Protein: RSC3
Chromatin structure-remodeling complex protein RSC3 (Remodel the structure of chromatin complex subunit 3)

Gene: RSC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 103
UniProt ID: Q06639

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006337 - nucleosome disassembly
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

804008

RSC30
Chromatin structure-remodeling complex protein RSC30

5

1

Small-scale

0.925

High

1056351

RSC3
Chromatin structure-remodeling complex protein RSC3

2

1

High-throughput

0.759

High

1055383

RSC2
Chromatin structure-remodeling complex subunit RSC2

13

9

Small-scale

0.759

High

743144

STH1
Nuclear protein STH1/NPS1

11

2

Small-scale

0.756

High

745620

RSC7
Chromatin structure-remodeling complex subunit RSC7

6

1

Small-scale

0.736

High

850585

RSC8
Chromatin structure-remodeling complex protein RSC8

6

1

Small-scale

0.736

High

1041006

RSC9
Chromatin structure-remodeling complex subunit RSC9

6

1

Small-scale

0.732

High

1056352

RSC58
Chromatin structure-remodeling complex protein RSC58

6

1

High-throughput

0.732

High

1035338

RSC4
Chromatin structure-remodeling complex subunit RSC4

6

8

High-throughput

0.730

High

678349

RSC6
Chromatin structure-remodeling complex protein RSC6

5

1

High-throughput

0.718

High

1050599

ARP9
Actin-like protein ARP9

5

1

High-throughput

0.718

High

1056359

ARP7
Actin-related protein 7

5

1

High-throughput

0.718

High

1054038

SFH1
Chromatin structure-remodeling complex subunit SFH1

5

1

Small-scale

0.716

High

382370

H4
Histone H4

5

1

Small-scale

0.712

High

918529

RSC1
Chromatin structure-remodeling complex subunit RSC1

5

10

Small-scale

0.709

High

419886

H2A2
Histone H2A.2

4

2

High-throughput

0.683

High

823050

ATAD2
ATPase histone chaperone YTA7

4

2

Small-scale

0.672

High

919695

RT102
Regulator of Ty1 transposition protein 102

3

1

High-throughput

0.667

High

381280

H2B1
Histone H2B.1

3

3

High-throughput

0.650

High

1056363

HTL1
High temperature lethal protein 1

3

1

Small-scale

0.650

High

527784

HSP72
Heat shock protein SSA2

3

2

High-throughput

0.643

High

963741

H3
Histone H3

3

1

Small-scale

0.641

High

742485

HSP7F
Heat shock protein homolog SSE1

2

3

High-throughput

0.628

High

734480

BTAF1
TATA-binding protein-associated factor MOT1

2

4

Small-scale

0.611

High

1056356

SCC1
Sister chromatid cohesion protein 1

2

1

Small-scale

0.611

High

525275

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.601

High

638821

REB1
DNA-binding protein REB1

2

0

High-throughput

0.595

High

764014

SPT10
Protein SPT10

2

1

High-throughput

0.571

High

877590

RFX1
RFX-like DNA-binding protein RFX1

2

0

High-throughput

0.563

High

546422

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

819900

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

419517

H2A1
Histone H2A.1

1

2

High-throughput

0.536

High

1036962

ABF2
ARS-binding factor 2, mitochondrial

1

3

High-throughput

0.536

High

1044592

HMO1
High mobility group protein 1

1

3

High-throughput

0.536

High

580128

HSC82
ATP-dependent molecular chaperone HSC82

2

2

High-throughput

0.533

High

794227

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.513

High

805224

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

0

High-throughput

0.513

High

1056358

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.513

High

737952

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.493

High

727342

HS104
Heat shock protein 104

1

0

High-throughput

0.479

High

381645

H2B2
Histone H2B.2

1

3

High-throughput

0.479

High

449015

TOP2
DNA topoisomerase 2

1

1

High-throughput

0.479

High

739788

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.479

High

748065

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

777125

BDF1
Bromodomain-containing factor 1

1

4

High-throughput

0.479

High

796040

LDB7
Chromatin structure-remodeling complex protein RSC14

1

1

High-throughput

0.479

High

826867

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

1044472

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

1056353

SGO1
Shugoshin

1

1

High-throughput

0.479

High

1056360

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

1056354

NAT5
N-alpha-acetyltransferase NAT5

1

1

High-throughput

0.470

High

448338

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

561538

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

594587

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

647233

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

647845

RFA1
Replication factor A protein 1

1

0

Small-scale

0.458

High

708291

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735183

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

745889

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

764160

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

818393

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

0

High-throughput

0.458

High

826406

MPH1
ATP-dependent DNA helicase MPH1

1

0

High-throughput

0.458

High

932236

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

1044773

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1056357

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

393394

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

448228

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.445

High

489005

SWI6
Regulatory protein SWI6

1

2

High-throughput

0.445

High

547831

NHP6A
Non-histone chromosomal protein 6A

1

1

High-throughput

0.445

High

671562

SWI4
Regulatory protein SWI4

1

2

High-throughput

0.445

High

736737

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.445

High

752992

IXR1
Intrastrand cross-link recognition protein

1

3

High-throughput

0.445

High

781810

SET3
SET domain-containing protein 3

1

1

High-throughput

0.445

High

820444

RT106
Histone chaperone RTT106

1

1

High-throughput

0.445

High

858477

TAF1
Transcription initiation factor TFIID subunit 1

1

1

High-throughput

0.445

High

1040029

HOS3
Histone deacetylase HOS3

1

1

High-throughput

0.445

High

1056361

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.445

High

1056362

H2AZ
Histone H2A.Z

1

4

High-throughput

0.445

High

805014

IPI1
Pre-rRNA-processing protein IPI1

1

0

High-throughput

0.438

High

548803

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.426

High

645649

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.426

High

650022

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

754251

MSN4
Zinc finger protein MSN4

1

0

High-throughput

0.426

High

1044154

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.426

High

1046940

POB3
FACT complex subunit POB3

1

0

High-throughput

0.426

High

1051135

SWR1
Helicase SWR1

1

0

High-throughput

0.426

High

587338

ABP1
Actin-binding protein

1

0

High-throughput

0.282

High

639074

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.279

Low

925322

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.279

Low

456550

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

0

High-throughput

0.269

Low

557636

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

0

High-throughput

0.269

Low

918466

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.269

Low

1056355

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.249

Low

394933

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

427456

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

453810

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

592521

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

736602

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.232

Low

747596

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low

755179

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.232

Low

836913

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

863759

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025