Interactor 1: ERCC2 (P18074)
General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein)
Gene: ERCC2

Interactor 2: TF2H5 (Q6ZYL4)
General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) (TFIIH subunit p8)
Gene: GTF2H5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 0.55 0.592

The method score is based on:

Property Details
Experiments 26496610, 19172752
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000439 - transcription factor TFIIH core complex
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0005675 - transcription factor TFIIH holo complex
and 5 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024