Protein: YSH1
Endoribonuclease YSH1 (EC 3.1.27.-) (Yeast 73 kDa homolog 1) (mRNA 3'-end-processing protein YSH1)

Gene: YSH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: Q06224

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004521 - RNA endonuclease activity
GO:0004534 - 5'-3' RNA exonuclease activity
GO:0005634 - nucleus
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

776498

MPE1
Protein MPE1

10

3

Small-scale

0.977

High

1054427

CFT2
Cleavage factor two protein 2

6

14

Small-scale

0.949

High

1030138

PTA1
Pre-tRNA-processing protein PTA1

12

8

Small-scale

0.757

High

843179

PFS2
Polyadenylation factor subunit 2

7

11

Small-scale

0.750

High

853590

FIP1
Pre-mRNA polyadenylation factor FIP1

8

4

Small-scale

0.747

High

1053586

YTH1
mRNA 3'-end-processing protein YTH1

6

9

Small-scale

0.736

High

743292

PP12
Serine/threonine-protein phosphatase PP1-2

6

6

Small-scale

0.733

High

837287

REF2
RNA end formation protein 2

6

2

Small-scale

0.732

High

712940

PAP
Poly(A) polymerase

6

8

Small-scale

0.732

High

781159

SWD2
COMPASS component SWD2

6

8

Small-scale

0.732

High

1054424

CFT1
Protein CFT1

5

8

Small-scale

0.714

High

811237

PCF11
Protein PCF11

5

3

Small-scale

0.712

High

921029

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

5

5

Small-scale

0.709

High

1054426

CLP1
mRNA cleavage and polyadenylation factor CLP1

3

3

Small-scale

0.680

High

814989

PTI1
Protein PTI1

3

2

Small-scale

0.650

High

632744

DBP4
ATP-dependent RNA helicase HCA4

2

2

High-throughput

0.621

High

671429

RNA14
mRNA 3'-end-processing protein RNA14

2

3

High-throughput

0.621

High

751906

TFC4
Transcription factor tau 131 kDa subunit

2

1

Small-scale

0.595

High

393366

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.571

High

525222

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.552

High

546361

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

1042376

GCN5
Histone acetyltransferase GCN5

1

8

High-throughput

0.536

High

656628

KC11
Casein kinase I homolog 1

1

1

Small-scale

0.501

High

866269

YJ9I
Uncharacterized protein YJR141W

1

0

Small-scale

0.480

High

594579

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

655642

TAF2
Transcription initiation factor TFIID subunit 2

1

1

High-throughput

0.479

High

671455

RNA15
mRNA 3'-end-processing protein RNA15

1

11

Small-scale

0.479

High

708242

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

741127

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

3

High-throughput

0.479

High

858360

SAC3
Nuclear mRNA export protein SAC3

1

1

High-throughput

0.479

High

1044761

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

1054428

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

1054429

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.479

High

1054423

CORO
Coronin-like protein

1

3

High-throughput

0.470

High

748055

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

742448

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

403661

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.426

High

1035107

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.417

High

592513

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

826494

DJP1
DnaJ-like protein 1

1

1

High-throughput

0.407

High

1054425

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.407

High

820360

YNU8
Uncharacterized protein YNL208W

1

0

High-throughput

0.269

Low

824556

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low

863747

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025