Protein: CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Voltage-gated calcium channel subunit alpha Cav2.1)

Gene: CAC1A, CACNA1A
Organism: Homo sapiens
Interactions: 103
UniProt ID: O00555

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0005245 - voltage-gated calcium channel activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

139752

CABP1
Calcium-binding protein 1

2

4

Small-scale

0.757

High

132949

MATN2
Matrilin-2

1

11

High-throughput

0.637

High

131544

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

2

20

Small-scale

0.602

High

139676

VWF
von Willebrand factor

1

2

High-throughput

0.587

High

139671

AGRL1
Adhesion G protein-coupled receptor L1

1

8

High-throughput

0.573

High

139672

RIMB1
Peripheral-type benzodiazepine receptor-associated protein 1

1

11

High-throughput

0.573

High

139677

LAMB1
Laminin subunit beta-1

1

4

High-throughput

0.573

High

139694

YLPM1
YLP motif-containing protein 1

1

4

High-throughput

0.573

High

139720

AMGO2
Amphoterin-induced protein 2

1

1

High-throughput

0.573

High

139743

TBB2B
Tubulin beta-2B chain

1

8

High-throughput

0.573

High

136740

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

9

High-throughput

0.552

High

139680

ZEP1
Zinc finger protein 40

1

2

High-throughput

0.552

High

139683

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.552

High

139719

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

11

High-throughput

0.552

High

139697

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.549

High

139718

RHG22
Rho GTPase-activating protein 22

1

0

High-throughput

0.549

High

139724

ABI1
Abl interactor 1

1

0

High-throughput

0.549

High

139688

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.536

High

139670

DNJB5
DnaJ homolog subfamily B member 5

1

0

High-throughput

0.529

High

139686

GRN
Progranulin

1

0

High-throughput

0.529

High

139723

RB12B
RNA-binding protein 12B

1

10

High-throughput

0.523

High

139755

PUF60
Poly(U)-binding-splicing factor PUF60

1

13

High-throughput

0.523

High

139711

FSCN1
Fascin

1

0

High-throughput

0.513

High

139664

RIMB2
RIMS-binding protein 2

1

9

High-throughput

0.508

High

139665

SPY1
Protein sprouty homolog 1

1

1

High-throughput

0.508

High

139667

KALRN
Kalirin

1

2

High-throughput

0.508

High

139669

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

2

High-throughput

0.508

High

139679

ACTN1
Alpha-actinin-1

1

3

High-throughput

0.508

High

139682

SCP2
Sterol carrier protein 2

1

2

High-throughput

0.508

High

139687

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

4

High-throughput

0.508

High

139690

TSN7
Tetraspanin-7

1

3

High-throughput

0.508

High

139691

MATK
Megakaryocyte-associated tyrosine-protein kinase

1

5

High-throughput

0.508

High

139692

NOTC1
Neurogenic locus notch homolog protein 1

1

8

High-throughput

0.508

High

139699

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

3

High-throughput

0.508

High

139700

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

4

High-throughput

0.508

High

139701

SRSF1
Serine/arginine-rich splicing factor 1

1

9

High-throughput

0.508

High

139703

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

4

High-throughput

0.508

High

139705

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

12

High-throughput

0.508

High

139710

T22D1
TSC22 domain family protein 1

1

1

High-throughput

0.508

High

139712

TGO1
Transport and Golgi organization protein 1 homolog

1

10

High-throughput

0.508

High

139717

HECW1
E3 ubiquitin-protein ligase HECW1

1

20

High-throughput

0.508

High

139731

RBP56
TATA-binding protein-associated factor 2N

1

2

High-throughput

0.508

High

139733

NELL1
Protein kinase C-binding protein NELL1

1

12

High-throughput

0.508

High

139737

AP2M1
AP-2 complex subunit mu

1

2

High-throughput

0.508

High

139741

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

9

High-throughput

0.508

High

139742

NELL2
Protein kinase C-binding protein NELL2

1

16

High-throughput

0.508

High

139745

ABCA2
ATP-binding cassette sub-family A member 2

1

1

High-throughput

0.508

High

139746

PP12C
Protein phosphatase 1 regulatory subunit 12C

1

8

High-throughput

0.508

High

139753

CRIM1
Cysteine-rich motor neuron 1 protein

1

12

High-throughput

0.508

High

139756

JAG2
Protein jagged-2

1

4

High-throughput

0.508

High

139668

MEGF6
Multiple epidermal growth factor-like domains protein 6

1

7

High-throughput

0.504

High

139726

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

10

High-throughput

0.504

High

139681

SYT1
Synaptotagmin-1

1

12

Small-scale

0.501

High

66410

ZN233
Zinc finger protein 233

1

0

High-throughput

0.486

High

67816

SRRM4
Serine/arginine repetitive matrix protein 4

1

0

High-throughput

0.486

High

139666

GET3
ATPase GET3

1

0

High-throughput

0.486

High

139675

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.486

High

139678

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.486

High

139696

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.486

High

139704

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.486

High

139709

L2GL1
Lethal(2) giant larvae protein homolog 1

1

0

High-throughput

0.486

High

139722

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.486

High

139725

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

0

High-throughput

0.486

High

139727

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

1

0

High-throughput

0.486

High

139728

OLIG1
Oligodendrocyte transcription factor 1

1

0

High-throughput

0.486

High

139730

IP6K1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.486

High

139734

PMM1
Phosphomannomutase 1

1

0

High-throughput

0.486

High

139735

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.486

High

139736

MOAP1
Modulator of apoptosis 1

1

0

High-throughput

0.486

High

139744

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

0

High-throughput

0.486

High

139749

MANBL
Protein MANBAL

1

0

High-throughput

0.486

High

139757

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.486

High

139707

BTG3
Protein BTG3

1

1

High-throughput

0.481

High

139693

MAP1B
Microtubule-associated protein 1B

1

6

Small-scale

0.479

High

139695

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

8

Small-scale

0.479

High

139698

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

3

Small-scale

0.479

High

139716

TECT3
Tectonic-3

1

1

High-throughput

0.479

High

139739

TECT2
Tectonic-2

1

1

High-throughput

0.479

High

70031

CRTP1
Cysteine-rich tail protein 1

1

1

High-throughput

0.464

High

139674

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

12

High-throughput

0.464

High

139684

FBLN1
Fibulin-1

1

14

High-throughput

0.464

High

139685

SYVC
Valine--tRNA ligase

1

2

High-throughput

0.464

High

139702

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

13

High-throughput

0.464

High

139732

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

4

High-throughput

0.464

High

139750

KLHL1
Kelch-like protein 1

1

0

Small-scale

0.458

High

139754

KDM5B
Lysine-specific demethylase 5B

1

0

Small-scale

0.458

High

139740

Q96I11
CRMP1 protein

1

3

High-throughput

0.457

High

139706

DPYL1
Dihydropyrimidinase-related protein 1

1

3

High-throughput

0.439

High

139708

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

12

High-throughput

0.439

High

139751

LTBP3
Latent-transforming growth factor beta-binding protein 3

1

14

High-throughput

0.439

High

64981

GG6L9
Golgin subfamily A member 6-like protein 9

1

12

High-throughput

0.417

High

85479

B7ZLY3
LTBP1 protein

1

13

High-throughput

0.417

High

86286

B9EG76
Latent-transforming growth factor beta-binding protein 3

1

13

High-throughput

0.417

High

139713

Q5XG79
AGRN protein

1

10

High-throughput

0.417

High

139715

Q6IAU3
BTG family, member 3, isoform CRA_b

1

1

High-throughput

0.417

High

139729

Q8TAS6
LAMB1 protein

1

7

High-throughput

0.417

High

139673

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

0

High-throughput

0.265

Low

139689

PTGDS
Prostaglandin-H2 D-isomerase

1

0

High-throughput

0.265

Low

139721

NOXA1
NADPH oxidase activator 1

1

0

High-throughput

0.265

Low

139738

WBP1
WW domain-binding protein 1

1

0

High-throughput

0.265

Low

139747

HHATL
Protein-cysteine N-palmitoyltransferase HHAT-like protein

1

0

High-throughput

0.265

Low

139748

ZCC17
Zinc finger CCHC domain-containing protein 17

1

0

High-throughput

0.265

Low

139714

TRIQK
Triple QxxK/R motif-containing protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025