Protein: HPH2
Protein HPH2 (Functionally related to TCP1 protein 2) (High pH protein 2)

Gene: HPH2, FRT2
Organism: Saccharomyces cerevisiae S288C
Interactions: 57
UniProt ID: P39734

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0031204 - post-translational protein targeting to membrane, translocation
GO:0071469 - cellular response to alkaline pH
GO:0071472 - cellular response to salt stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

364547

CDK1
Cyclin-dependent kinase 1

2

0

High-throughput

0.603

High

656473

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

735498

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.501

High

814129

ADY3
Accumulates dyads protein 3

1

1

High-throughput

0.494

High

814132

ERP3
Protein ERP3

1

1

High-throughput

0.481

High

577135

SEC63
Protein translocation protein SEC63

1

1

Small-scale

0.479

High

641376

SEC62
Translocation protein SEC62

1

1

Small-scale

0.479

High

748402

SC61A
Protein transport protein SEC61

1

1

Small-scale

0.479

High

754397

SEC66
Translocation protein SEC66

1

1

Small-scale

0.479

High

814117

SEC72
Translocation protein SEC72

1

1

Small-scale

0.479

High

814135

HPH1
Protein HPH1

1

1

Small-scale

0.479

High

579426

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.470

High

642391

MCK1
Protein kinase MCK1

1

1

High-throughput

0.457

High

656780

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.457

High

666186

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

1

High-throughput

0.457

High

740579

IME2
Meiosis induction protein kinase IME2/SME1

1

2

High-throughput

0.457

High

778895

NNK1
Nitrogen network kinase 1

1

1

High-throughput

0.457

High

800607

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

1

High-throughput

0.457

High

801831

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.457

High

814123

CLA4
Serine/threonine-protein kinase CLA4

1

1

High-throughput

0.457

High

814126

STE20
Serine/threonine-protein kinase STE20

1

1

High-throughput

0.457

High

814133

SKS1
Serine/threonine-protein kinase SKS1

1

1

High-throughput

0.457

High

646040

KIN3
Serine/threonine-protein kinase KIN3

1

2

High-throughput

0.439

High

779756

DYHC
Dynein heavy chain, cytoplasmic

1

1

High-throughput

0.439

High

780879

STB6
Protein STB6

1

3

High-throughput

0.439

High

809182

END3
Actin cytoskeleton-regulatory complex protein END3

1

1

High-throughput

0.439

High

814119

FMP32
Protein FMP32, mitochondrial

1

1

High-throughput

0.439

High

814120

STB2
Protein STB2

1

3

High-throughput

0.439

High

814128

HDA2
HDA1 complex subunit 2

1

1

High-throughput

0.439

High

814122

GPI14
GPI mannosyltransferase 1

1

0

High-throughput

0.438

High

524015

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.437

High

526749

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.437

High

506370

NFT1
ABC transporter NFT1

1

0

High-throughput

0.282

High

603055

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.265

Low

574684

KSS1
Mitogen-activated protein kinase KSS1

1

0

High-throughput

0.261

Low

646412

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.261

Low

672191

KIN82
Serine/threonine-protein kinase KIN82

1

0

High-throughput

0.261

Low

692353

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

748846

SWE1
Mitosis inhibitor protein kinase SWE1

1

0

High-throughput

0.261

Low

814118

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.261

Low

814124

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

814131

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.261

Low

506393

YK104
Putative uncharacterized protein YKR104W

1

0

High-throughput

0.251

Low

557714

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.251

Low

602047

KAR3
Kinesin-like protein KAR3

1

0

High-throughput

0.251

Low

749673

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

753085

NIP80
Protein NIP100

1

0

High-throughput

0.251

Low

796308

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

806279

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.251

Low

813797

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

814121

MDV1
Mitochondrial division protein 1

1

0

High-throughput

0.251

Low

814127

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.251

Low

814130

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.251

Low

814134

YI002
Uncharacterized protein YIL002W-A

1

0

High-throughput

0.251

Low

793077

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.249

Low

814125

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

Small-scale

0.249

Low

743460

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025