Interactor 1: CDC42 (P19073)
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)
Gene: CDC42

Interactor 2: GDIR (Q12434)
Rho GDP-dissociation inhibitor (Rho GDI)
Gene: RDI1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 10688190, 9242378, 17220465, 37968396, 21171963
Identification Methods two hybrid, coimmunoprecipitation, affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~Rho_GDI
Common GO terms GO:0005886 - plasma membrane
GO:0005934 - cellular bud tip
GO:0005935 - cellular bud neck
GO:0007015 - actin filament organization
GO:0007266 - Rho protein signal transduction
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Sc

1 202
+ Mm
+ Hs
+ At
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Ce
+ Ce
+ Ca
+ Cl

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024