HitPredict

Interactor 1: PTPRA (P18433)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)
Gene: PTPRA

Interactor 2: TPC2 (Q8NHX9)
Two pore channel protein 2 (Two pore calcium channel protein 2)
Gene: TPCN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 752
+	Hs
		617000 PTPRD_HUMAN (38-799): 0: 897: 40.50		TPC2_HUMAN (1-752): 1.92e-153: 466: 100.00
+	Hs
		577021 PTPRA_HUMAN (1-802): 0: 1040: 100.00		CAC1C_HUMAN (47-441): 4.33e-39: 158: 12.50
+	Hs
		1031981 PTPRS_HUMAN (5-799): 0: 925: 38.45		CAC1C_HUMAN (47-441): 4.33e-39: 158: 12.50
+	Hs
		616972 PTPRD_HUMAN (38-799): 0: 897: 40.50		CAC1C_HUMAN (47-441): 4.33e-39: 158: 12.50
+	Hs
		489959 PTPRF_HUMAN (4-799): 0: 894: 40.52		CAC1C_HUMAN (47-441): 4.33e-39: 158: 12.50
+	Hs
		1032019 PTPRS_HUMAN (5-799): 0: 925: 38.45		SCN2A_HUMAN (418-724): 5.94e-18: 91.1: 14.21
+	Hs
		617111 PTPRG_HUMAN (14-798): 0: 788: 29.12		CAC1C_HUMAN (47-441): 4.33e-39: 158: 12.50
+	Hs
		640246 PTN3_HUMAN (520-793): 1.24e-105: 347: 30.82		SCN5A_HUMAN (428-682): 9.3e-23: 106: 13.28
+	Hs
		1047187 PTPRU_HUMAN (221-508): 2.18e-61: 227: 27.85		CAC1C_HUMAN (47-441): 4.33e-39: 158: 12.50
+	Rn
		388054 PTPRZ_RAT (126-516): 8.2e-53: 201: 22.91		SCN1A_RAT (418-724): 6.72e-19: 94.2: 15.59