HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: COF1 (P45592)
Cofilin-1 (Cofilin, non-muscle isoform)
Gene: Cfl1

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030426 - growth cone GO:0043025 - neuronal cell body
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 166
+	Rn
		94167 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		COF1_RAT (1-166): 2.94e-74: 221: 100.00
+	Mm
		497923 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		COF1_MOUSE (1-166): 1.39e-74: 222: 99.40
+	Mm
		498155 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		DEST_MOUSE (1-166): 4.56e-71: 213: 70.48
+	Hs
		496321 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		COF1_HUMAN (1-166): 2.75e-74: 221: 99.40
+	Hs
		497833 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		COF2_HUMAN (1-166): 1.05e-72: 217: 81.33
+	Hs
		496692 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		DEST_HUMAN (1-166): 7.52e-70: 210: 71.08
+	Hs
		496930 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TWF1_HUMAN (3-144): 1.11e-33: 123: 22.07
+	Dm
		799778 Q9VLS7_DROME (3-541): 3.66e-12: 72.4: 11.77		CADF_DROME (1-153): 3.35e-37: 126: 33.33