Interactor 1: FAS2 (P19097)
Fatty acid synthase subunit alpha (EC 2.3.1.86) [Includes: Acyl carrier; 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (Beta-ketoacyl reductase); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) (Beta-ketoacyl synthase)]
Gene: FAS2

Interactor 2: FAS2 (P19097)
Fatty acid synthase subunit alpha (EC 2.3.1.86) [Includes: Acyl carrier; 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (Beta-ketoacyl reductase); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) (Beta-ketoacyl synthase)]
Gene: FAS2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 29557065, 18725634
Identification Methods affinity chromatography technology, x-ray crystallography
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ACPS~ACPS, Fas_alpha_ACP~ketoacyl-synt, FAS_I_H~FAS_I_H, FAS_I_H~ketoacyl-synt, FAS_I_H~Ketoacyl-synt_C, ketoacyl-synt~ketoacyl-synt, Ketoacyl-synt_C~ketoacyl-synt, Ketoacyl-synt_C~Ketoacyl-synt_C
Common GO terms GO:0000287 - magnesium ion binding
GO:0004312 - fatty acid synthase activity
GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004321 - fatty-acyl-CoA synthase activity
and 5 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1887
Sc

1 1887
+ Hs
+ Ss
+ Rn
+ Mt
+ Bs
+ Ec
+ Mt
+ Mt
+ Ec
+ Pa
+ Sc
+ Bs

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Last updated: 15 Jul 2024