HitPredict

Interactor 1: ARF4 (P18085)
ADP-ribosylation factor 4
Gene: ARF4

Interactor 2: AP4E1 (Q9UPM8)
AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin)
Gene: AP4E1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~Arf
Common GO terms	GO:0006886 - intracellular protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 180 Hs			1 1137
+	Hs
		913190 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP4E1_HUMAN (1-1137): 0: 1063: 100.00
+	Hs
		950744 ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00		AP4E1_HUMAN (1-1137): 0: 1063: 100.00
+	Hs
		897418 ARF3_HUMAN (1-180): 2.97e-67: 204: 78.89		AP4E1_HUMAN (1-1137): 0: 1063: 100.00
+	Hs
		950578 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		AP4E1_HUMAN (1-1137): 0: 1063: 100.00
+	Hs
		912839 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP2B1_HUMAN (59-902): 0: 636: 14.14
+	Hs
		212615 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP1G1_HUMAN (30-847): 0: 631: 20.96
+	Hs
		321520 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP2A1_HUMAN (25-913): 0: 623: 18.70
+	Hs
		912875 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP1B1_HUMAN (59-901): 0: 598: 13.84
+	Hs
		150201 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP3D1_HUMAN (32-1044): 0: 596: 17.13
+	Hs
		212618 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		AP1G1_HUMAN (30-847): 0: 631: 20.96
+	Hs
		150205 ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00		AP3D1_HUMAN (32-1044): 0: 596: 17.13
+	Hs
		150172 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		AP3D1_HUMAN (32-1044): 0: 596: 17.13
+	Hs
		950481 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		AP1B1_HUMAN (59-901): 0: 598: 13.84
+	Hs
		150198 ARF3_HUMAN (1-180): 2.97e-67: 204: 78.89		AP3D1_HUMAN (32-1044): 0: 596: 17.13
+	Hs
		150204 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		AP3D1_HUMAN (32-1044): 0: 596: 17.13
+	Dm
		778364 ARF4_DROME (1-180): 9.61e-69: 208: 84.44		Q24253_DROME (59-902): 0: 571: 13.78
+	Dm
		897433 ARF1_DROME (1-179): 6.66e-67: 203: 82.12		Q24253_DROME (59-902): 0: 571: 13.78
+	Dm
		778369 ARF4_DROME (1-180): 9.61e-69: 208: 84.44		Q7KVR8_DROME (28-616): 1.19e-172: 535: 24.96
+	Dm
		778362 ARF4_DROME (1-180): 9.61e-69: 208: 84.44		AP3D_DROME (32-590): 2.46e-150: 478: 22.96
+	Dm
		870249 ARF1_DROME (1-179): 6.66e-67: 203: 82.12		AP3D_DROME (32-590): 2.46e-150: 478: 22.96