Interactor 1: XRCC1 (P18887)
DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)
Gene: XRCC1

Interactor 2: DNLI3 (P49916)
DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)
Gene: LIG3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.90 0.929

The method score is based on:

Property Details
Experiments 11352725, 33961781, 26496610, 11163244, 17353931, 29668892, 11909950, 8264637, 9136882, 9705932, 24981860, 34111398, 20227374
Identification Methods pull down, affinity chromatography technology, two hybrid, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT_2~LIG3_BRCT
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024