HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: GFAP (P47819)
Glial fibrillary acidic protein (GFAP)
Gene: GFAP

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0031175 - neuron projection development GO:0044297 - cell body GO:0097386 - glial cell projection
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 752 Rn			1 430
+	Rn
		94169 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		GFAP_RAT (1-430): 9.55e-146: 423: 100.00
+	Mm
		372929 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		GFAP_MOUSE (1-430): 2.47e-143: 417: 96.28
+	Hs
		496206 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		GFAP_HUMAN (1-430): 6.52e-143: 416: 91.67
+	Hs
		443287 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		VIME_HUMAN (4-429): 3.29e-140: 410: 57.48
+	Hs
		496488 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		PERI_HUMAN (47-427): 7.7e-108: 328: 56.66
+	Rn
		581925 TAU_RAT (1-752): 2.4e-95: 314: 100.00		AINX_RAT (35-385): 7.7e-79: 254: 49.72
+	Rn
		94148 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		AINX_RAT (35-385): 7.7e-79: 254: 49.72
+	Rn
		581922 TAU_RAT (1-752): 2.4e-95: 314: 100.00		NFL_RAT (43-376): 9.45e-74: 242: 48.37
+	Rn
		94145 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		NFL_RAT (43-376): 9.45e-74: 242: 48.37
+	Rn
		522304 TAU_RAT (1-752): 2.4e-95: 314: 100.00		NFM_RAT (54-376): 1.53e-70: 239: 46.32
+	Rn
		94135 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		NFM_RAT (54-376): 1.53e-70: 239: 46.32
+	Hs
		497096 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AINX_HUMAN (35-385): 6.99e-83: 265: 49.44
+	Mm
		440283 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		NFM_MOUSE (54-376): 7.62e-70: 238: 46.32
+	Hs
		496199 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		K2C5_HUMAN (33-378): 1.77e-75: 248: 33.05
+	Hs
		422133 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		NFL_HUMAN (43-376): 1.55e-75: 246: 48.21
+	Hs
		422332 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		NFM_HUMAN (60-376): 3.79e-72: 245: 47.50
+	Hs
		359457 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		K2C6A_HUMAN (33-394): 3.66e-74: 243: 31.06
+	Hs
		422135 MTAP2_HUMAN (42-752): 4.53e-33: 139: 24.66		NFL_HUMAN (43-376): 1.55e-75: 246: 48.21
+	Hs
		422166 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		NFL_HUMAN (43-376): 1.55e-75: 246: 48.21
+	Hs
		422380 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		NFM_HUMAN (60-376): 3.79e-72: 245: 47.50