Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: MP2K1 (Q01986)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: Map2k1

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 32357304
Identification Methods cross-linking study
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0010629 - negative regulation of gene expression
GO:0014069 - postsynaptic density
GO:0019901 - protein kinase binding
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 752
Rn

1 393
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024