HitPredict

Interactor 1: SYB (P18489)
Synaptobrevin
Gene: SYB

Interactor 2: Q9VVX6 (Q9VVX6)
Blocked early in transport 1, isoform A (Blocked early in transport 1, isoform B) (RH40423p)
Gene: Bet1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0005484 - SNAP receptor activity GO:0016192 - vesicle-mediated transport GO:0019905 - syntaxin binding GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Dm			1 117
+	Dm
		577224 SYB_DROME (1-152): 8.51e-56: 173: 100.00		Q7JRF1_DROME (17-116): 8.56e-23: 92: 17.00
+	Hs
		169333 SC22B_HUMAN (3-131): 1.41e-37: 129: 20.61		BET1_HUMAN (10-117): 1.07e-36: 122: 39.82
+	Dm
		1178137 Q7JYX5_DROME (23-127): 1.45e-36: 126: 16.82		Q9VVX6_DROME (1-117): 3.49e-37: 123: 100.00
+	Dm
		115845 M9PGI6_DROME (3-128): 1.23e-31: 113: 16.67		Q9VVX6_DROME (1-117): 3.49e-37: 123: 100.00
+	Hs
		169416 VAMP7_HUMAN (23-112): 1.58e-29: 108: 26.09		BET1_HUMAN (10-117): 1.07e-36: 122: 39.82
+	Rn
		1125559 YKT6_RAT (1-101): 3.14e-29: 107: 21.78		BET1_RAT (7-117): 1.18e-36: 122: 36.94
+	Hs
		169321 YKT6_HUMAN (1-101): 4.73e-29: 107: 21.78		BET1_HUMAN (10-117): 1.07e-36: 122: 39.82
+	Mm
		193165 YKT6_MOUSE (1-101): 3.02e-28: 104: 20.79		BET1_MOUSE (7-117): 4.91e-36: 120: 36.94
+	Hs
		263378 SC22B_HUMAN (3-131): 1.41e-37: 129: 20.61		BET1L_HUMAN (20-114): 3.42e-24: 90.5: 31.25
+	Hs
		235130 SC22B_HUMAN (3-131): 1.41e-37: 129: 20.61		STX10_HUMAN (18-100): 5.57e-21: 85.9: 20.48
+	Hs
		212690 SC22B_HUMAN (3-131): 1.41e-37: 129: 20.61		STX6_HUMAN (8-100): 1.4e-19: 82.4: 22.58
+	Sc
		605819 SEC22_YEAST (3-129): 2.65e-33: 118: 19.38		BET1_YEAST (17-114): 7.22e-25: 93.2: 21.43
+	Sc
		605860 SEC22_YEAST (3-129): 2.65e-33: 118: 19.38		SFT1_YEAST (19-116): 2.55e-21: 82.8: 19.39
+	Rn
		192329 YKT6_RAT (1-101): 3.14e-29: 107: 21.78		BET1L_RAT (19-114): 1.7e-24: 91.3: 29.90
+	Hs
		180946 YKT6_HUMAN (1-101): 4.73e-29: 107: 21.78		BET1L_HUMAN (20-114): 3.42e-24: 90.5: 31.25
+	Rn
		1144363 VAMP1_RAT (18-120): 1.79e-31: 110: 56.31		STX6_RAT (8-101): 2.99e-20: 83.9: 22.34
+	Hs
		212772 VAMP7_HUMAN (23-112): 1.58e-29: 108: 26.09		STX6_HUMAN (8-100): 1.4e-19: 82.4: 22.58
+	Hs
		235129 VAMP4_HUMAN (30-115): 8.22e-29: 104: 30.23		STX10_HUMAN (18-100): 5.57e-21: 85.9: 20.48
+	Hs
		180766 YKT6_HUMAN (1-101): 4.73e-29: 107: 21.78		STX6_HUMAN (8-100): 1.4e-19: 82.4: 22.58
+	Hs
		212689 VAMP4_HUMAN (30-115): 8.22e-29: 104: 30.23		STX6_HUMAN (8-100): 1.4e-19: 82.4: 22.58