HitPredict

Interactor 1: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: CP270 (P19225)
Cytochrome P450 2C70 (EC 1.14.14.-) (CYPIIC70) (Cytochrome P-450Md) (Cytochrome P450 P49)
Gene: Cyp2c70

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1383 Rn			1 489
+	Rn
		580500 INSR_RAT (1-1383): 0: 1592: 100.00		Q4QQW7_RAT (1-488): 0: 553: 59.51
+	Rn
		425991 INSR_RAT (1-1383): 0: 1592: 100.00		CP2C7_RAT (1-488): 0: 552: 59.51
+	Rn
		426006 INSR_RAT (1-1383): 0: 1592: 100.00		CP2E1_RAT (1-488): 0: 521: 51.33
+	Rn
		580435 INSR_RAT (1-1383): 0: 1592: 100.00		CP2CN_RAT (1-488): 1.68e-178: 511: 52.54
+	Rn
		425990 INSR_RAT (1-1383): 0: 1592: 100.00		CP2C6_RAT (13-489): 2.27e-175: 503: 60.25
+	Rn
		580542 INSR_RAT (1-1383): 0: 1592: 100.00		Q64648_RAT (18-489): 4.51e-175: 502: 56.45
+	Rn
		548309 INSR_RAT (1-1383): 0: 1592: 100.00		CP2A1_RAT (3-489): 2.78e-172: 495: 44.26
+	Rn
		560253 INSR_RAT (1-1383): 0: 1592: 100.00		CP2B3_RAT (41-487): 9.98e-161: 466: 43.30
+	Rn
		528929 INSR_RAT (1-1383): 0: 1592: 100.00		CP2DQ_RAT (41-487): 4.58e-152: 444: 36.73
+	Rn
		528928 INSR_RAT (1-1383): 0: 1592: 100.00		CP2D1_RAT (1-487): 2.39e-148: 435: 35.56
+	Rn
		416056 INSR_RAT (1-1383): 0: 1592: 100.00		CP1A2_RAT (5-470): 9.93e-60: 206: 30.25
+	At
		89471 PAM74_ARATH (504-1322): 0: 578: 12.43		C71BJ_ARATH (1-489): 8.09e-156: 454: 23.15
+	At
		89343 PAM74_ARATH (504-1322): 0: 578: 12.43		C83A1_ARATH (1-488): 4.92e-155: 452: 25.75
+	Hs
		710441 EPHA2_HUMAN (662-1354): 1.63e-170: 536: 23.02		CP2S1_HUMAN (50-488): 3.93e-148: 434: 42.31