Protein: PXDN
Peroxidasin homolog (EC 1.11.2.-) (Melanoma-associated antigen MG50) (Peroxidasin 1) (hsPxd01) (Vascular peroxidase 1) (p53-responsive gene 2 protein) [Cleaved into: PXDN active fragment]

Gene: PXDN
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q92626

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001654 - eye development
GO:0004601 - peroxidase activity
GO:0005152 - interleukin-1 receptor antagonist activity
GO:0005201 - extracellular matrix structural constituent

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1144644

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

4

High-throughput

0.861

High

1366058

NELL1
Protein kinase C-binding protein NELL1

2

4

High-throughput

0.811

High

1366065

NELL2
Protein kinase C-binding protein NELL2

2

4

High-throughput

0.811

High

1047673

NOTC2
Neurogenic locus notch homolog protein 2

2

2

High-throughput

0.776

High

133040

MATN2
Matrilin-2

1

1

High-throughput

0.691

High

567933

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.691

High

593459

PGFRA
Platelet-derived growth factor receptor alpha

1

8

High-throughput

0.691

High

1366081

CLC4A
C-type lectin domain family 4 member A

1

11

High-throughput

0.691

High

1366083

INSL5
Insulin-like peptide INSL5

1

1

High-throughput

0.691

High

1065011

FGL1
Fibrinogen-like protein 1

4

3

High-throughput

0.691

High

377315

VIP
VIP peptides [Cleaved into: Intestinal peptide PHV-42

3

1

High-throughput

0.662

High

1366076

FBX6
F-box only protein 6

5

10

High-throughput

0.650

High

955439

CDC42
Cell division control protein 42 homolog

1

8

High-throughput

0.647

High

1042655

UPAR
Urokinase plasminogen activator surface receptor

3

0

High-throughput

0.638

High

1366070

CNPY3
Protein canopy homolog 3

4

3

High-throughput

0.630

High

948008

DEF1
Neutrophil defensin 1

2

1

High-throughput

0.628

High

1052373

RN5A
2-5A-dependent ribonuclease

1

3

High-throughput

0.618

High

412363

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.618

High

615191

PACA
Pituitary adenylate cyclase-activating polypeptide

2

1

High-throughput

0.611

High

1366069

ERP44
Endoplasmic reticulum resident protein 44

2

0

High-throughput

0.602

High

1359216

CA054
Uncharacterized protein C1orf54

2

2

High-throughput

0.601

High

1360138

PATE1
Prostate and testis expressed protein 1

2

1

High-throughput

0.601

High

1366080

FBX2
F-box only protein 2

2

10

High-throughput

0.601

High

253450

CST8
Cystatin-8

2

0

High-throughput

0.576

High

976842

LCN6
Epididymal-specific lipocalin-6

2

0

High-throughput

0.576

High

157693

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.553

High

1250180

LRC31
Leucine-rich repeat-containing protein 31

1

2

High-throughput

0.553

High

1254882

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.553

High

564147

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

682563

S100P
Protein S100-P

1

2

High-throughput

0.536

High

686847

S10A4
Protein S100-A4

1

2

High-throughput

0.536

High

698964

CALX
Calnexin

1

9

High-throughput

0.536

High

1030199

IL5RA
Interleukin-5 receptor subunit alpha

1

2

High-throughput

0.536

High

1101394

SG2A2
Mammaglobin-A

1

1

High-throughput

0.536

High

1366057

GGH
Gamma-glutamyl hydrolase

1

1

High-throughput

0.536

High

1366071

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

2

High-throughput

0.536

High

1366074

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.536

High

396631

ESR1
Estrogen receptor

2

6

High-throughput

0.521

High

841571

I12R1
Interleukin-12 receptor subunit beta-1

1

6

High-throughput

0.514

High

316682

LY6H
Lymphocyte antigen 6H

1

0

High-throughput

0.513

High

518885

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.513

High

933204

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

1249676

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.513

High

1366064

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.513

High

1366067

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.513

High

1366072

PG12A
Group XIIA secretory phospholipase A2

1

0

High-throughput

0.493

High

706244

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

1256438

CRACD
Capping protein-inhibiting regulator of actin dynamics

1

4

High-throughput

0.489

High

1366062

F120B
Constitutive coactivator of peroxisome proliferator-activated receptor gamma

1

1

High-throughput

0.489

High

1366066

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

1

High-throughput

0.489

High

1366079

HSFX1
Heat shock transcription factor, X-linked

1

1

High-throughput

0.489

High

192507

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.479

High

914313

EFNA4
Ephrin-A4

1

1

High-throughput

0.479

High

951315

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

1113883

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1231129

SCAR3
Scavenger receptor class A member 3

1

2

High-throughput

0.479

High

1366084

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.479

High

820795

TACT
T-cell surface protein tactile

1

0

High-throughput

0.458

High

143749

WN10B
Protein Wnt-10b

1

1

High-throughput

0.445

High

170903

CLGN
Calmegin

1

9

High-throughput

0.445

High

1063824

LG3BP
Galectin-3-binding protein

1

3

High-throughput

0.445

High

1245898

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.445

High

1324261

LYPD1
Ly6/PLAUR domain-containing protein 1

1

1

High-throughput

0.445

High

1366063

HIPL1
HHIP-like protein 1

1

1

High-throughput

0.445

High

212294

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

2

High-throughput

0.437

High

218567

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

1137905

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.437

High

1249070

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1366056

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

1366073

RN208
RING finger protein 208

1

2

Small-scale

0.437

High

1366077

T106B
Transmembrane protein 106B

1

2

High-throughput

0.437

High

1366078

HECW2
E3 ubiquitin-protein ligase HECW2

1

1

High-throughput

0.437

High

251941

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

0

High-throughput

0.426

High

1366082

KLDC2
Kelch domain-containing protein 2

1

2

High-throughput

0.407

High

1366060

HAUS1
HAUS augmin-like complex subunit 1

2

0

High-throughput

0.328

High

1246137

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

0

High-throughput

0.279

Low

1366068

CENPK
Centromere protein K

1

0

High-throughput

0.279

Low

853119

ACDSB
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.269

Low

1278237

BNIPL
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein

1

0

High-throughput

0.251

Low

1366059

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.249

Low

1366061

FXRD1
FAD-dependent oxidoreductase domain-containing protein 1

1

0

High-throughput

0.249

Low

1366075

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.249

Low

765756

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.232

Low

1328022

RP25L
Ribonuclease P protein subunit p25-like protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025