HitPredict

Interactor 1: PTPRA (P18433)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)
Gene: PTPRA

Interactor 2: LEG12 (Q96DT0)
Galectin-12 (Gal-12) (Galectin-related inhibitor of proliferation)
Gene: LGALS12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 336
+	Hs
		572277 PTPRA_HUMAN (1-802): 0: 1040: 100.00		LEG3_HUMAN (188-333): 3.97e-45: 156: 22.37
+	Hs
		577026 PTPRA_HUMAN (1-802): 0: 1040: 100.00		LEG9B_HUMAN (6-181): 1.44e-41: 149: 29.61
+	Hs
		119150 PTPRA_HUMAN (1-802): 0: 1040: 100.00		LEG9_HUMAN (6-181): 5.5e-41: 148: 29.61
+	Hs
		121103 PTPRA_HUMAN (1-802): 0: 1040: 100.00		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		449184 PTPRA_HUMAN (1-802): 0: 1040: 100.00		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		1069959 PTPRK_HUMAN (14-794): 0: 757: 32.41		LEG12_HUMAN (1-336): 6.96e-123: 358: 100.00
+	Hs
		449192 PTPRD_HUMAN (38-799): 0: 897: 40.50		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		572281 PTPRG_HUMAN (14-798): 0: 788: 29.12		LEG3_HUMAN (188-333): 3.97e-45: 156: 22.37
+	Hs
		119173 PTPRG_HUMAN (14-798): 0: 788: 29.12		LEG9_HUMAN (6-181): 5.5e-41: 148: 29.61
+	Hs
		121108 PTPRG_HUMAN (14-798): 0: 788: 29.12		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		572363 PTPRK_HUMAN (14-794): 0: 757: 32.41		LEG3_HUMAN (188-333): 3.97e-45: 156: 22.37
+	Hs
		449193 PTPRG_HUMAN (14-798): 0: 788: 29.12		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		119390 PTPRK_HUMAN (14-794): 0: 757: 32.41		LEG9_HUMAN (6-181): 5.5e-41: 148: 29.61
+	Hs
		814954 PTPRK_HUMAN (14-794): 0: 757: 32.41		LEG7_HUMAN (209-335): 8.76e-39: 135: 26.87
+	Hs
		121159 PTPRK_HUMAN (14-794): 0: 757: 32.41		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		449266 PTPRK_HUMAN (14-794): 0: 757: 32.41		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		572351 PTPRJ_HUMAN (516-797): 1.76e-118: 390: 38.87		LEG3_HUMAN (188-333): 3.97e-45: 156: 22.37
+	Hs
		119354 PTPRJ_HUMAN (516-797): 1.76e-118: 390: 38.87		LEG9_HUMAN (6-181): 5.5e-41: 148: 29.61
+	Hs
		121146 PTPRJ_HUMAN (516-797): 1.76e-118: 390: 38.87		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		449248 PTPRJ_HUMAN (516-797): 1.76e-118: 390: 38.87		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58