HitPredict

Interactor 1: K2C4 (P19013)
Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Type-II keratin Kb4)
Gene: KRT4

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 520 Hs			1 440
+	Hs
		409063 K2C8_HUMAN (109-484): 5.4e-161: 467: 62.50		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036707 K2C73_HUMAN (2-453): 6.11e-100: 313: 63.74		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		319900 K2C1B_HUMAN (47-468): 4.52e-166: 484: 61.86		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		409074 K2C8_HUMAN (109-484): 5.4e-161: 467: 62.50		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Hs
		319741 K22E_HUMAN (109-490): 3.71e-151: 448: 65.71		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		319691 K2C6B_HUMAN (1-469): 3.93e-79: 259: 63.03		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		319759 K2C6C_HUMAN (1-469): 8.67e-79: 258: 62.63		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50