Protein: NOP14
Nucleolar complex protein 14 (U three protein 2) (U3 small nucleolar RNA-associated protein 2) (U3 snoRNA-associated protein 2)

Gene: NOP14
Organism: Saccharomyces cerevisiae S288C
Interactions: 156
UniProt ID: Q99207

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1055544

NOC4
Nucleolar complex protein 4

12

2

Small-scale

0.759

High

798369

ENP1
Essential nuclear protein 1

10

1

Small-scale

0.754

High

1046112

DHR1
Probable ATP-dependent RNA helicase DHR1

8

2

Small-scale

0.747

High

1054566

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

5

1

Small-scale

0.727

High

865204

MPP10
U3 small nucleolar RNA-associated protein MPP10

5

1

Small-scale

0.723

High

677650

KRR1
KRR1 small subunit processome component

5

1

High-throughput

0.716

High

1085004

NOP58
Nucleolar protein 58

5

2

Small-scale

0.714

High

918869

UTP22
U3 small nucleolar RNA-associated protein 22

5

0

High-throughput

0.694

High

1065610

BMS1
Ribosome biogenesis protein BMS1

4

2

High-throughput

0.694

High

678497

PWP2
Periodic tryptophan protein 2

4

3

High-throughput

0.691

High

383976

RS17A
Small ribosomal subunit protein eS17A

3

1

High-throughput

0.667

High

753677

RS3A1
Small ribosomal subunit protein eS1A

3

1

High-throughput

0.667

High

1039886

UTP17
NET1-associated nuclear protein 1

3

4

High-throughput

0.667

High

1056339

BFR2
Protein BFR2

3

1

High-throughput

0.667

High

763661

UTP20
U3 small nucleolar RNA-associated protein 20

4

0

High-throughput

0.664

High

919208

UTP8
U3 small nucleolar RNA-associated protein 8

4

0

Small-scale

0.664

High

1050225

RRP5
rRNA biogenesis protein RRP5

4

0

Small-scale

0.661

High

1053144

UTP13
U3 small nucleolar RNA-associated protein 13

3

4

High-throughput

0.656

High

1055457

RRP9
Ribosomal RNA-processing protein 9

3

2

High-throughput

0.656

High

1061656

RCL1
rRNA processing protein RCL1

3

1

High-throughput

0.656

High

1046837

UTP14
U3 small nucleolar RNA-associated protein 14

3

1

High-throughput

0.650

High

806607

UTP9
U3 small nucleolar RNA-associated protein 9

3

0

High-throughput

0.638

High

924674

NAT10
RNA cytidine acetyltransferase

3

0

High-throughput

0.638

High

1085063

RRP12
Ribosomal RNA-processing protein 12

3

0

High-throughput

0.638

High

511885

RS24A
Small ribosomal subunit protein eS24A

2

1

High-throughput

0.628

High

585422

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

1

High-throughput

0.628

High

689749

RS7A
Small ribosomal subunit protein eS7A

2

1

High-throughput

0.628

High

923278

ESF2
Pre-rRNA-processing protein ESF2

2

1

High-throughput

0.614

High

844686

UTP10
U3 small nucleolar RNA-associated protein 10

3

0

High-throughput

0.613

High

817666

UTP7
U3 small nucleolar RNA-associated protein 7

2

1

High-throughput

0.611

High

1084365

SAS10
Something about silencing protein 10

2

0

High-throughput

0.610

High

823420

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.588

High

1036441

UTP6
U3 small nucleolar RNA-associated protein 6

2

0

High-throughput

0.588

High

1403970

NOP14
Nucleolar complex protein 14

2

0

High-throughput

0.588

High

925228

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

2

1

High-throughput

0.586

High

826237

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

1064341

UTP16
U3 small nucleolar RNA-associated protein 16

2

0

High-throughput

0.585

High

512183

RS4A
Small ribosomal subunit protein eS4A

2

1

High-throughput

0.584

High

513929

RS11B
Small ribosomal subunit protein uS17B

2

1

High-throughput

0.584

High

1053547

UTP21
U3 small nucleolar RNA-associated protein 21

2

3

Small-scale

0.584

High

1056508

UTP4
U3 small nucleolar RNA-associated protein 4

2

4

Small-scale

0.584

High

1084434

RRP6
Exosome complex exonuclease RRP6

2

1

High-throughput

0.584

High

531948

RL4A
Large ribosomal subunit protein uL4A

2

0

High-throughput

0.576

High

580329

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.571

High

1043328

HAS1
ATP-dependent RNA helicase HAS1

2

1

High-throughput

0.571

High

672990

RRP43
Exosome complex component RRP43

2

0

High-throughput

0.559

High

826983

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

924009

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

528153

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

435474

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.547

High

779174

DHR2
Probable ATP-dependent RNA helicase DHR2

1

2

High-throughput

0.541

High

570327

RS17B
Small ribosomal subunit protein eS17B

1

1

High-throughput

0.536

High

1059265

TSR1
Ribosome biogenesis protein TSR1

1

2

High-throughput

0.536

High

546936

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

924142

SQS1
Protein SQS1

1

0

High-throughput

0.518

High

675307

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.513

High

722397

XPO1
Exportin-1

1

0

High-throughput

0.513

High

843296

KRI1
Protein KRI1

1

0

High-throughput

0.513

High

657017

BUR1
Serine/threonine-protein kinase BUR1

1

0

High-throughput

0.493

High

738351

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.493

High

817255

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.493

High

845915

NSE4
Non-structural maintenance of chromosome element 4

1

0

High-throughput

0.493

High

518171

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.480

High

393600

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

442202

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

455346

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

632774

DBP4
ATP-dependent RNA helicase HCA4

1

1

High-throughput

0.479

High

671294

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

678261

BUD23
18S rRNA

1

1

Small-scale

0.479

High

754365

DCA13
Protein SOF1

1

2

High-throughput

0.479

High

782127

RL1D1
Ribosome biogenesis protein UTP30

1

2

High-throughput

0.479

High

792339

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

793554

MAK5
ATP-dependent RNA helicase MAK5

1

3

High-throughput

0.479

High

802928

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.479

High

803978

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.479

High

804773

RRP4
Exosome complex component RRP4

1

1

High-throughput

0.479

High

808334

RRP8
25S rRNA

1

1

High-throughput

0.479

High

863159

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

864565

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.479

High

918917

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

924881

NOP15
Ribosome biogenesis protein 15

1

1

High-throughput

0.479

High

925180

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

963825

H3
Histone H3

1

3

High-throughput

0.479

High

1045140

UTP5
U3 small nucleolar RNA-associated protein 5

1

2

High-throughput

0.479

High

1046286

UTP15
U3 small nucleolar RNA-associated protein 15

1

2

High-throughput

0.479

High

1051184

FCF1
rRNA-processing protein FCF1

1

1

High-throughput

0.479

High

1051733

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

1053627

MRD1
Multiple RNA-binding domain-containing protein 1

1

1

Small-scale

0.479

High

1061965

RRP44
Exosome complex exonuclease DIS3

1

1

High-throughput

0.479

High

1065126

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.479

High

1084548

MAK21
Ribosome biogenesis protein MAK21

1

2

High-throughput

0.479

High

1084634

UTP12
U3 small nucleolar RNA-associated protein 12

1

3

High-throughput

0.479

High

1084711

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

1084949

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

1055175

CORO
Coronin-like protein

1

2

High-throughput

0.470

High

749742

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

796389

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

844502

GZF3
Protein GZF3

1

0

High-throughput

0.460

High

436565

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

513306

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

645021

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

673262

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

674923

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

694678

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

708674

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

710066

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

735250

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747069

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

0

High-throughput

0.458

High

758435

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

780875

MUD2
Splicing factor MUD2

1

0

Small-scale

0.458

High

786006

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

802472

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

804981

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

818367

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

825105

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

825581

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

826132

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

836222

DIM1
Dimethyladenosine transferase

1

0

Small-scale

0.458

High

852634

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

865440

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

871085

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

871145

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

874618

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

919064

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

1042295

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

1046342

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

1054919

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

1062925

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

1064321

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1084170

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

1084559

BBP
Branchpoint-bridging protein

1

0

Small-scale

0.458

High

1084867

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

1084983

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

1403971

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

525714

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

676514

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

924089

JJJ1
J protein JJJ1

1

1

High-throughput

0.445

High

503328

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

504501

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

1185449

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.437

High

752946

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

804601

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

746325

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.269

Low

919590

YG5B
Uncharacterized RNA-binding protein YGR250C

1

0

High-throughput

0.269

Low

548252

BIK1
Nuclear fusion protein BIK1

1

0

High-throughput

0.251

Low

672480

STE50
Protein STE50

1

0

High-throughput

0.251

Low

779818

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.251

Low

795299

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

812814

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

817488

VTC1
Vacuolar transporter chaperone complex subunit 1

1

0

High-throughput

0.249

Low

893410

MNN10
Probable alpha-1,6-mannosyltransferase MNN10

1

0

High-throughput

0.249

Low

918922

GYP2
GTPase-activating protein GYP2

1

0

High-throughput

0.249

Low

1043939

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

893269

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.232

Low

1038011

NU116
Nucleoporin NUP116/NSP116

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025