HitPredict

Interactor 1: GNAO (P18872)
Guanine nucleotide-binding protein G(o) subunit alpha
Gene: Gnao1

Interactor 2: GBG2 (P63213)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (G gamma-I)
Gene: Gng2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8550614
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005834 - heterotrimeric G-protein complex GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Mm			1 71
+	Hs
		450995 GNAO_HUMAN (1-354): 5.61e-177: 496: 98.02		GBG2_HUMAN (1-71): 3.57e-29: 100: 100.00
+	Hs
		451002 GNAO_HUMAN (1-354): 5.61e-177: 496: 98.02		GBG3_HUMAN (4-71): 3.14e-27: 95.1: 79.41
+	Hs
		451049 GNAO_HUMAN (1-354): 5.61e-177: 496: 98.02		GBG8_HUMAN (3-71): 8.51e-26: 91.7: 71.01
+	Hs
		391364 GNAI2_HUMAN (1-354): 8.35e-172: 483: 68.45		GBG2_HUMAN (1-71): 3.57e-29: 100: 100.00
+	Hs
		887099 GNAI1_HUMAN (1-354): 4.79e-171: 481: 71.83		GBG2_HUMAN (1-71): 3.57e-29: 100: 100.00
+	Hs
		391359 GNAI2_HUMAN (1-354): 8.35e-172: 483: 68.45		GBG4_HUMAN (1-71): 6.54e-28: 97: 77.47
+	Hs
		391377 GNAI2_HUMAN (1-354): 8.35e-172: 483: 68.45		GBG3_HUMAN (4-71): 3.14e-27: 95.1: 79.41
+	Hs
		450990 GNAO_HUMAN (1-354): 5.61e-177: 496: 98.02		GBG10_HUMAN (4-71): 4.34e-22: 82: 52.94
+	Hs
		837675 GNAI1_HUMAN (1-354): 4.79e-171: 481: 71.83		GBG4_HUMAN (1-71): 6.54e-28: 97: 77.47
+	Hs
		926667 GNAI1_HUMAN (1-354): 4.79e-171: 481: 71.83		GBG3_HUMAN (4-71): 3.14e-27: 95.1: 79.41
+	Hs
		391482 GNAI2_HUMAN (1-354): 8.35e-172: 483: 68.45		GBG8_HUMAN (3-71): 8.51e-26: 91.7: 71.01
+	Hs
		229233 GNAI2_HUMAN (1-354): 8.35e-172: 483: 68.45		GBG7_HUMAN (4-71): 4.42e-25: 89.7: 70.59
+	Hs
		926724 GNAI1_HUMAN (1-354): 4.79e-171: 481: 71.83		GBG8_HUMAN (3-71): 8.51e-26: 91.7: 71.01
+	Hs
		229239 GNAI1_HUMAN (1-354): 4.79e-171: 481: 71.83		GBG7_HUMAN (4-71): 4.42e-25: 89.7: 70.59
+	Hs
		444694 GNAI3_HUMAN (1-354): 1.13e-167: 473: 70.70		GBG4_HUMAN (1-71): 6.54e-28: 97: 77.47
+	Hs
		391360 GNAI2_HUMAN (1-354): 8.35e-172: 483: 68.45		GBG10_HUMAN (4-71): 4.34e-22: 82: 52.94
+	Hs
		837689 GNAI1_HUMAN (1-354): 4.79e-171: 481: 71.83		GBG10_HUMAN (4-71): 4.34e-22: 82: 52.94
+	Hs
		229234 GNAI3_HUMAN (1-354): 1.13e-167: 473: 70.70		GBG7_HUMAN (4-71): 4.42e-25: 89.7: 70.59
+	Hs
		391378 GNAI2_HUMAN (1-354): 8.35e-172: 483: 68.45		GBG5_HUMAN (4-71): 4.11e-21: 79.7: 48.53
+	Hs
		926668 GNAI1_HUMAN (1-354): 4.79e-171: 481: 71.83		GBG5_HUMAN (4-71): 4.11e-21: 79.7: 48.53