HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: UBC7 (Q02159)
Ubiquitin-conjugating enzyme E2 7 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 7) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC7

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 165
+	Hs
		468233 HS90B_HUMAN (5-705): 0: 1016: 61.15		UB2D3_HUMAN (4-164): 1.41e-71: 213: 36.03
+	Sc
		578769 HSC82_YEAST (1-705): 0: 971: 100.00		UBC4_YEAST (1-163): 6.7e-72: 214: 35.58
+	Sc
		392159 HSP82_YEAST (1-705): 0: 963: 95.63		UBC4_YEAST (1-163): 6.7e-72: 214: 35.58
+	Sc
		393195 HSP82_YEAST (1-705): 0: 963: 95.63		UBC7_YEAST (1-165): 2.17e-71: 213: 100.00
+	Hs
		468174 HS90B_HUMAN (5-705): 0: 1016: 61.15		UB2R1_HUMAN (4-145): 1.59e-40: 137: 49.30
+	Hs
		461268 HS90A_HUMAN (4-705): 0: 1007: 60.67		UB2R1_HUMAN (4-145): 1.59e-40: 137: 49.30
+	Sc
		574766 HSC82_YEAST (1-705): 0: 971: 100.00		UBC3_YEAST (4-162): 1.54e-35: 126: 41.36