Protein: JEM1
DnaJ-like chaperone JEM1 (DnaJ-like protein of the ER membrane 1)

Gene: JEM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: P40358

Gene Ontology (top 5):
GO:0000742 - karyogamy involved in conjugation with cellular fusion
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0031965 - nuclear membrane
GO:0034975 - protein folding in endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

597157

BIP
Endoplasmic reticulum chaperone BiP

2

20

Small-scale

0.812

High

524135

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.618

High

545099

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.618

High

823261

JEM1
DnaJ-like chaperone JEM1

1

18

High-throughput

0.618

High

823264

EPS1
ER-retained PMA1-suppressing protein 1

1

20

High-throughput

0.575

High

823269

TOS3
Serine/threonine-protein kinase TOS3

1

2

High-throughput

0.514

High

738475

NUP2
Nucleoporin NUP2

1

4

High-throughput

0.445

High

795020

NU170
Nucleoporin NUP170

1

3

High-throughput

0.445

High

803571

RPN1
26S proteasome regulatory subunit RPN1

1

7

High-throughput

0.445

High

823275

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

High-throughput

0.445

High

823279

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

1

High-throughput

0.445

High

823286

UFD2
E4 ubiquitin-protein ligase UFD2

1

12

High-throughput

0.445

High

444541

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.437

High

707270

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

709797

BMH1
Protein BMH1

1

2

High-throughput

0.437

High

823285

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.437

High

823296

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

813406

PO152
Nucleoporin POM152

1

0

High-throughput

0.426

High

813628

NUP60
Nucleoporin NUP60

1

0

High-throughput

0.426

High

823284

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

823308

SEC39
Protein transport protein SEC39

1

0

High-throughput

0.426

High

459101

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.407

High

557601

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

9

High-throughput

0.407

High

574804

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

4

High-throughput

0.407

High

598871

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

4

High-throughput

0.407

High

599034

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

4

High-throughput

0.407

High

609063

SKI3
Superkiller protein 3

1

10

High-throughput

0.407

High

632684

DBP4
ATP-dependent RNA helicase HCA4

1

5

High-throughput

0.407

High

638726

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

3

High-throughput

0.407

High

647778

RFA1
Replication factor A protein 1

1

5

High-throughput

0.407

High

649499

UBA1
Ubiquitin-activating enzyme E1 1

1

2

High-throughput

0.407

High

677035

GID7
GID complex subunit 7

1

6

High-throughput

0.407

High

678600

IMG2
Large ribosomal subunit protein mL49

1

1

High-throughput

0.407

High

688750

RFA2
Replication factor A protein 2

1

3

High-throughput

0.407

High

699957

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

2

High-throughput

0.407

High

733586

P5CR
Pyrroline-5-carboxylate reductase

1

5

High-throughput

0.407

High

734861

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

1

High-throughput

0.407

High

737144

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

1

3

High-throughput

0.407

High

739657

SPT16
FACT complex subunit SPT16

1

3

High-throughput

0.407

High

746994

PREP
Presequence protease, mitochondrial

1

3

High-throughput

0.407

High

753243

MFT1
THO complex subunit MFT1

1

1

High-throughput

0.407

High

778849

AP1B1
AP-1 complex subunit beta-1

1

1

High-throughput

0.407

High

779064

EF1G2
Elongation factor 1-gamma 2

1

2

High-throughput

0.407

High

780608

CAB3
Coenzyme A biosynthesis protein 3

1

1

High-throughput

0.407

High

798144

ARPC1
Actin-related protein 2/3 complex subunit 1

1

11

High-throughput

0.407

High

803250

YLF2
Obg-like ATPase homolog

1

1

High-throughput

0.407

High

808816

SHC1
Protein SHC1

1

3

High-throughput

0.407

High

812858

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

4

High-throughput

0.407

High

818005

LSM4
LSM complex subunit LSM4

1

1

High-throughput

0.407

High

823262

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

3

High-throughput

0.407

High

823266

SA185
SIT4-associating protein SAP185

1

2

High-throughput

0.407

High

823267

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.407

High

823274

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.407

High

823277

PESC
Pescadillo homolog

1

3

High-throughput

0.407

High

823278

COPA
Coatomer subunit alpha

1

11

High-throughput

0.407

High

823280

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.407

High

823287

H3
Histone H3

1

7

High-throughput

0.407

High

823288

PURA
Adenylosuccinate synthetase

1

1

High-throughput

0.407

High

823289

NAM8
Protein NAM8

1

1

High-throughput

0.407

High

823290

NOP3
Serine/arginine

1

1

High-throughput

0.407

High

823292

CWC21
Pre-mRNA-splicing factor CWC21

1

1

High-throughput

0.407

High

823294

RRP5
rRNA biogenesis protein RRP5

1

3

High-throughput

0.407

High

823295

ELP1
Elongator complex protein 1

1

1

High-throughput

0.407

High

823297

FRA1
Putative Xaa-Pro aminopeptidase FRA1

1

1

High-throughput

0.407

High

823298

NOC3
Nucleolar complex-associated protein 3

1

3

High-throughput

0.407

High

823301

ARP8
Actin-like protein ARP8

1

2

High-throughput

0.407

High

823302

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

3

High-throughput

0.407

High

823303

PRP46
Pre-mRNA-splicing factor PRP46

1

10

High-throughput

0.407

High

823304

NSI1
RNA polymerase I termination factor

1

2

High-throughput

0.407

High

823305

NOP56
Nucleolar protein 56

1

3

High-throughput

0.407

High

823306

NOP58
Nucleolar protein 58

1

3

High-throughput

0.407

High

823272

MPS3
Spindle pole body assembly component MPS3

2

0

Small-scale

0.323

High

512088

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

557721

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.249

Low

823300

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

365634

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.232

Low

366715

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.232

Low

448388

RAD1
DNA repair protein RAD1

1

0

High-throughput

0.232

Low

482030

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.232

Low

555257

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.232

Low

605903

HPR1
THO complex subunit HPR1

1

0

High-throughput

0.232

Low

736657

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low

740802

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.232

Low

746284

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.232

Low

746770

PDC2
Protein PDC2

1

0

High-throughput

0.232

Low

747730

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.232

Low

763520

MAC1
Metal-binding activator 1

1

0

High-throughput

0.232

Low

791965

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.232

Low

814138

SAW1
Single-strand annealing weakened protein 1

1

0

High-throughput

0.232

Low

818456

LSM5
LSM complex subunit LSM5

1

0

High-throughput

0.232

Low

820458

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

1

0

High-throughput

0.232

Low

823263

YIF8
Putative uncharacterized protein YIL058W

1

0

High-throughput

0.232

Low

823265

EGH1
Ergosteryl-beta-glucosidase

1

0

High-throughput

0.232

Low

823268

BLM10
Proteasome activator BLM10

1

0

High-throughput

0.232

Low

823270

MTHR1
Methylenetetrahydrofolate reductase 1

1

0

High-throughput

0.232

Low

823271

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.232

Low

823273

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.232

Low

823276

ORC5
Origin recognition complex subunit 5

1

0

High-throughput

0.232

Low

823281

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.232

Low

823282

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.232

Low

823283

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.232

Low

823291

SGF11
SAGA complex subunit SGF11

1

0

High-throughput

0.232

Low

823293

RAD33
DNA repair protein RAD33

1

0

High-throughput

0.232

Low

823299

TMC1
AN1-type zinc finger protein TMC1

1

0

High-throughput

0.232

Low

823307

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025