Protein: RSMB
Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB)

Gene: RSMB, SMB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 128
UniProt ID: P40018

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817120

SMD3
Small nuclear ribonucleoprotein Sm D3

8

16

Small-scale

0.964

High

817148

SMD1
Small nuclear ribonucleoprotein Sm D1

7

5

Small-scale

0.960

High

817176

RU2A
U2 small nuclear ribonucleoprotein A'

6

3

Small-scale

0.940

High

817146

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

6

9

Small-scale

0.937

High

751744

PRP8
Pre-mRNA-splicing factor 8

5

2

High-throughput

0.922

High

817174

LUC7
Protein LUC7

5

1

High-throughput

0.919

High

817116

RUXG
Small nuclear ribonucleoprotein G

5

14

High-throughput

0.912

High

817141

RUXF
Small nuclear ribonucleoprotein F

5

5

High-throughput

0.912

High

817142

LSM3
LSM complex subunit LSM3

5

19

Small-scale

0.908

High

817114

LSM4
LSM complex subunit LSM4

4

6

Small-scale

0.894

High

780179

SN114
Pre-mRNA-splicing factor SNU114

4

3

High-throughput

0.892

High

817165

SMD2
Small nuclear ribonucleoprotein Sm D2

4

4

High-throughput

0.892

High

625098

PRP9
Pre-mRNA-splicing factor PRP9

4

2

High-throughput

0.886

High

817122

LSM8
LSM2-LSM8 complex subunit LSM8

4

15

High-throughput

0.881

High

817162

RU1C
U1 small nuclear ribonucleoprotein C

5

0

High-throughput

0.875

High

795872

LSM2
LSM complex subunit LSM2

3

16

High-throughput

0.847

High

817152

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

3

2

High-throughput

0.847

High

817182

RUXE
Small nuclear ribonucleoprotein E

3

3

High-throughput

0.839

High

744116

BRR2
Pre-mRNA-splicing helicase BRR2

8

12

Small-scale

0.745

High

817149

CUS1
Cold sensitive U2 snRNA suppressor 1

6

2

High-throughput

0.730

High

817144

NAM8
Protein NAM8

5

3

High-throughput

0.712

High

817172

PRP11
Pre-mRNA-splicing factor PRP11

5

2

High-throughput

0.712

High

817155

CEF1
Pre-mRNA-splicing factor CEF1

5

2

Small-scale

0.709

High

743526

RU1A
U1 small nuclear ribonucleoprotein A

6

0

Small-scale

0.702

High

817177

CWC2
Pre-mRNA-splicing factor CWC2

4

6

High-throughput

0.694

High

625014

PRP6
Pre-mRNA-splicing factor 6

4

9

High-throughput

0.691

High

627850

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

4

6

High-throughput

0.691

High

750253

PRP40
Pre-mRNA-processing protein PRP40

4

4

High-throughput

0.691

High

817125

PRP31
Pre-mRNA-processing factor 31

4

2

High-throughput

0.691

High

739247

PRP21
Pre-mRNA-splicing factor PRP21

4

2

High-throughput

0.686

High

757494

NCBP1
Nuclear cap-binding protein complex subunit 1

4

1

High-throughput

0.686

High

813355

PRP39
Pre-mRNA-processing factor 39

4

12

High-throughput

0.686

High

817126

SF3B1
U2 snRNP component HSH155

4

3

High-throughput

0.686

High

817161

RSE1
Pre-mRNA-splicing factor RSE1

4

3

High-throughput

0.686

High

817175

NCBP2
Nuclear cap-binding protein subunit 2

4

4

High-throughput

0.686

High

817181

CLF1
Pre-mRNA-splicing factor CLF1

4

12

Small-scale

0.686

High

817187

HSH49
Protein HSH49

4

4

High-throughput

0.686

High

797306

SP381
Pre-mRNA-splicing factor SPP381

5

0

High-throughput

0.684

High

739147

PRP19
Pre-mRNA-processing factor 19

4

5

Small-scale

0.683

High

817185

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

4

2

Small-scale

0.683

High

817159

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

5

0

High-throughput

0.682

High

817130

SNU71
U1 small nuclear ribonucleoprotein component SNU71

5

0

Small-scale

0.678

High

817163

SN309
Pre-mRNA-splicing factor SNT309

4

0

High-throughput

0.664

High

403523

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

3

2

Small-scale

0.656

High

817118

MSL1
U2 small nuclear ribonucleoprotein B''

3

9

High-throughput

0.656

High

817158

PRP42
U1 small nuclear ribonucleoprotein component PRP42

3

14

High-throughput

0.656

High

817160

SYF1
Pre-mRNA-splicing factor SYF1

3

12

High-throughput

0.656

High

817170

DIB1
Spliceosomal protein DIB1

3

2

High-throughput

0.656

High

817184

PRP46
Pre-mRNA-splicing factor PRP46

3

4

High-throughput

0.656

High

817129

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

7

High-throughput

0.650

High

817167

SP382
Pre-mRNA-splicing factor SPP382

3

0

High-throughput

0.638

High

817183

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

3

0

High-throughput

0.628

High

817115

LSM5
LSM complex subunit LSM5

1

2

High-throughput

0.618

High

817139

LSM7
LSM complex subunit LSM7

1

14

High-throughput

0.618

High

817166

LSM6
LSM complex subunit LSM6

1

5

High-throughput

0.618

High

817153

CWC21
Pre-mRNA-splicing factor CWC21

3

0

Small-scale

0.613

High

735458

AAR2
A1 cistron-splicing factor AAR2

2

2

High-throughput

0.611

High

817178

TGS1
Trimethylguanosine synthase

2

2

Small-scale

0.595

High

817186

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.586

High

817127

CWC23
Pre-mRNA-splicing factor CWC23

2

0

High-throughput

0.585

High

638061

ISY1
Pre-mRNA-splicing factor ISY1

2

2

High-throughput

0.584

High

700105

PRP45
Pre-mRNA-processing protein 45

2

1

High-throughput

0.584

High

796441

SLT11
Pre-mRNA-splicing factor SLT11

2

1

High-throughput

0.584

High

817119

PRP17
Pre-mRNA-processing factor 17

2

6

High-throughput

0.584

High

817171

RDS3
Pre-mRNA-splicing factor RDS3

2

1

High-throughput

0.571

High

702249

YJU2
Splicing factor YJU2

2

0

High-throughput

0.559

High

781558

NTR2
Pre-mRNA-splicing factor NTR2

2

0

High-throughput

0.559

High

817132

SYF2
Pre-mRNA-splicing factor SYF2

2

0

High-throughput

0.559

High

817134

CWC22
Pre-mRNA-splicing factor CWC22

2

0

High-throughput

0.559

High

817145

PRP38
Pre-mRNA-splicing factor 38

2

0

High-throughput

0.559

High

817157

CWC15
Pre-mRNA-splicing factor CWC15

2

0

High-throughput

0.559

High

738212

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

2

3

High-throughput

0.537

High

792071

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.536

High

815128

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.536

High

453955

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

794707

SEA4
SEH-associated protein 4

1

0

High-throughput

0.513

High

817123

CSN12
Cop9 signalosome complex subunit 12

1

0

High-throughput

0.513

High

817168

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.513

High

664595

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

8

Small-scale

0.501

High

817128

SEH1
Nucleoporin SEH1

1

3

High-throughput

0.489

High

740524

SIP1
SNF1 protein kinase subunit beta-1

1

0

High-throughput

0.486

High

817136

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.486

High

817138

SWT21
Protein SWT21

1

0

High-throughput

0.486

High

444526

DED1
ATP-dependent RNA helicase DED1

1

3

High-throughput

0.479

High

594387

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

Small-scale

0.479

High

603057

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

628207

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

8

High-throughput

0.479

High

638011

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

5

High-throughput

0.479

High

672055

BUD31
Pre-mRNA-splicing factor BUD31

1

2

High-throughput

0.479

High

682292

SPB4
ATP-dependent rRNA helicase SPB4

1

5

High-throughput

0.479

High

738851

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.479

High

740932

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

7

High-throughput

0.479

High

751408

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.479

High

751964

LHP1
La protein homolog

1

3

High-throughput

0.479

High

805591

LSM12
Protein LSM12

1

2

High-throughput

0.479

High

806011

LIN1
Protein LIN1

1

3

High-throughput

0.479

High

816507

SNU13
13 kDa ribonucleoprotein-associated protein

1

3

High-throughput

0.479

High

817135

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.479

High

817147

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.479

High

817150

CWC27
Peptidyl-prolyl isomerase CWC27

1

5

High-throughput

0.479

High

817154

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

1

High-throughput

0.479

High

817156

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

2

High-throughput

0.479

High

817179

YRA1
RNA annealing protein YRA1

1

5

High-throughput

0.479

High

817180

BBP
Branchpoint-bridging protein

1

3

Small-scale

0.479

High

501741

YSF3
RDS3 complex subunit 10

1

0

High-throughput

0.458

High

707199

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

709784

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

797673

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

797745

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

808827

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

817117

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

817121

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.458

High

817133

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

817137

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.458

High

817151

IMA1
Importin subunit alpha

1

0

High-throughput

0.458

High

817164

IMB1
Importin subunit beta-1

1

0

High-throughput

0.458

High

817173

PBP4
Protein PBP4

1

0

High-throughput

0.458

High

817188

MTR10
mRNA transport regulator MTR10

1

0

Small-scale

0.458

High

545006

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

817143

SEN1
Helicase SEN1

1

4

Small-scale

0.445

High

672015

MSH3
DNA mismatch repair protein MSH3

1

0

High-throughput

0.426

High

803484

NEM1
Nuclear envelope morphology protein 1

1

0

High-throughput

0.282

High

817140

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.269

Low

817124

CCC1
Protein CCC1

1

0

High-throughput

0.265

Low

812331

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

817131

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

817169

CENPO
Inner kinetochore subunit MCM21

1

0

High-throughput

0.238

Low

810812

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025