Protein: RSMN
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)

Gene: RSMN, SNRPN
Organism: Homo sapiens
Interactions: 191
UniProt ID: P63162

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0005682 - U5 snRNP

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

974715

SMD3
Small nuclear ribonucleoprotein Sm D3

4

19

Small-scale

0.897

High

167081

GEMI2
Gem-associated protein 2

3

1

Small-scale

0.866

High

215074

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

3

2

High-throughput

0.861

High

472615

RU17
U1 small nuclear ribonucleoprotein 70 kDa

3

9

High-throughput

0.861

High

485607

RU2A
U2 small nuclear ribonucleoprotein A'

3

4

High-throughput

0.861

High

991180

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

3

4

High-throughput

0.861

High

991203

PRP8
Pre-mRNA-processing-splicing factor 8

3

3

High-throughput

0.861

High

991277

LSM4
U6 snRNA-associated Sm-like protein LSm4

3

19

High-throughput

0.861

High

574210

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

6

High-throughput

0.847

High

286447

WBP4
WW domain-binding protein 4

2

8

High-throughput

0.811

High

344531

LSM8
U6 snRNA-associated Sm-like protein LSm8

2

17

High-throughput

0.811

High

480088

RU1C
U1 small nuclear ribonucleoprotein C

2

4

High-throughput

0.811

High

926167

ICLN
Methylosome subunit pICln

2

3

High-throughput

0.811

High

973687

RUXE
Small nuclear ribonucleoprotein E

2

3

High-throughput

0.811

High

973880

RUXF
Small nuclear ribonucleoprotein F

2

17

High-throughput

0.811

High

974355

SMD1
Small nuclear ribonucleoprotein Sm D1

2

19

High-throughput

0.811

High

974520

SMD2
Small nuclear ribonucleoprotein Sm D2

2

6

High-throughput

0.811

High

991170

SF3A3
Splicing factor 3A subunit 3

2

2

High-throughput

0.811

High

991177

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

2

12

High-throughput

0.811

High

991252

PKRI1
PRKR-interacting protein 1

2

1

High-throughput

0.811

High

991274

LSM2
U6 snRNA-associated Sm-like protein LSm2

2

18

High-throughput

0.811

High

974112

RUXG
Small nuclear ribonucleoprotein G

2

19

High-throughput

0.789

High

991266

ZMAT5
Zinc finger matrin-type protein 5

2

0

High-throughput

0.770

High

335811

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

5

4

Small-scale

0.717

High

991207

MEPCE
7SK snRNA methylphosphate capping enzyme

4

1

High-throughput

0.694

High

974310

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

16

High-throughput

0.691

High

991276

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

16

High-throughput

0.691

High

477988

SNRPA
U1 small nuclear ribonucleoprotein A

3

10

High-throughput

0.669

High

991265

TFP11
Tuftelin-interacting protein 11

3

4

High-throughput

0.669

High

225274

HTSF1
17S U2 SnRNP complex component HTATSF1

3

10

High-throughput

0.667

High

285866

SF3B1
Splicing factor 3B subunit 1

3

6

High-throughput

0.667

High

471812

RU2B
U2 small nuclear ribonucleoprotein B''

3

10

High-throughput

0.667

High

991236

RIOK1
Serine/threonine-protein kinase RIO1

3

2

High-throughput

0.667

High

162535

ANM5
Protein arginine N-methyltransferase 5

2

7

High-throughput

0.628

High

209243

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

2

8

High-throughput

0.628

High

245085

AQR
RNA helicase aquarius

2

6

High-throughput

0.628

High

250988

PRP17
Pre-mRNA-processing factor 17

2

10

High-throughput

0.628

High

286768

SKAP2
Src kinase-associated phosphoprotein 2

2

8

High-throughput

0.628

High

289495

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

2

16

High-throughput

0.628

High

321494

PRP6
Pre-mRNA-processing factor 6

2

11

High-throughput

0.628

High

326826

SPN1
Snurportin-1

2

2

High-throughput

0.628

High

351321

SYF2
Pre-mRNA-splicing factor SYF2

2

1

High-throughput

0.628

High

799841

COIL
Coilin

2

2

High-throughput

0.628

High

833525

BUD31
Protein BUD31 homolog

2

2

High-throughput

0.628

High

991166

LSM11
U7 snRNA-associated Sm-like protein LSm11

2

1

High-throughput

0.628

High

991167

TXN4A
Thioredoxin-like protein 4A

2

2

High-throughput

0.628

High

991169

CSTF1
Cleavage stimulation factor subunit 1

2

10

High-throughput

0.628

High

991173

SF3B2
Splicing factor 3B subunit 2

2

2

High-throughput

0.628

High

991183

SF3B4
Splicing factor 3B subunit 4

2

8

High-throughput

0.628

High

991184

SF3A2
Splicing factor 3A subunit 2

2

6

High-throughput

0.628

High

991185

SF3A1
Splicing factor 3A subunit 1

2

6

High-throughput

0.628

High

991186

U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

2

5

High-throughput

0.628

High

991189

U1SBP
U11/U12 small nuclear ribonucleoprotein 35 kDa protein

2

8

High-throughput

0.628

High

991192

C19L2
CWF19-like protein 2

2

3

High-throughput

0.628

High

991196

EAPP
E2F-associated phosphoprotein

2

1

High-throughput

0.628

High

991202

SNR48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein

2

2

High-throughput

0.628

High

991204

DPP8
Dipeptidyl peptidase 8

2

2

High-throughput

0.628

High

991210

CMTR2
Cap-specific mRNA

2

2

High-throughput

0.628

High

991211

PDCD7
Programmed cell death protein 7

2

1

High-throughput

0.628

High

991214

GEMI5
Gem-associated protein 5

2

4

High-throughput

0.628

High

991215

CCD12
Coiled-coil domain-containing protein 12

2

1

High-throughput

0.628

High

991217

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

3

High-throughput

0.628

High

991224

TOE1
Target of EGR1 protein 1

2

1

High-throughput

0.628

High

991227

RNPC3
RNA-binding region-containing protein 3

2

8

High-throughput

0.628

High

991230

TGS1
Trimethylguanosine synthase

2

2

High-throughput

0.628

High

991234

MEP50
Methylosome protein WDR77

2

10

High-throughput

0.628

High

991235

GPTC1
G patch domain-containing protein 1

2

4

High-throughput

0.628

High

991237

WDR83
WD repeat domain-containing protein 83

2

10

High-throughput

0.628

High

991239

DDX23
Probable ATP-dependent RNA helicase DDX23

2

9

High-throughput

0.628

High

991241

NADAP
Kanadaptin

2

4

High-throughput

0.628

High

991244

CRNL1
Crooked neck-like protein 1

2

14

High-throughput

0.628

High

991250

DHX35
Probable ATP-dependent RNA helicase DHX35

2

11

High-throughput

0.628

High

991251

STPAP
Speckle targeted PIP5K1A-regulated poly(A) polymerase

2

1

High-throughput

0.628

High

991256

SYF1
Pre-mRNA-splicing factor SYF1

2

13

High-throughput

0.628

High

991257

COPRS
Coordinator of PRMT5 and differentiation stimulator

2

1

High-throughput

0.628

High

991262

GEMI8
Gem-associated protein 8

2

1

High-throughput

0.628

High

991278

PAXB1
PAX3- and PAX7-binding protein 1

2

2

High-throughput

0.628

High

991279

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

2

1

High-throughput

0.628

High

991172

CTBP1
C-terminal-binding protein 1

2

1

High-throughput

0.613

High

944448

GEMI4
Gem-associated protein 4

2

1

High-throughput

0.611

High

991273

AAR2
Protein AAR2 homolog

2

2

High-throughput

0.611

High

991216

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.602

High

991222

ESS2
Splicing factor ESS-2 homolog

2

0

High-throughput

0.602

High

991270

UTP16
U3 small nucleolar RNA-associated protein NOL7

2

0

High-throughput

0.602

High

979469

H4
Histone H4

2

2

High-throughput

0.584

High

991194

LARP7
La-related protein 7

2

5

High-throughput

0.584

High

71570

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

19

High-throughput

0.575

High

291995

CRTAP
Cartilage-associated protein

2

1

High-throughput

0.574

High

991212

GPT11
G patch domain-containing protein 11

2

1

High-throughput

0.574

High

991271

E41L3
Band 4.1-like protein 3

2

7

High-throughput

0.574

High

991275

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

2

6

High-throughput

0.574

High

631158

RAB5A
Ras-related protein Rab-5A

2

2

High-throughput

0.571

High

991188

MK14
Mitogen-activated protein kinase 14

2

3

High-throughput

0.571

High

991263

AKA7G
A-kinase anchor protein 7 isoform gamma

2

3

High-throughput

0.558

High

413582

P53
Cellular tumor antigen p53

1

3

High-throughput

0.541

High

886261

ARL4D
ADP-ribosylation factor-like protein 4D

1

2

High-throughput

0.541

High

991176

KEAP1
Kelch-like ECH-associated protein 1

1

4

High-throughput

0.541

High

991233

SH3G3
Endophilin-A3

1

20

High-throughput

0.541

High

991260

RFOX1
RNA binding protein fox-1 homolog 1

1

8

High-throughput

0.541

High

212201

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

3

High-throughput

0.536

High

297957

SPF27
Pre-mRNA-splicing factor SPF27

1

1

High-throughput

0.536

High

938335

NH2L1
NHP2-like protein 1

1

3

High-throughput

0.536

High

991174

TRA2A
Transformer-2 protein homolog alpha

1

5

High-throughput

0.536

High

991190

SMN
Survival motor neuron protein

1

5

High-throughput

0.536

High

991193

P3H1
Prolyl 3-hydroxylase 1

1

1

High-throughput

0.536

High

991218

GEMI6
Gem-associated protein 6

1

1

High-throughput

0.536

High

991238

RBM42
RNA-binding protein 42

1

7

High-throughput

0.536

High

991240

SF3B5
Splicing factor 3B subunit 5

1

3

High-throughput

0.536

High

991268

DDX20
Probable ATP-dependent RNA helicase DDX20

1

12

High-throughput

0.536

High

991269

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

2

High-throughput

0.536

High

463051

YES
Tyrosine-protein kinase Yes

2

8

High-throughput

0.521

High

193335

MAFG
Transcription factor MafG

1

0

High-throughput

0.518

High

563589

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

991187

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.515

High

991242

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

6

High-throughput

0.494

High

991178

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

991199

MTCL3
Microtubule cross-linking factor 3

1

6

High-throughput

0.489

High

336648

BAG4
BAG family molecular chaperone regulator 4

1

1

High-throughput

0.481

High

991195

CEP55
Centrosomal protein of 55 kDa

1

2

High-throughput

0.481

High

991220

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.481

High

991221

EXOS8
Exosome complex component RRP43

1

2

High-throughput

0.481

High

991165

GTF2I
General transcription factor II-I

1

0

Small-scale

0.480

High

291773

STK16
Serine/threonine-protein kinase 16

1

1

High-throughput

0.479

High

302702

SYUG
Gamma-synuclein

1

4

High-throughput

0.479

High

324755

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

371705

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

395862

ESR1
Estrogen receptor

1

2

Small-scale

0.479

High

558024

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

620283

NUCL
Nucleolin

1

2

High-throughput

0.479

High

660599

IF4B
Eukaryotic translation initiation factor 4B

1

1

Small-scale

0.479

High

730494

1433S
14-3-3 protein sigma

1

5

Small-scale

0.479

High

731186

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

754788

H2B1B
Histone H2B type 1-B

1

13

High-throughput

0.479

High

889545

CLK2
Dual specificity protein kinase CLK2

1

4

High-throughput

0.479

High

905370

HCFC1
Host cell factor 1

1

2

Small-scale

0.479

High

937206

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

5

Small-scale

0.479

High

955041

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.479

High

988259

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.479

High

991171

REST
RE1-silencing transcription factor

1

1

High-throughput

0.479

High

991175

CUL4B
Cullin-4B

1

8

High-throughput

0.479

High

991179

TNIP1
TNFAIP3-interacting protein 1

1

9

High-throughput

0.479

High

991182

SF3B3
Splicing factor 3B subunit 3

1

3

High-throughput

0.479

High

991198

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

991206

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

991209

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

991213

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

991219

RENT1
Regulator of nonsense transcripts 1

1

3

Small-scale

0.479

High

991223

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.479

High

991226

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

991231

CRBN
Protein cereblon

1

1

Small-scale

0.479

High

991232

RING2
E3 ubiquitin-protein ligase RING2

1

6

High-throughput

0.479

High

991245

TRI31
E3 ubiquitin-protein ligase TRIM31

1

8

High-throughput

0.479

High

991247

GAN
Gigaxonin

1

3

High-throughput

0.479

High

991249

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.479

High

991254

RC3H2
Roquin-2

1

7

High-throughput

0.479

High

991261

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

991264

IBTK
Inhibitor of Bruton tyrosine kinase

1

1

High-throughput

0.479

High

991267

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

991272

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

1

Small-scale

0.479

High

991197

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

991259

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

128949

MEN1
Menin

1

0

High-throughput

0.458

High

194123

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

257431

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

991181

ELOC
Elongin-C

1

0

High-throughput

0.458

High

991201

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

991208

VRK3
Serine/threonine-protein kinase VRK3

1

0

High-throughput

0.458

High

991229

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

991246

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

991258

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

991200

RIF1
Telomere-associated protein RIF1

1

6

High-throughput

0.457

High

991205

GGYF2
GRB10-interacting GYF protein 2

1

6

Small-scale

0.457

High

991280

X5D7T5
RNA binding protein fox-1 homolog

1

7

High-throughput

0.457

High

529575

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.445

High

991253

LN28A
Protein lin-28 homolog A

1

4

High-throughput

0.445

High

991228

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

1

High-throughput

0.439

High

353230

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

411715

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.437

High

580980

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.437

High

910005

RND2
Rho-related GTP-binding protein RhoN

1

17

High-throughput

0.437

High

953385

RAC3
Ras-related C3 botulinum toxin substrate 3

1

13

High-throughput

0.437

High

961936

RHOA
Transforming protein RhoA

1

14

High-throughput

0.437

High

962701

RND3
Rho-related GTP-binding protein RhoE

1

17

High-throughput

0.437

High

977920

RHOB
Rho-related GTP-binding protein RhoB

1

14

High-throughput

0.437

High

991168

RHOG
Rho-related GTP-binding protein RhoG

1

11

High-throughput

0.437

High

991191

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

991225

RHOV
Rho-related GTP-binding protein RhoV

1

14

High-throughput

0.437

High

991243

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

991248

RHOJ
Rho-related GTP-binding protein RhoJ

1

15

High-throughput

0.437

High

991255

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.437

High

224419

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

1

3

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025