

0.896

High

135932

CDC20
Cell division cycle protein 20 homolog

4

7

Small-scale

0.888

High

135960

FZR1
Fizzy-related protein homolog

4

7

Small-scale

0.885

High

135917

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

20

Small-scale

0.834

High

135911

PRKN
E3 ubiquitin-protein ligase parkin

2

20

Small-scale

0.768

High

135941

DTX1
E3 ubiquitin-protein ligase DTX1

1

20

High-throughput

0.698

High

135929

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.665

High

135938

PCGF3
Polycomb group RING finger protein 3

1

20

High-throughput

0.656

High

135933

MK07
Mitogen-activated protein kinase 7

3

3

High-throughput

0.654

High

135920

RAG1
V(D)J recombination-activating protein 1

1

20

Small-scale

0.647

High

135922

RO52
E3 ubiquitin-protein ligase TRIM21

1

20

Small-scale

0.647

High

135927

TRI23
E3 ubiquitin-protein ligase TRIM23

1

18

Small-scale

0.647

High

135934

TIF1B
Transcription intermediary factor 1-beta

1

20

Small-scale

0.647

High

135939

HECD3
E3 ubiquitin-protein ligase HECTD3

1

20

Small-scale

0.647

High

135942

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

7

Small-scale

0.647

High

135947

RNF31
E3 ubiquitin-protein ligase RNF31

1

20

Small-scale

0.647

High

135948

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

20

Small-scale

0.647

High

135951

TRIM2
Tripartite motif-containing protein 2

1

20

Small-scale

0.647

High

135952

RN167
E3 ubiquitin-protein ligase RNF167

1

20

Small-scale

0.647

High

135961

CHIP
E3 ubiquitin-protein ligase CHIP

1

14

Small-scale

0.647

High

135962

RNF6
E3 ubiquitin-protein ligase RNF6

1

20

Small-scale

0.647

High

135919

PVR
Poliovirus receptor

2

3

High-throughput

0.628

High

135937

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

17

Small-scale

0.618

High

135943

RN133
E3 ubiquitin-protein ligase RNF133

1

20

Small-scale

0.618

High

135958

HERC5
E3 ISG15--protein ligase HERC5

1

20

Small-scale

0.618

High

135945

RYR2
Ryanodine receptor 2

1

10

Small-scale

0.561

High

135963

SAR1B
Small COPII coat GTPase SAR1B

1

2

High-throughput

0.536

High

135916

ENOG
Gamma-enolase

1

0

High-throughput

0.518

High

135924

CXCR1
C-X-C chemokine receptor type 1

1

0

High-throughput

0.518

High

135930

TNNC1
Troponin C, slow skeletal and cardiac muscles

1

0

High-throughput

0.518

High

135910

AURKA
Aurora kinase A

1

3

Small-scale

0.501

High

135925

PSB5
Proteasome subunit beta type-5

1

5

Small-scale

0.501

High

135926

PRS7
26S proteasome regulatory subunit 7

1

1

Small-scale

0.501

High

135928

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

2

Small-scale

0.501

High

135931

TF65
Transcription factor p65

1

7

Small-scale

0.501

High

135953

DPOLM
DNA-directed DNA/RNA polymerase mu

1

8

Small-scale

0.501

High

135913

KLHL2
Kelch-like protein 2

1

7

High-throughput

0.481

High

135940

UBE3D
E3 ubiquitin-protein ligase E3D

1

0

Small-scale

0.480

High

135912

BRD4
Bromodomain-containing protein 4

1

8

High-throughput

0.479

High

135914

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.479

High

135915

EGFR
Epidermal growth factor receptor

1

4

Small-scale

0.479

High

135921

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

135946

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.479

High

135954

RN216
E3 ubiquitin-protein ligase RNF216

1

20

Small-scale

0.479

High

135957

DUX4
Double homeobox protein 4

1

1

High-throughput

0.479

High

135936

PAF15
PCNA-associated factor

1

0

Small-scale

0.458

High

135935

TRI29
Tripartite motif-containing protein 29

1

20

Small-scale

0.457

High

135949

RANB9
Ran-binding protein 9

1

10

High-throughput

0.457

High

135918

CADH1
Cadherin-1

1

0

Small-scale

0.426

High

135950

EBP2
Probable rRNA-processing protein EBP2

1

1

High-throughput

0.417

High

135944

CKAP2
Cytoskeleton-associated protein 2

1

0

Small-scale

0.261

Low


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Last updated: 15 Jul 2024