HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: DPYL2 (P47942)
Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (Turned on after division 64 kDa protein) (TOAD-64)
Gene: Dpysl2

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0030424 - axon GO:0030425 - dendrite GO:0030426 - growth cone and 1 others more... GO:0043025 - neuronal cell body
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 572
+	Rn
		94172 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		DPYL2_RAT (1-572): 0: 779: 100.00
+	Rn
		582008 TAU_RAT (1-752): 2.4e-95: 314: 100.00		DPYL1_RAT (1-572): 0: 760: 75.87
+	Rn
		94232 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		DPYL1_RAT (1-572): 0: 760: 75.87
+	Hs
		497102 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		DPYL2_HUMAN (1-572): 0: 780: 98.78
+	Mm
		498057 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		DPYL3_MOUSE (1-571): 0: 753: 76.36
+	Hs
		497005 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		DPYL1_HUMAN (1-572): 0: 770: 76.40
+	Hs
		497006 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		DPYL3_HUMAN (1-571): 0: 755: 77.41
+	Hs
		147310 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		DPYL4_HUMAN (1-571): 0: 750: 76.01
+	Hs
		497508 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		DPYL5_HUMAN (13-567): 0: 662: 52.24