HitPredict

Interactor 1: DDX17 (P19109)
ATP-dependent RNA helicase p62 (EC 3.6.4.13)
Gene: Rm62

Interactor 2: FMR1 (Q9NFU0)
Fragile X messenger ribonucleoprotein 1 homolog (FMRP) (dFMR1)
Gene: FMR1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	12368261, 30470739
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006417 - regulation of translation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 719 Dm			1 684
+	Hs
		571412 DDX5_HUMAN (194-719): 2.61e-160: 478: 56.82		FMR1_HUMAN (1-456): 0: 709: 40.27
+	Hs
		133996 DDX3X_HUMAN (129-694): 1.33e-148: 449: 36.78		FMR1_HUMAN (1-456): 0: 709: 40.27
+	Hs
		844176 DDX17_HUMAN (218-714): 1.94e-160: 482: 56.62		FXR2_HUMAN (4-484): 0: 664: 43.92
+	Hs
		133938 DDX3X_HUMAN (129-694): 1.33e-148: 449: 36.78		FXR1_HUMAN (1-412): 0: 691: 46.01
+	Mm
		729498 DDX3X_MOUSE (129-694): 1.98e-148: 449: 37.29		FMR1_MOUSE (1-456): 0: 672: 38.22
+	Hs
		133939 DDX3X_HUMAN (129-694): 1.33e-148: 449: 36.78		FXR2_HUMAN (4-484): 0: 664: 43.92
+	Mm
		1143617 DDX3X_MOUSE (129-694): 1.98e-148: 449: 37.29		Q8BPK8_MOUSE (1-342): 0: 614: 45.48