Protein: ML12A
Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)

Gene: ML12A, MYL12A
Organism: Homo sapiens
Interactions: 142
UniProt ID: P19105

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016459 - myosin complex
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580614

MYH9
Myosin-9

2

19

High-throughput

0.811

High

580672

MY18A
Unconventional myosin-XVIIIa

2

20

High-throughput

0.811

High

580648

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

2

11

High-throughput

0.754

High

159539

ML12B
Myosin regulatory light chain 12B

2

17

High-throughput

0.737

High

580607

MYL9
Myosin regulatory light polypeptide 9

1

16

High-throughput

0.691

High

580615

MYH10
Myosin-10

1

19

High-throughput

0.691

High

580629

NEK4
Serine/threonine-protein kinase Nek4

1

20

High-throughput

0.691

High

580665

MYH14
Myosin-14

1

19

High-throughput

0.691

High

580677

MYO19
Unconventional myosin-XIX

1

20

High-throughput

0.691

High

580625

GSK3A
Glycogen synthase kinase-3 alpha

1

19

High-throughput

0.656

High

528514

CFTR
Cystic fibrosis transmembrane conductance regulator

3

4

High-throughput

0.650

High

148383

CTRO
Citron Rho-interacting kinase

1

20

Small-scale

0.647

High

580651

MYLK
Myosin light chain kinase, smooth muscle

1

18

Small-scale

0.647

High

580656

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

15

Small-scale

0.647

High

167466

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

17

High-throughput

0.618

High

580616

MYH11
Myosin-11

1

19

High-throughput

0.618

High

580617

TAGL2
Transgelin-2

1

19

High-throughput

0.618

High

580627

CDK7
Cyclin-dependent kinase 7

1

7

High-throughput

0.618

High

580647

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.618

High

580685

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

9

High-throughput

0.618

High

580702

TNIK
TRAF2 and NCK-interacting protein kinase

1

6

High-throughput

0.618

High

580706

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

14

High-throughput

0.618

High

580635

GRB2
Growth factor receptor-bound protein 2

2

1

High-throughput

0.601

High

373655

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.586

High

580654

LARP7
La-related protein 7

2

3

High-throughput

0.584

High

226482

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.571

High

368959

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

580628

CDK9
Cyclin-dependent kinase 9

1

9

High-throughput

0.553

High

388218

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.541

High

128433

DNM1L
Dynamin-1-like protein

1

1

High-throughput

0.536

High

409446

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

19

High-throughput

0.536

High

538637

MYL6B
Myosin light chain 6B

1

19

High-throughput

0.536

High

580604

VDAC1
Voltage-dependent anion-selective channel protein 1

1

2

High-throughput

0.536

High

580623

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.536

High

580632

MYL6
Myosin light polypeptide 6

1

18

High-throughput

0.536

High

580643

FLII
Protein flightless-1 homolog

1

3

High-throughput

0.536

High

580653

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

2

High-throughput

0.536

High

580683

KIF2C
Kinesin-like protein KIF2C

1

10

High-throughput

0.536

High

580696

ANLN
Anillin

1

4

High-throughput

0.536

High

580697

PDLI7
PDZ and LIM domain protein 7

1

4

High-throughput

0.536

High

580620

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

3

Small-scale

0.516

High

239767

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.514

High

580669

IPO4
Importin-4

1

0

High-throughput

0.513

High

580682

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.513

High

580684

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

580631

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.501

High

580619

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

580673

ESR2
Estrogen receptor beta

1

4

Small-scale

0.489

High

580680

RSF1
Remodeling and spacing factor 1

1

12

High-throughput

0.489

High

580707

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

19

High-throughput

0.489

High

266908

SRS10
Serine/arginine-rich splicing factor 10

1

1

Small-scale

0.479

High

301607

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

High-throughput

0.479

High

302884

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

313748

SVIL
Supervillin

1

2

Small-scale

0.479

High

345320

FOS
Protein c-Fos

1

2

High-throughput

0.479

High

345889

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

397769

ISG15
Ubiquitin-like protein ISG15

1

5

High-throughput

0.479

High

434933

SP1
Transcription factor Sp1

1

4

Small-scale

0.479

High

450710

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.479

High

453136

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.479

High

501658

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

530415

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

580605

CBL
E3 ubiquitin-protein ligase CBL

1

9

High-throughput

0.479

High

580606

CRCM
Colorectal mutant cancer protein

1

18

High-throughput

0.479

High

580608

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

High-throughput

0.479

High

580609

S10A4
Protein S100-A4

1

1

High-throughput

0.479

High

580610

PML
Protein PML

1

11

High-throughput

0.479

High

580618

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.479

High

580622

YAP1
Transcriptional coactivator YAP1

1

4

High-throughput

0.479

High

580624

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

580630

MOT1
Monocarboxylate transporter 1

1

1

High-throughput

0.479

High

580637

ACTC
Actin, alpha cardiac muscle 1

1

5

High-throughput

0.479

High

580640

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.479

High

580641

TP53B
TP53-binding protein 1

1

3

High-throughput

0.479

High

580642

TRI26
Tripartite motif-containing protein 26

1

1

Small-scale

0.479

High

580645

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

580646

CUL3
Cullin-3

1

1

High-throughput

0.479

High

580650

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

580657

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

580660

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

580661

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

6

High-throughput

0.479

High

580662

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

580667

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

580671

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

580674

REQU
Zinc finger protein ubi-d4

1

5

High-throughput

0.479

High

580675

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

580681

RUFY1
RUN and FYVE domain-containing protein 1

1

16

High-throughput

0.479

High

580686

MEP50
Methylosome protein WDR77

1

4

High-throughput

0.479

High

580688

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.479

High

580689

TRI31
E3 ubiquitin-protein ligase TRIM31

1

1

High-throughput

0.479

High

580693

ECT2
Protein ECT2

1

7

High-throughput

0.479

High

580694

SENP2
Sentrin-specific protease 2

1

1

Small-scale

0.479

High

580698

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

580703

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

2

High-throughput

0.479

High

580705

TRAF6
TNF receptor-associated factor 6

1

5

High-throughput

0.479

High

580708

NEMO
NF-kappa-B essential modulator

1

20

High-throughput

0.479

High

580692

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

2

High-throughput

0.464

High

233207

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

277928

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.458

High

294348

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

382301

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.458

High

569159

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

580612

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

580634

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

580658

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

580668

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

580670

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

580695

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

580700

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

580701

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

580704

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

580687

KLF16
Krueppel-like factor 16

1

2

High-throughput

0.457

High

496267

TAU
Microtubule-associated protein tau

1

10

High-throughput

0.445

High

580613

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

580636

1433Z
14-3-3 protein zeta/delta

1

9

High-throughput

0.445

High

580638

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

3

High-throughput

0.445

High

580666

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

8

High-throughput

0.445

High

580678

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

14

High-throughput

0.445

High

580691

P63
Tumor protein 63

1

5

Small-scale

0.445

High

352482

TNFA
Tumor necrosis factor

1

1

High-throughput

0.437

High

441873

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.437

High

580603

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

2

High-throughput

0.437

High

580626

DNLI4
DNA ligase 4

1

1

High-throughput

0.437

High

580633

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

580639

GOGA2
Golgin subfamily A member 2

1

17

High-throughput

0.437

High

580644

TIF1B
Transcription intermediary factor 1-beta

1

10

High-throughput

0.437

High

580649

MDC1
Mediator of DNA damage checkpoint protein 1

1

4

High-throughput

0.437

High

580652

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

580659

TET2
Methylcytosine dioxygenase TET2

1

1

Small-scale

0.437

High

580663

PAXI1
PAX-interacting protein 1

1

6

High-throughput

0.437

High

580664

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.437

High

580699

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

401394

JUN
Transcription factor Jun

1

1

High-throughput

0.407

High

580676

LIN37
Protein lin-37 homolog

1

1

Small-scale

0.407

High

580611

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

239491

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.269

Low

353257

CD4
T-cell surface glycoprotein CD4

1

0

Small-scale

0.249

Low

580621

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.249

Low

580679

KCD15
BTB/POZ domain-containing protein KCTD15

1

0

Small-scale

0.249

Low

580690

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

320974

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.232

Low

580655

LIN9
Protein lin-9 homolog

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024