HitPredict

Interactor 1: BMP7 (P18075)
Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa)
Gene: BMP7

Interactor 2: KRA59 (P26371)
Keratin-associated protein 5-9 (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (Keratin-associated protein 5.9) (UHS keratin A) (UHS KerA) (Ultrahigh sulfur keratin-associated protein 5.9)
Gene: KRTAP5-9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.597

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 169
+	Hs
		66517 A8K571_HUMAN (1-431): 0: 536: 100.00		KRA59_HUMAN (1-169): 2.65e-53: 168: 100.00
+	Hs
		574220 BMP7_HUMAN (1-431): 0: 536: 100.00		KRA13_HUMAN (8-166): 8.07e-21: 85.5: 26.25
+	Hs
		574191 BMP7_HUMAN (1-431): 0: 536: 100.00		KR109_HUMAN (39-168): 9.93e-17: 77.1: 26.14
+	Hs
		66518 A8K571_HUMAN (1-431): 0: 536: 100.00		KR105_HUMAN (6-165): 3.51e-16: 75.5: 26.06
+	Hs
		574188 BMP7_HUMAN (1-431): 0: 536: 100.00		KR103_HUMAN (22-166): 2.09e-16: 75.1: 26.12
+	Hs
		574190 BMP7_HUMAN (1-431): 0: 536: 100.00		KR108_HUMAN (26-165): 4.36e-14: 69.4: 28.87
+	Hs
		66520 A8K571_HUMAN (1-431): 0: 536: 100.00		KR108_HUMAN (26-165): 4.36e-14: 69.4: 28.87
+	Hs
		574227 BMP7_HUMAN (1-431): 0: 536: 100.00		KRA98_HUMAN (52-167): 1.94e-11: 60.5: 35.04
+	Hs
		574189 BMP7_HUMAN (1-431): 0: 536: 100.00		KR107_HUMAN (26-165): 1.87e-09: 57: 25.30
+	Hs
		66519 A8K571_HUMAN (1-431): 0: 536: 100.00		KR107_HUMAN (26-165): 1.87e-09: 57: 25.30
+	Hs
		574187 BMP7_HUMAN (1-431): 0: 536: 100.00		KR123_HUMAN (6-98): 8.5e-10: 54.7: 23.16
+	Hs
		351412 TGFB1_HUMAN (30-430): 3.2e-82: 259: 20.10		KRA13_HUMAN (8-166): 8.07e-21: 85.5: 26.25
+	Hs
		351256 TGFB1_HUMAN (30-430): 3.2e-82: 259: 20.10		TENX_HUMAN (1-167): 2.47e-15: 74.4: 19.23
+	Hs
		351361 TGFB1_HUMAN (30-430): 3.2e-82: 259: 20.10		KRA11_HUMAN (31-167): 3.12e-15: 71.3: 30.44
+	Hs
		351325 TGFB1_HUMAN (30-430): 3.2e-82: 259: 20.10		KR108_HUMAN (26-165): 4.36e-14: 69.4: 28.87
+	Hs
		351450 TGFB1_HUMAN (30-430): 3.2e-82: 259: 20.10		KR411_HUMAN (1-131): 4.08e-12: 63.2: 25.19