HitPredict

Interactor 1: A2BDD9 (A2BDD9)
AMOT protein
Gene: AMOT

Interactor 2: LZTS1 (Q9Y250)
Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1)
Gene: LZTS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 676 Hs			1 596
+	Hs
		1119098 AMOT_HUMAN (1-676): 1.97e-48: 185: 99.56		LZTS1_HUMAN (1-596): 1.46e-59: 210: 100.00
+	Hs
		1119042 AMOT_HUMAN (1-676): 1.97e-48: 185: 99.56		LZTS2_HUMAN (1-596): 1.2e-37: 150: 34.66
+	Hs
		1119108 AMOT_HUMAN (1-676): 1.97e-48: 185: 99.56		MTCL1_HUMAN (8-570): 1.12e-25: 115: 11.74
+	Hs
		1118957 AMOT_HUMAN (1-676): 1.97e-48: 185: 99.56		CCD18_HUMAN (259-552): 2.97e-11: 68.8: 21.59
+	Hs
		165784 MYO5C_HUMAN (6-429): 2.33e-22: 104: 10.00		N4BP3_HUMAN (1-576): 8.13e-35: 140: 27.24
+	Hs
		1137917 MRCKB_HUMAN (1-465): 1.84e-19: 95.7: 11.25		MRCKA_HUMAN (329-595): 7.21e-19: 93.5: 18.28
+	Hs
		1137871 MRCKA_HUMAN (1-468): 3.15e-19: 94.9: 11.75		MRCKA_HUMAN (329-595): 7.21e-19: 93.5: 18.28
+	Rn
		222476 MRCKB_RAT (2-466): 4.37e-20: 97.6: 12.45		MRCKA_RAT (329-596): 2.89e-17: 88: 17.83
+	Rn
		222472 MRCKA_RAT (1-468): 1.46e-18: 93: 9.83		MRCKA_RAT (329-596): 2.89e-17: 88: 17.83
+	Hs
		1078828 ITSN1_HUMAN (3-501): 4.06e-13: 75.2: 11.35		ITSN1_HUMAN (1-580): 2.62e-20: 98.1: 12.58
+	Hs
		1268099 MYO5C_HUMAN (6-429): 2.33e-22: 104: 10.00		MY18A_HUMAN (240-536): 3.63e-11: 68.5: 12.58
+	Hs
		725035 MYO5C_HUMAN (6-429): 2.33e-22: 104: 10.00		MYH9_HUMAN (154-534): 4.65e-10: 64.9: 12.04
+	Hs
		1268126 MRCKB_HUMAN (1-465): 1.84e-19: 95.7: 11.25		MY18A_HUMAN (240-536): 3.63e-11: 68.5: 12.58
+	Hs
		1146002 MRCKB_HUMAN (1-465): 1.84e-19: 95.7: 11.25		CP135_HUMAN (242-539): 1.03e-10: 66.8: 20.19
+	Hs
		1137872 MRCKA_HUMAN (1-468): 3.15e-19: 94.9: 11.75		CP135_HUMAN (242-539): 1.03e-10: 66.8: 20.19
+	Rn
		1186812 MRCKB_RAT (2-466): 4.37e-20: 97.6: 12.45		MRCKB_RAT (170-510): 9.99e-09: 60.7: 11.40
+	Rn
		361106 MYH6_RAT (15-406): 3.2e-11: 69.1: 11.79		MYH6_RAT (194-595): 1.66e-11: 69.6: 10.89
+	Hs
		724687 MYH10_HUMAN (55-430): 4.96e-11: 68.3: 13.03		MYH9_HUMAN (154-534): 4.65e-10: 64.9: 12.04