HitPredict

Interactor 1: CDC42 (P19073)
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)
Gene: CDC42

Interactor 2: STE20 (Q03497)
Serine/threonine-protein kinase STE20 (EC 2.7.11.1)
Gene: STE20

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 7651520, 9003780, 11940652, 11489916, 11359919, 11113198, 7597098, 11046150, 10358031, 15108020, 17189484, 19955214, 7565673, 12586692, 12455995, 10411908, 15743816, 17914055, 20410294, 20171953 and 1 others

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Identification Methods two hybrid, affinity chromatography technology, enzymatic study, pull down, miniaturized immunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~Ras, Pkinase~Ras
Common GO terms GO:0000131 - incipient cellular bud site
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001403 - invasive growth in response to glucose limitation
GO:0005886 - plasma membrane
GO:0007096 - regulation of exit from mitosis
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Sc

1 939
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024