HitPredict

Interactor 1: ATF3 (P18847)
Cyclic AMP-dependent transcription factor ATF-3 (cAMP-dependent transcription factor ATF-3) (Activating transcription factor 3)
Gene: ATF3

Interactor 2: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	16169070
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 181 Hs			1 806
+	Hs
		566723 JUNB_HUMAN (27-155): 8.92e-26: 102: 18.46		FGFR3_HUMAN (10-806): 0: 819: 100.00
+	Hs
		401422 JUN_HUMAN (10-155): 1.25e-23: 96.9: 19.73		FGFR3_HUMAN (10-806): 0: 819: 100.00
+	Hs
		548223 FOSL1_HUMAN (42-169): 1.11e-22: 93.4: 26.76		FGFR3_HUMAN (10-806): 0: 819: 100.00
+	Hs
		548283 FOSL2_HUMAN (54-164): 3.35e-22: 92.9: 37.84		FGFR3_HUMAN (10-806): 0: 819: 100.00
+	Hs
		609304 BATF_HUMAN (82-165): 1.89e-20: 83.7: 38.10		FGFR3_HUMAN (10-806): 0: 819: 100.00
+	Hs
		401697 JUN_HUMAN (10-155): 1.25e-23: 96.9: 19.73		EPHB4_HUMAN (1-786): 8.14e-179: 541: 17.79
+	Mm
		404107 JUN_MOUSE (10-155): 1.94e-23: 96.5: 19.46		CSF1R_MOUSE (5-764): 1.87e-167: 511: 27.49