HitPredict

Interactor 1: AP2A2 (P18484)
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene: AP2A2

Interactor 2: Q3MUI1 (Q3MUI1)
Numb
Gene: Numb

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17022975
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 938 Rn			1 592
+	Rn
		1109842 Q66HM2_RAT (1-938): 0: 890: 99.57		Q3MUI1_RAT (1-592): 2.71e-94: 302: 100.00
+	Hs
		302120 AP2A2_HUMAN (1-938): 0: 872: 96.06		NUMB_HUMAN (1-592): 7.55e-83: 274: 84.20
+	Hs
		321513 AP2A1_HUMAN (1-938): 0: 834: 78.37		NUMB_HUMAN (1-592): 7.55e-83: 274: 84.20
+	Mm
		567529 AP2A2_MOUSE (1-938): 0: 895: 99.79		ANS1B_MOUSE (7-216): 1.31e-40: 160: 20.52
+	Rn
		1144064 Q66HM2_RAT (1-938): 0: 890: 99.57		SYNJ1_RAT (86-587): 5.66e-38: 152: 11.59
+	Hs
		302137 AP2A2_HUMAN (1-938): 0: 872: 96.06		DAB2_HUMAN (31-545): 8.67e-39: 154: 14.50
+	Hs
		321528 AP2A1_HUMAN (1-938): 0: 834: 78.37		DAB2_HUMAN (31-545): 8.67e-39: 154: 14.50
+	Dm
		561275 AP2A_DROME (3-938): 0: 822: 69.47		NUMB_DROME (16-584): 4.01e-42: 161: 34.62
+	Ce
		283751 Q22601_CAEEL (3-938): 0: 788: 64.12		CED6_CAEEL (23-409): 4.95e-38: 148: 17.04
+	Rn
		923852 AP2B1_RAT (36-933): 0: 628: 16.58		Q3MUI1_RAT (1-592): 2.71e-94: 302: 100.00
+	Ce
		60774 Q22601_CAEEL (3-938): 0: 788: 64.12		A5JYR4_CAEEL (10-336): 7.8e-34: 136: 14.50
+	Hs
		833587 AP1B1_HUMAN (36-935): 0: 631: 16.99		NUMB_HUMAN (1-592): 7.55e-83: 274: 84.20
+	Hs
		833572 AP2B1_HUMAN (36-933): 0: 628: 16.58		NUMB_HUMAN (1-592): 7.55e-83: 274: 84.20
+	Hs
		203194 AP2A1_HUMAN (1-938): 0: 834: 78.37		SYNJ1_HUMAN (330-589): 6.61e-09: 61.3: 9.96
+	Hs
		1014028 AP1B1_HUMAN (36-935): 0: 631: 16.99		ARH_HUMAN (7-271): 1.39e-51: 181: 21.77
+	Hs
		925893 AP2B1_HUMAN (36-933): 0: 628: 16.58		ARH_HUMAN (7-271): 1.39e-51: 181: 21.77
+	Hs
		925851 AP2B1_HUMAN (36-933): 0: 628: 16.58		DAB2_HUMAN (31-545): 8.67e-39: 154: 14.50
+	Hs
		253551 AP2B1_HUMAN (36-933): 0: 628: 16.58		CAPON_HUMAN (26-262): 2.35e-32: 132: 16.91
+	Hs
		203223 AP1B1_HUMAN (36-935): 0: 631: 16.99		SYNJ1_HUMAN (330-589): 6.61e-09: 61.3: 9.96
+	Hs
		203219 AP2B1_HUMAN (36-933): 0: 628: 16.58		SYNJ1_HUMAN (330-589): 6.61e-09: 61.3: 9.96