HitPredict

Interactor 1: CADH2 (P19022)
Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)
Gene: CDH2

Interactor 2: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20432435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 906 Hs			1 913
+	Hs
		580239 CADH2_HUMAN (1-906): 0: 998: 100.00		DDR2_HUMAN (20-905): 0: 843: 51.46
+	Hs
		521890 CADH1_HUMAN (26-906): 0: 764: 45.71		DDR1_HUMAN (1-913): 0: 911: 100.00
+	Hs
		521969 CADH1_HUMAN (26-906): 0: 764: 45.71		DDR2_HUMAN (20-905): 0: 843: 51.46
+	Hs
		1055828 DSC3_HUMAN (5-899): 0: 700: 30.32		DDR2_HUMAN (20-905): 0: 843: 51.46
+	Hs
		507842 CADH2_HUMAN (1-906): 0: 998: 100.00		FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52
+	Hs
		580237 CADH2_HUMAN (1-906): 0: 998: 100.00		NTRK3_HUMAN (607-905): 4.06e-67: 242: 43.63
+	Hs
		384238 CADH2_HUMAN (1-906): 0: 998: 100.00		NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27
+	Hs
		435531 CADH2_HUMAN (1-906): 0: 998: 100.00		IGF1R_HUMAN (600-908): 4.51e-51: 197: 37.22
+	Hs
		521694 CADH1_HUMAN (26-906): 0: 764: 45.71		SRC_HUMAN (361-912): 1.28e-125: 391: 23.60
+	Hs
		507817 CADH1_HUMAN (26-906): 0: 764: 45.71		FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52
+	Hs
		433230 CADH1_HUMAN (26-906): 0: 764: 45.71		YES_HUMAN (563-907): 1.25e-105: 339: 31.59
+	Hs
		508000 DSC3_HUMAN (5-899): 0: 700: 30.32		FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52
+	Hs
		971016 DSC2_HUMAN (42-899): 0: 710: 30.46		NTRK2_HUMAN (604-906): 1.75e-104: 345: 43.89
+	Hs
		433353 DSC3_HUMAN (5-899): 0: 700: 30.32		YES_HUMAN (563-907): 1.25e-105: 339: 31.59
+	Hs
		384675 DSC2_HUMAN (42-899): 0: 710: 30.46		NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27
+	Hs
		1055826 DSC3_HUMAN (5-899): 0: 700: 30.32		NTRK3_HUMAN (607-905): 4.06e-67: 242: 43.63
+	Hs
		411386 DSC3_HUMAN (5-899): 0: 700: 30.32		INSR_HUMAN (600-908): 7.71e-53: 202: 37.42
+	Hs
		435643 DSC3_HUMAN (5-899): 0: 700: 30.32		IGF1R_HUMAN (600-908): 4.51e-51: 197: 37.22
+	Hs
		537741 DSC3_HUMAN (5-899): 0: 700: 30.32		INSRR_HUMAN (600-908): 2.79e-50: 194: 38.71
+	Hs
		435534 CADH3_HUMAN (6-906): 0: 675: 41.24		IGF1R_HUMAN (600-908): 4.51e-51: 197: 37.22