HitPredict

Interactor 1: PTPRA (P18052)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)
Gene: PTPRA

Interactor 2: PTPRM (P28828)
Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)
Gene: PTPRM

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	10777529
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Y_phosphatase~Y_phosphatase
Common GO terms	GO:0004725 - protein tyrosine phosphatase activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 829 Mm			1 1452
+	Mm
		573997 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRA_MOUSE (731-1451): 0: 711: 31.07
+	Hs
		576980 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRA_HUMAN (696-1451): 0: 723: 32.08
+	Mm
		574010 PTPRA_MOUSE (1-829): 0: 1004: 100.00		S4R1M0_MOUSE (205-1215): 4.5e-79: 287: 14.52
+	Mm
		574008 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRD_MOUSE (12-951): 3.05e-76: 282: 12.30
+	Mm
		574002 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRE_MOUSE (576-1155): 4.82e-78: 275: 20.44
+	Hs
		576983 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRE_HUMAN (576-1155): 4.08e-79: 278: 19.83
+	Mm
		56906 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRF_MOUSE (1-856): 5.49e-59: 226: 13.94
+	Mm
		69645 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRS_MOUSE (182-951): 1.58e-55: 215: 11.83
+	Mm
		69654 PTPRS_MOUSE (5-827): 0: 887: 36.26		S4R1M0_MOUSE (205-1215): 4.5e-79: 287: 14.52
+	Hs
		616971 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRD_HUMAN (12-951): 2.68e-76: 282: 12.70
+	Hs
		1031977 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRS_HUMAN (12-951): 4.57e-76: 281: 11.89
+	Hs
		616939 PTPRD_HUMAN (14-827): 0: 885: 37.97		PTPRD_HUMAN (12-951): 2.68e-76: 282: 12.70
+	Mm
		828098 PTPRD_MOUSE (14-827): 0: 890: 37.85		PTPRE_MOUSE (576-1155): 4.82e-78: 275: 20.44
+	Mm
		69646 PTPRS_MOUSE (5-827): 0: 887: 36.26		PTPRE_MOUSE (576-1155): 4.82e-78: 275: 20.44
+	Hs
		576984 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRG_HUMAN (681-1160): 1.92e-44: 179: 18.02
+	Hs
		489957 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRF_HUMAN (1-856): 2.51e-59: 227: 14.16
+	Hs
		616916 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRB_HUMAN (358-973): 1.11e-11: 72.3: 10.63