Interactor 1: ATF4 (P18848)
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (Tax-responsive enhancer element-binding protein 67) (TaxREB67)
Gene: ATF4

Interactor 2: GPS2 (Q13227)
G protein pathway suppressor 2 (GPS-2)
Gene: GPS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.726

The method score is based on:

Property Details
Experiments 25416956, 16189514, 29892012, 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 351
Hs

1 327
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024